{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:08:25Z","timestamp":1790752105059,"version":"4.1.0"},"reference-count":45,"publisher":"Frontiers Media SA","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Neurosci."],"DOI":"10.3389\/fnins.2015.00190","type":"journal-article","created":{"date-parts":[[2015,5,27]],"date-time":"2015-05-27T09:48:50Z","timestamp":1432720130000},"source":"Crossref","is-referenced-by-count":39,"title":["Pineal melatonin is a circadian time-giver for leptin rhythm in Syrian hamsters"],"prefix":"10.3389","volume":"9","author":[{"given":"Ibtissam","family":"Chakir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00c3\u00a9phanie","family":"Dumont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"P\u00c3\u00a9vet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Ouarour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Challet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Vuillez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2015,5,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.neuroscience.2006.09.030","article-title":"Melatonin affects nuclear orphan receptors mRNA in the rat suprachiasmatic nuclei","volume":"144","author":"Agez","year":"2007","journal-title":"Neuroscience"},{"key":"B2","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1146\/annurev.physiol.62.1.413","article-title":"Leptin","volume":"62","author":"Ahima","year":"2000","journal-title":"Annu. Rev. Physiol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1046\/j.1365-201x.2000.00746.x","article-title":"Diurnal variation in circulating leptin is dependent on gender, food intake and circulating insulin in mice","volume":"169","author":"Ahren","year":"2000","journal-title":"Acta Physiol. Scand"},{"key":"B4","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1111\/j.1600-079X.2008.00610.x","article-title":"Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes","volume":"45","author":"Alonso-Vale","year":"2008","journal-title":"J. Pineal Res"},{"key":"B5","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1055\/s-2004-825723","article-title":"Light\/dark cycle-dependent metabolic changes in adipose tissue of pinealectomized rats","volume":"36","author":"Alonso-Vale","year":"2004","journal-title":"Horm. Metab. Res"},{"key":"B6","doi-asserted-by":"publisher","first-page":"2344","DOI":"10.1126\/science.289.5488.2344","article-title":"Resetting of circadian time in peripheral tissues by glucocorticoid signaling","volume":"289","author":"Balsalobre","year":"2000","journal-title":"Science"},{"key":"B7","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/0149-7634(85)90006-5","article-title":"Photoperiodic control of seasonal body weight cycles in hamsters","volume":"9","author":"Bartness","year":"1985","journal-title":"Neurosci. Biobehav. Rev"},{"key":"B8","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.yhbeh.2008.10.015","article-title":"From daily behavior to hormonal and neurotransmitters rhythms: comparison between diurnal and nocturnal rat species","volume":"55","author":"Cuesta","year":"2009","journal-title":"Horm. Behav"},{"key":"B9","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1111\/j.1365-2826.2007.01564.x","article-title":"Does a melatonin-dependent circadian oscillator in the pars tuberalis drive prolactin seasonal rhythmicity?","volume":"19","author":"Dardente","year":"2007","journal-title":"J. Neuroendocrinol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3109\/07420528709078520","article-title":"Circadian and seasonal variations of plasma insulin and cortisol concentrations in the Syrian hamster, Mesocricetus auratus","volume":"4","author":"de Souza","year":"1987","journal-title":"Chronobiol. Int"},{"key":"B11","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1677\/JOE-08-0415","article-title":"Glucocorticoids and the circadian clock","volume":"200","author":"Dickmeis","year":"2009","journal-title":"J. Endocrinol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.pneurobio.2010.12.004","article-title":"Melatonin\u00e2\u20ac\u201ca pleiotropic, orchestrating regulator molecule","volume":"93","author":"Hardeland","year":"2011","journal-title":"Prog Neurobiol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1006\/hbeh.2000.1592","article-title":"Twenty-four-hour profiles of serum leptin in siberian and golden hamsters: photoperiodic and diurnal variations","volume":"37","author":"Horton","year":"2000","journal-title":"Horm. Behav"},{"key":"B14","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1002\/dneu.22213","article-title":"Melatonin administered during the fetal stage affects circadian clock in the suprachiasmatic nucleus but not in the liver","volume":"75","author":"Houdek","year":"2015","journal-title":"Dev. Neurobiol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1210\/endo.142.6.8197","article-title":"The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels","volume":"142","author":"Kalsbeek","year":"2001","journal-title":"Endocrinology"},{"key":"B16","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/BF01262958","article-title":"Effect of neonatal pinealectomy on circadian periodicity of adrenocortical activity","volume":"66","author":"Kaplanski","year":"1986","journal-title":"J. Neural Transm"},{"key":"B17","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1080\/07420520500545821","article-title":"Suprachiasmatic nuclei may regulate the rhythm of leptin hormone release in Syrian hamsters (Mesocricetus auratus)","volume":"23","author":"Karakas","year":"2006","journal-title":"Chronobiol. Int"},{"key":"B18","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1159\/000048238","article-title":"Circadian rhythms of dopamine and dihydroxyphenyl acetic acid in the mouse striatum: effects of pinealectomy and of melatonin treatment","volume":"75","author":"Khaldy","year":"2002","journal-title":"Neuroendocrinology"},{"key":"B19","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1046\/j.1365-2826.1999.00373.x","article-title":"A suprachiasmatic nucleus generated rhythm in basal glucose concentrations","volume":"11","author":"La Fleur","year":"1999","journal-title":"J. Neuroendocrinol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1046\/j.1365-2826.2001.00717.x","article-title":"Role for the pineal and melatonin in glucose homeostasis: pinealectomy increases night-time glucose concentrations","volume":"13","author":"la Fleur","year":"2001","journal-title":"J. Neuroendocrinol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"5165","DOI":"10.1210\/en.2007-0526","article-title":"Daily rhythm of tryptophan hydroxylase-2 messenger ribonucleic acid within raphe neurons is induced by corticoid daily surge and modulated by enhanced locomotor activity","volume":"148","author":"Malek","year":"2007","journal-title":"Endocrinology"},{"key":"B22","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1177\/074873001129002051","article-title":"Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin","volume":"16","author":"Malpaux","year":"2001","journal-title":"J. Biol. Rhythms"},{"key":"B23","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1097\/00001756-200103050-00029","article-title":"Tissue-specific abolition of Per1 expression in the pars tuberalis by pinealectomy in the Syrian hamster","volume":"12","author":"Messager","year":"2001","journal-title":"Neuroreport"},{"key":"B24","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.ygcen.2012.06.023","article-title":"Plasticity in photoperiodic regulation of adrenal, but not testicular, function in Syrian hamsters","volume":"178","author":"Morgan","year":"2012","journal-title":"Gen. Comp. Endocrinol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1111\/j.1460-9568.2010.07586.x","article-title":"Glucocorticoid-mediated nycthemeral and photoperiodic regulation of tph2 expression","volume":"33","author":"Nexon","year":"2011","journal-title":"Eur. J. Neurosci"},{"key":"B26","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1093\/dnares\/dsi003","article-title":"Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver","volume":"12","author":"Oishi","year":"2005","journal-title":"DNA Res"},{"key":"B27","first-page":"R321","article-title":"Adrenal, thyroid, and testicular hormone rhythms in male golden hamsters on long and short days","volume":"253","author":"Ottenweller","year":"1987","journal-title":"Am. J. Physiol"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.3109\/07420520903412368","article-title":"Circadian rhythmicity in murine pre-adipocyte and adipocyte cells","volume":"26","author":"Otway","year":"2009","journal-title":"Chronobiol. Int"},{"key":"B29","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1111\/j.1600-079X.1984.tb00209.x","article-title":"Effects of pinealectomy and aging on the serum corticosterone circadian rhythm in rats","volume":"1","author":"Oxenkrug","year":"1984","journal-title":"J. Pineal Res"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1007\/s001250051034","article-title":"Evidence for a circadian rhythm of insulin release from perifused rat pancreatic islets","volume":"41","author":"Peschke","year":"1998","journal-title":"Diabetologia"},{"key":"B31","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1046\/j.1365-2826.2003.01017.x","article-title":"Melatonin: from seasonal to circadian signal","volume":"15","author":"Pevet","year":"2003","journal-title":"J. Neuroendocrinol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.jphysparis.2011.07.001","article-title":"Melatonin: both master clock output and internal time-giver in the circadian clocks network","volume":"105","author":"Pevet","year":"2011","journal-title":"J. Physiol. Paris"},{"key":"B33","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.bbi.2013.02.007","article-title":"Impaired leukocyte trafficking and skin inflammatory responses in hamsters lacking a functional circadian system","volume":"32","author":"Prendergast","year":"2013","journal-title":"Brain Behav. Immun"},{"key":"B34","doi-asserted-by":"publisher","first-page":"5347","DOI":"10.1210\/en.2003-0693","article-title":"Melatonin reduces body weight gain in sprague dawley rats with diet-induced obesity","volume":"144","author":"Prunet-Marcassus","year":"2003","journal-title":"Endocrinology"},{"key":"B35","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0031-9384(84)90106-9","article-title":"Metabolic fuel homeostasis in Syrian hamsters: nycthemeral and exercise variables","volume":"33","author":"Rowland","year":"1984","journal-title":"Physiol. Behav"},{"key":"B36","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/0006-8993(93)90683-E","article-title":"Regulation of melatonin-sensitivity and firing-rate rhythms of hamster suprachiasmatic nucleus neurons: pinealectomy effects","volume":"602","author":"Rusak","year":"1993","journal-title":"Brain Res"},{"key":"B37","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1159\/000054670","article-title":"The circadian clock, light\/dark cycle and melatonin are differentially involved in the expression of daily and photoperiodic variations in mt(1) melatonin receptors in the Siberian and Syrian hamsters","volume":"74","author":"Schuster","year":"2001","journal-title":"Neuroendocrinology"},{"key":"B38","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/j.neuroscience.2006.03.037","article-title":"Glucocorticoid rhythms control the rhythm of expression of the clock protein, Period2, in oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats","volume":"140","author":"Segall","year":"2006","journal-title":"Neuroscience"},{"key":"B39","doi-asserted-by":"publisher","first-page":"211","DOI":"10.3109\/07420528.2014.963198","article-title":"Effects of adrenalectomy on daily gene expression rhythms in the rat suprachiasmatic and paraventricular hypothalamic nuclei and in white adipose tissue","volume":"32","author":"Su","year":"2015","journal-title":"Chronobiol. Int"},{"key":"B40","first-page":"471","article-title":"[Persistence of circadian rhythms of plasma ACTH and corticosterone after pinealectomy in sighted or blind rats]","volume":"297","author":"Szafarczyk","year":"1983","journal-title":"C. R. Seances Acad. Sci. III"},{"key":"B41","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1210\/en.2010-1260","article-title":"A circadian clock entrained by melatonin is ticking in the rat fetal adrenal","volume":"152","author":"Torres-Farfan","year":"2011","journal-title":"Endocrinology"},{"key":"B42","doi-asserted-by":"publisher","first-page":"4017","DOI":"10.1113\/jphysiol.2008.154351","article-title":"Evidence of a role for melatonin in fetal sheep physiology: direct actions of melatonin on fetal cerebral artery, brown adipose tissue and adrenal gland","volume":"586","author":"Torres-Farfan","year":"2008","journal-title":"J. Physiol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.exer.2012.08.009","article-title":"Melatonin: an underappreciated player in retinal physiology and pathophysiology","volume":"103","author":"Tosini","year":"2012","journal-title":"Exp. Eye Res"},{"key":"B44","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.1038\/sj.npp.1300254","article-title":"The pineal gland is critical for circadian Period1 expression in the striatum and for circadian cocaine sensitization in mice","volume":"28","author":"Uz","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"B45","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1210\/en.2007-1518","article-title":"Clock gene expression in adult primate suprachiasmatic nuclei and adrenal: is the adrenal a peripheral clock responsive to melatonin?","volume":"149","author":"Valenzuela","year":"2008","journal-title":"Endocrinology"}],"container-title":["Frontiers in Neuroscience"],"original-title":[],"deposited":{"date-parts":[[2015,6,19]],"date-time":"2015-06-19T12:16:10Z","timestamp":1434716170000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.frontiersin.org\/Neuroendocrine_Science\/10.3389\/fnins.2015.00190\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,27]]},"references-count":45,"URL":"https:\/\/doi.org\/10.3389\/fnins.2015.00190","relation":{},"ISSN":["1662-453X"],"issn-type":[{"value":"1662-453X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,27]]}}}