{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:40:39Z","timestamp":1791351639666,"version":"4.3.1"},"reference-count":197,"publisher":"Frontiers Media SA","funder":[{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002738","name":"Assistance Publique - H\u00f4pitaux de Paris","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"DOI":"10.3389\/fnins.2016.00256","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T11:56:56Z","timestamp":1467201416000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":184,"title":["New Insights in Anorexia Nervosa"],"prefix":"10.3389","volume":"10","author":[{"given":"Philip","family":"Gorwood","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinne","family":"Blanchet-Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Chartrel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne","family":"Duclos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Dechelotte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouna","family":"Hanachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serguei","family":"Fetissov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Godart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Melchior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Ramoz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Rovere-Jovene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Tolle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odile","family":"Viltart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Epelbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2016,6,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"3229","DOI":"10.1172\/JCI29867","article-title":"Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite","volume":"116","author":"Abizaid","year":"2006","journal-title":"J. Clin. Invest."},{"key":"B2","doi-asserted-by":"publisher","first-page":"640","DOI":"10.4161\/cib.17602","article-title":"A new theoretical approach to the functional meaning of sleep and dreaming in humans based on the maintenance of \u2018predictive psychic homeostasis","volume":"4","author":"Agnati","year":"2011","journal-title":"Commun. Integr. Biol."},{"key":"B3","doi-asserted-by":"crossref","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders, 5th Edn., (DSM-5)","author":"American Psychiatric Association","year":"2013"},{"key":"B4","doi-asserted-by":"publisher","first-page":"e7125","DOI":"10.1371\/journal.pone.0007125","article-title":"Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients","volume":"4","author":"Armougom","year":"2009","journal-title":"PLoS ONE"},{"key":"B5","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1136\/gut.2004.038737","article-title":"Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin","volume":"54","author":"Asakawa","year":"2005","journal-title":"Gut"},{"key":"B6","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.brainres.2009.09.106","article-title":"Lateral hypothalamic orexin\/hypocretin neurons: a role in reward-seeking and addiction","volume":"1314","author":"Aston-Jones","year":"2010","journal-title":"Brain Res."},{"key":"B7","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/7854_2010_78","article-title":"Serotonin: imaging findings in eating disorders","volume":"6","author":"Bailer","year":"2011","journal-title":"Curr. Top. Behav. Neurosci."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1016\/j.biopsych.2006.07.018","article-title":"Exaggerated 5-HT1A but normal 5-HT2A receptor activity in individuals ill with anorexia nervosa","volume":"61","author":"Bailer","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"B9","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.pscychresns.2012.06.010","article-title":"Interaction between serotonin transporter and dopamine D2\/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa","volume":"211","author":"Bailer","year":"2013","journal-title":"Psychiatry Res."},{"key":"B10","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1002\/eat.20937","article-title":"Amphetamine induced dopamine release increases anxiety in individuals recovered from anorexia nervosa","volume":"45","author":"Bailer","year":"2012","journal-title":"Int. J. Eat. Disord."},{"key":"B11","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/sj.mp.4001318","article-title":"Candidate genes for anorexia nervosa in the 1p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa","volume":"8","author":"Bergen","year":"2003","journal-title":"Mol. Psychiatry"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1038\/sj.npp.1300719","article-title":"Association of multiple DRD2 polymorphisms with anorexia nervosa","volume":"30","author":"Bergen","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"B13","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1016\/j.conb.2011.09.004","article-title":"Metabolic and hedonic drives in the neural control of appetite: who is the boss?","volume":"21","author":"Berthoud","year":"2011","journal-title":"Curr. Opin. Neurobiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1146\/annurev.nutr.19.1.41","article-title":"Development of food preferences","volume":"19","author":"Birch","year":"1999","journal-title":"Annu.Rev. Nutr."},{"key":"B15","volume-title":"Anorexia Nervosa; its History, Psychology, and Biology","author":"Bliss","year":"1960"},{"key":"B16","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.neuroscience.2009.08.009","article-title":"Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice","volume":"164","author":"Blum","year":"2009","journal-title":"Neuroscience"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1038\/mp.2013.187","article-title":"A genome-wide association study of anorexia nervosa","volume":"19","author":"Boraska","year":"2014","journal-title":"Mol. Psychiatry"},{"key":"B18","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1002\/eat.22325","article-title":"Parental mental illness and eating disorders in offspring","volume":"48","author":"Bould","year":"2015","journal-title":"Int. J. Eat. Disord."},{"key":"B19","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1056\/NEJM197410242911701","article-title":"Anorexia nervosa. Immaturity of the 24-hour luteinizing hormone secretory pattern","volume":"291","author":"Boyar","year":"1974","journal-title":"N. Engl. J. Med."},{"key":"B20","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1111\/j.1365-2265.2004.02011.x","article-title":"The endocrine response to acute ghrelin administration is blunted in patients with anorexia nervosa, a ghrelin hypersecretory state","volume":"60","author":"Broglio","year":"2004","journal-title":"Clin. Endocrinol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1002\/eat.20857","article-title":"Changes of orexin A plasma levels in girls with anorexia nervosa during eight weeks of realimentation","volume":"44","author":"Bronsky","year":"2011","journal-title":"Int. J. Eat. Disord."},{"key":"B22","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.biopsych.2006.04.007","article-title":"Further evidence of association of OPRD1 & HTR1D polymorphisms with susceptibility to anorexia nervosa","volume":"61","author":"Brown","year":"2007","journal-title":"Biol. Psychiatry"},{"key":"B23","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1002\/cne.21400","article-title":"Distribution of 26RFa binding sites and GPR103 mRNA in the central nervous system of the rat","volume":"503","author":"Bruzzone","year":"2007","journal-title":"J. Comp. Neurol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.physbeh.2010.03.009","article-title":"Role of orexin\/hypocretin in reward-seeking and addiction: implications for obesity","volume":"100","author":"Cason","year":"2010","journal-title":"Physiol. Behav."},{"key":"B25","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1016\/j.cpr.2005.04.012","article-title":"Personality and eating disorders: a decade in review","volume":"7","author":"Cassin","year":"2005","journal-title":"Clin. Psychol. Rev."},{"key":"B26","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.yfrne.2011.04.001","article-title":"The RFamide neuropeptide 26RFa and its role in the control of neuroendocrine functions","volume":"32","author":"Chartrel","year":"2011","journal-title":"Front. Neuroendocrinol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1126\/science.1135047","article-title":"Comment on \u201cObestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake","volume":"315","author":"Chartrel","year":"2007","journal-title":"Science"},{"key":"B28","doi-asserted-by":"publisher","first-page":"15247","DOI":"10.1073\/pnas.2434676100","article-title":"Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity","volume":"100","author":"Chartrel","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B29","first-page":"99","article-title":"Taste, facial expression and mother-infant interaction in early development","volume":"9","author":"Chiva","year":"1982","journal-title":"Baroda J. Nutr."},{"key":"B30","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1210\/er.2006-0034","article-title":"Studies on the physiological functions of the melanocortin system","volume":"27","author":"Cone","year":"2006","journal-title":"Endocr. Rev."},{"key":"B31","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/S0031-9384(03)00101-X","article-title":"A neurodevelopmental model for anorexia nervosa","volume":"79","author":"Connan","year":"2003","journal-title":"Physiol. Behav."},{"key":"B32","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.pscychresns.2005.10.006","article-title":"Hippocampal volume and cognitive function in anorexia nervosa","volume":"146","author":"Connan","year":"2006","journal-title":"Psychiatry Res."},{"key":"B33","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.psyneuen.2011.05.008","article-title":"Intestinal inflammation influences \u03b1-MSH reactive autoantibodies: relevance to food intake and body weight","volume":"37","author":"Coquerel","year":"2012","journal-title":"Psychoneuroendocrinology"},{"key":"B34","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/j.encep.2008.09.005","article-title":"[Social phobia in anorexia nervosa: evolution during the care]","volume":"35","author":"Coulon","year":"2009","journal-title":"Enc\u00e9phale"},{"key":"B35","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1002\/eat.20241","article-title":"Denial and minimization in adolescents with anorexia nervosa","volume":"39","author":"Couturier","year":"2006","journal-title":"Int. J. Eat. Disord."},{"key":"B36","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.biopsych.2011.05.028","article-title":"Increased neural processing of rewarding and aversive food stimuli in recovered anorexia nervosa","volume":"70","author":"Cowdrey","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"B37","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1038\/nrn3346","article-title":"Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour","volume":"13","author":"Cryan","year":"2012","journal-title":"Nat. Rev. Neurosci."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.2337\/diabetes.50.8.1714","article-title":"A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans","volume":"50","author":"Cummings","year":"2001","journal-title":"Diabetes"},{"key":"B39","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/S0010-440X(97)90927-5","article-title":"The prevalence of high-level exercise in the eating disorders: etiological implications","volume":"1","author":"Davis","year":"1997","journal-title":"Compr. Psychiatry"},{"key":"B40","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1677\/jme.1.01808","article-title":"Hypothalamic neuropeptide expression following chronic food restriction in sedentary and wheel-running rats","volume":"35","author":"de Rijke","year":"2005","journal-title":"J. Mol. Endocrinol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.nupar.2008.03.005","article-title":"Cons\u00e9quences digestives de l'anorexie mentale","volume":"21","author":"D\u00e9chelotte","year":"2007","journal-title":"Nutr. Clin. M\u00e9tabol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/j.biopsych.2014.12.016","article-title":"On Weight and waiting: delay discounting in anorexia nervosa pretreatment and posttreatment","volume":"78","author":"Decker","year":"2015","journal-title":"Biol. Psychiatry"},{"key":"B43","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1530\/EJE-12-0456","article-title":"Mechanisms in endocrinology: ghrelin: the differences between acyl- and des-acyl ghrelin","volume":"167","author":"Delhanty","year":"2012","journal-title":"Eur. J. Endocrinol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1159\/000346059","article-title":"Des-acyl ghrelin: a metabolically active peptide","volume":"25","author":"Delhanty","year":"2013","journal-title":"Endocr. Dev."},{"key":"B45","doi-asserted-by":"publisher","first-page":"e13320","DOI":"10.1371\/journal.pone.0013320","article-title":"Increased immune complexes of hypocretin autoantibodies in narcolepsy","volume":"5","author":"Deloumeau","year":"2010","journal-title":"PLoS ONE"},{"key":"B46","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.diabet.2013.11.002","article-title":"Central orchestration of peripheral nutrient partitioning and substrate utilization: implications for the metabolic syndrome","volume":"40","author":"Denis","year":"2014","journal-title":"Diabetes Metab."},{"key":"B47","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1016\/j.psyneuen.2012.03.007","article-title":"Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology","volume":"37","author":"Dinan","year":"2012","journal-title":"Psychoneuroendocrinology"},{"key":"B48","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.comppsych.2013.10.002","article-title":"Expressed emotion in anorexia nervosa: what is inside the \u201cblack box?\u201d","volume":"55","author":"Duclos","year":"2014","journal-title":"Compr. Psychiatry"},{"key":"B49","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.jpeds.2012.11.092","article-title":"A longitudinal investigation of nutrition and dietary patterns in children of mothers with eating disorders","volume":"163","author":"Easter","year":"2013","journal-title":"J. Pediatr."},{"key":"B50","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/S0140-6736(03)12378-1","article-title":"Eating disorders","volume":"361","author":"Fairburn","year":"2003","journal-title":"Lancet"},{"key":"B51","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1001\/archpsyc.63.1.82","article-title":"Perinatal factors and the risk of developing anorexia nervosa and bulimia nervosa","volume":"63","author":"Favaro","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"key":"B52","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/j.cmet.2015.08.003","article-title":"Leptin suppresses the rewarding effects of running via STAT3 signaling in dopamine neurons","volume":"6","author":"Fernandes","year":"2015","journal-title":"Cell Metab."},{"key":"B53","doi-asserted-by":"publisher","first-page":"17155","DOI":"10.1073\/pnas.222658699","article-title":"Autoantibodies against \u03b1-MSH, ACTH, and LHRH in anorexia and bulimia nervosa patients","volume":"99","author":"Fetissov","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B54","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.nut.2007.12.006","article-title":"Autoantibodies against appetite-regulating peptide hormones and neuropeptides: putative modulation by gut microflora","volume":"24","author":"Fetissov","year":"2008","journal-title":"Nutrition"},{"key":"B55","doi-asserted-by":"publisher","first-page":"14865","DOI":"10.1073\/pnas.0507204102","article-title":"Autoantibodies against neuropeptides are associated with psychological traits in eating disorders","volume":"102","author":"Fetissov","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B56","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jadohealth.2013.11.013","article-title":"Characteristics of avoidant\/restrictive food intake disorder in children and adolescents: a new disorder in DSM-5","volume":"55","author":"Fisher","year":"2014","journal-title":"J. Adolesc. Health"},{"key":"B57","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1176\/appi.ajp.2009.09010071","article-title":"A neural signature of anorexia nervosa in the ventral striatal reward system","volume":"167","author":"Fladung","year":"2010","journal-title":"Am. J. Psychiatry"},{"key":"B58","doi-asserted-by":"publisher","first-page":"e315","DOI":"10.1038\/tp.2013.88","article-title":"Role of the ventral striatum in developing anorexia nervosa","volume":"3","author":"Fladung","year":"2013","journal-title":"Transl. Psychiatry"},{"key":"B59","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.psychres.2012.12.018","article-title":"Fasting in mood disorders:neurobiology and effectiveness. A review of the literature","volume":"209","author":"Fond","year":"2013","journal-title":"Psychiatry Res."},{"key":"B60","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/S1471-4892(02)00013-9","article-title":"The MCH receptor family: feeding brain disorders?","volume":"3","author":"Forray","year":"2003","journal-title":"Curr. Opin. Pharmacol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1002\/cpp.626","article-title":"Eating disorders and multi-level models of emotion: an integrated model","volume":"16","author":"Fox","year":"2009","journal-title":"Clin. Psychol. Psychother."},{"key":"B62","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.biopsych.2005.05.003","article-title":"Increased dopamine D2\/D3 receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [11c]raclopride","volume":"58","author":"Frank","year":"2005","journal-title":"Biol. Psychiatry"},{"key":"B63","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1176\/appi.ajp.2013.12101294","article-title":"Alterations in brain structures related to taste reward circuitry in ill and recovered anorexia nervosa and in bulimia nervosa","volume":"170","author":"Frank","year":"2013","journal-title":"Am. J. Psychiatry"},{"key":"B64","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1002\/eat.20745","article-title":"Epigenetic dysregulation of dopaminergic genes in eating disorders","volume":"43","author":"Frieling","year":"2010","journal-title":"Int. J. Eat. Disord."},{"key":"B65","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1097\/DBP.0b013e31824a7baa","article-title":"The development of eating behavior","volume":"33","author":"Gahagan","year":"2012","journal-title":"J. Dev. Behav. Pediatr."},{"key":"B66","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.1210\/jc.2011-3396","article-title":"Orexigenic neuropeptide 26RFa: new evidence for an adaptive profile of appetite regulation in anorexia nervosa","volume":"97","author":"Galusca","year":"2012","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1016\/0140-6736(93)90768-C","article-title":"Pathogenesis of anorexia nervosa","volume":"341","author":"Garner","year":"1993","journal-title":"Lancet"},{"key":"B68","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/1098-108X(199303)13:2<171::AID-EAT2260130205>3.0.CO;2-L","article-title":"Anorexia nervosa \u201crestricters\u201d who purge: implications for subtyping anorexia nervosa","volume":"13","author":"Garner","year":"1993","journal-title":"Int. J. Eat. Disord."},{"key":"B69","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.psyneuen.2013.09.009","article-title":"Symptoms of depression and anxiety in anorexia nervosa: links with plasma tryptophan and serotonin metabolism","volume":"39","author":"Gauthier","year":"2014","journal-title":"Psychoneuroendocrinology"},{"key":"B70","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.euroneuro.2006.04.007","article-title":"Difference in susceptibility to activity-based anorexia in two inbred strains of mice","volume":"17","author":"Gelegen","year":"2007","journal-title":"Eur. Neuropsychopharmacol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.1523\/JNEUROSCI.1714-04.2005","article-title":"The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance","volume":"25","author":"Georgescu","year":"2005","journal-title":"J. Neurosci."},{"key":"B72","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1210\/jc.2009-2196","article-title":"Ghrelin and obestatin circadian levels differentiate bingeing-purging from restrictive anorexia nervosa","volume":"2010","author":"Germain","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"B73","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1016\/j.psyneuen.2008.10.001","article-title":"Ghrelin\/obestatin ratio in two populations with low bodyweight: constitutional thinness and anorexia nervosa","volume":"34","author":"Germain","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"B74","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1093\/ajcn\/85.4.967","article-title":"Constitutional thinness and lean anorexia nervosa display opposite concentrations of peptide YY, glucagon-like peptide 1, ghrelin, and leptin","volume":"85","author":"Germain","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"key":"B75","doi-asserted-by":"publisher","first-page":"53","DOI":"10.4236\/ojepi.2013.32009","article-title":"Epidemiology of anorexia nervosa in a French community-based sample of 39,542 adolescents","volume":"3","author":"Godart","year":"2013","journal-title":"Open J. Epidemiol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.jad.2006.06.023","article-title":"Depression and eating disorders: a review","volume":"97","author":"Godart","year":"2007","journal-title":"J. Affect. Disord."},{"key":"B77","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/eat.10096","article-title":"Comorbidity between eating disorders and anxiety disorders: a review","volume":"32","author":"Godart","year":"2002","journal-title":"Int. J. Eat. Disord."},{"key":"B78","doi-asserted-by":"publisher","first-page":"272","DOI":"10.3945\/ajcn.111.020131","article-title":"Intact sensory function in anorexia nervosa","volume":"95","author":"Goldzak-Kunik","year":"2012","journal-title":"Am. J. Clin. Nutr."},{"key":"B79","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.bcp.2007.07.030","article-title":"Neurobiology of addiction: an integrative review","volume":"75","author":"Goodman","year":"2008","journal-title":"Biochem. Pharmacol"},{"key":"B80","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1093\/aje\/kwt445","article-title":"Associations between birth characteristics and eating disorders across the life course: findings from 2 million males and females born in Sweden, 1975-1998","volume":"179","author":"Goodman","year":"2014","journal-title":"Am. J. Epidemiol"},{"key":"B81","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/ajcn\/64.3.267","article-title":"A double-blind, placebo-controlled trial of the effect of fluoxetine on dietary intake in overweight women with and without binge-eating disorder","volume":"64","author":"Greeno","year":"1996","journal-title":"Am. J. Clin. Nutr."},{"key":"B82","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/S0140-6736(00)48519-3","article-title":"Anorexia nervosa","volume":"1","author":"Gull","year":"1888","journal-title":"Lancet"},{"key":"B83","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1037\/h0062565","article-title":"Elevation of activity level in the rat following transition from ad libitum to restricted feeding","volume":"46","author":"Hall","year":"1953","journal-title":"J. Comp. Physiol. Psychol."},{"key":"B84","doi-asserted-by":"publisher","first-page":"S68","DOI":"10.1016\/S0261-5614(13)60168-5","article-title":"Pilot study of intestinal microbiota diversity in severe malnourished patients with anorexia nervosa","volume":"32","author":"Hanachi","year":"2013","journal-title":"Clin. Nutr."},{"key":"B85","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1016\/j.molimm.2011.02.002","article-title":"Influence of gut microbiota on mouse B2 B cell ontogeny and function","volume":"48","author":"Hansson","year":"2011","journal-title":"Mol. Immunol."},{"key":"B86","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/S0896-6273(01)00293-8","article-title":"Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity","volume":"30","author":"Hara","year":"2001","journal-title":"Neuron"},{"key":"B87","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1192\/bjp.173.1.11","article-title":"Excess mortality of mental disorder","volume":"173","author":"Harris","year":"1998","journal-title":"Br. J. Psychiatry"},{"key":"B88","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1038\/nature04071","article-title":"A role for lateral hypothalamic orexin neurons in reward seeking","volume":"437","author":"Harris","year":"2005","journal-title":"Nature"},{"key":"B89","doi-asserted-by":"publisher","first-page":"679","DOI":"10.7150\/ijms.8.679","article-title":"Anorexia nervosa: a unified neurological perspective","volume":"8","author":"Hasan","year":"2011","journal-title":"Int. J. Med. Sci."},{"key":"B90","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1111\/j.1365-2826.2010.02019.x","article-title":"The ghrelin\/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake","volume":"22","author":"Hassouna","year":"2010","journal-title":"J. Neuroendocrinol."},{"key":"B91","doi-asserted-by":"publisher","first-page":"e51135","DOI":"10.1371\/journal.pone.0051135","article-title":"A natural variant of obestatin, Q90L, inhibits ghrelin's action on food intake and GH secretion and targets NPY and GHRH neurons in mice","volume":"7","author":"Hassouna","year":"2012","journal-title":"PLoS ONE"},{"key":"B92","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.jadohealth.2013.08.007","article-title":"Adolescents' level of eating psychopathology is related to perceptions of their parents' current feeding practices","volume":"54","author":"Haycraft","year":"2014","journal-title":"J. Adolesc. Health"},{"key":"B93","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/j.1468-2850.2011.01250.x","article-title":"Anorexia nervosa as a disorder of emotion dysregulation: evidence and treatment implications","volume":"18","author":"Haynos","year":"2011","journal-title":"Clin. Psychol."},{"key":"B94","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1007\/s00421-010-1558-8","article-title":"Polymorphisms in the calcineurin genes are associated with the training responsiveness of cardiac phenotypes in Chinese young adults","volume":"110","author":"He","year":"2010a","journal-title":"Eur. J. Appl. Physiol."},{"key":"B95","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1007\/s00421-010-1361-6","article-title":"Are calcineurin genes associated with endurance phenotype traits?","volume":"109","author":"He","year":"2010b","journal-title":"Eur. J. Appl. Physiol."},{"key":"B96","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1016\/S0140-6736(95)91955-4","article-title":"Plasma concentrations of obese protein in anorexia nervosa","volume":"346","author":"Hebebrand","year":"1995","journal-title":"Lancet"},{"key":"B97","doi-asserted-by":"publisher","first-page":"S177","DOI":"10.1007\/s00406-011-0246-y","article-title":"Aetiology of anorexia nervosa: from a \u201cpsychosomatic family model\u201d to a neuropsychiatric disorder?","volume":"261","author":"Herpertz-Dahlmann","year":"2011","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"B98","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/j.psychres.2014.05.054","article-title":"Risk factors across the eating disorders","volume":"220","author":"Hilbert","year":"2014","journal-title":"Psychiatry Res."},{"key":"B99","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.2044-8260.1998.tb01275.x","article-title":"Mothers, daughters and dieting: investigating the transmission of weight control","volume":"37","author":"Hill","year":"1998","journal-title":"Br. J. Clin. Psychol."},{"key":"B100","doi-asserted-by":"publisher","first-page":"15799","DOI":"10.1074\/jbc.M609796200","article-title":"Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism","volume":"282","author":"Holst","year":"2007","journal-title":"J. Biol. Chem."},{"key":"B101","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1507\/endocrj.K09E-168","article-title":"Ghrelin increases hunger and food intake in patients with restricting-type Anorexia Nervosa: a pilot study","volume":"56","author":"Hotta","year":"2009","journal-title":"Endocr. J."},{"key":"B102","doi-asserted-by":"publisher","first-page":"2159","DOI":"10.1016\/j.peptides.2008.09.014","article-title":"Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats","volume":"29","author":"Inhoff","year":"2008","journal-title":"Peptides"},{"key":"B103","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1038\/sj.mp.4000944","article-title":"Eating behavior in anorexia nervosa\u2013an excess of both orexigenic and anorexigenic signalling?","volume":"6","author":"Inui","year":"2001","journal-title":"Mol. Psychiatry"},{"key":"B104","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.physbeh.2004.01.009","article-title":"Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in rats","volume":"81","author":"Ishii","year":"2004","journal-title":"Physiol. Behav."},{"key":"B105","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000328580","article-title":"Etiological role of childhood emotional trauma and neglect in adolescent anorexia nervosa: a cross-sectional questionnaire analysis","volume":"45","author":"Jaite","year":"2012","journal-title":"Psychopathology"},{"key":"B106","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.regpep.2011.02.005","article-title":"Plasma levels of leptin and orexin A in the restrictive type of anorexia nervosa","volume":"168","author":"Janas-Kozik","year":"2011","journal-title":"Regul. Pept."},{"key":"B107","volume-title":"Les Addictions Monographie de Psychopathologie Edition.","author":"Jeammet","year":"1991"},{"key":"B108","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1016\/j.clnu.2013.11.006","article-title":"Alteration of intestinal barrier function during activity-based anorexia in mice","volume":"33","author":"J\u00e9sus","year":"2014","journal-title":"Clin. Nutr."},{"key":"B109","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1210\/me.2005-0084","article-title":"Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor\/dopamine receptor subtype 1 heterodimers","volume":"20","author":"Jiang","year":"2006","journal-title":"Mol. Endocrinol."},{"key":"B110","first-page":"257","volume-title":"Eat disord","author":"Kaye","year":"2003"},{"key":"B111","first-page":"433","article-title":"Contribution of CNS neuropeptide (NPY, CRH, and beta-endorphin) alterations to psychophysiological abnormalities in anorexia nervosa","volume":"25","author":"Kaye","year":"1989","journal-title":"Psychopharmacol. Bull."},{"key":"B112","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/nrn2682","article-title":"New insights into symptoms and neurocircuit function of anorexia nervosa","volume":"10","author":"Kaye","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"B113","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1176\/ajp.139.5.643","article-title":"Cerebrospinal fluid opioid activity in anorexia nervosa","volume":"139","author":"Kaye","year":"1982","journal-title":"Am. J. Psychiatry"},{"key":"B114","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.neuron.2011.10.038","article-title":"Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism","volume":"73","author":"Kern","year":"2012","journal-title":"Neuron"},{"key":"B115","doi-asserted-by":"publisher","first-page":"3213","DOI":"10.1007\/s10620-012-2197-1","article-title":"Methanobrevibacter smithii is the predominant methanogen in patients with constipation-predominant IBS and methane on breath","volume":"57","author":"Kim","year":"2012","journal-title":"Dig. Dis. Sci."},{"key":"B116","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/j.yhbeh.2013.02.019","article-title":"Puberty as a critical risk period for eating disorders: a review of human and animal studies","volume":"64","author":"Klump","year":"2013","journal-title":"Horm. Behav."},{"key":"B117","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1152\/physrev.00012.2004","article-title":"Ghrelin: structure and function","volume":"85","author":"Kojima","year":"2005","journal-title":"Physiol. Rev."},{"key":"B118","first-page":"2656","article-title":"Ghrelin is a growth-hormone-releasing acylated peptide from stomach","volume":"40","author":"Kojima","year":"1999","journal-title":"Nature"},{"key":"B119","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1097\/00004583-200112000-00014","article-title":"Longitudinal relationships between childhood, adolescent, and adult eating disorders","volume":"40","author":"Kotler","year":"2001","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"B120","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1177\/0884533611436116","article-title":"Effects of gut microbes on nutrient absorption and energy regulation","volume":"27","author":"Krajmalnik-Brown","year":"2012","journal-title":"Nutr. Clin. Pract."},{"key":"B121","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.bbrc.2006.09.141","article-title":"Obestatin does not activate orphan G protein-coupled receptor GPR39","volume":"351","author":"Lauwers","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B122","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1152\/physrev.00005.2009","article-title":"Reward processing by the opioid system in the brain","volume":"89","author":"Le Merrer","year":"2009","journal-title":"Physiol. Rev."},{"key":"B123","doi-asserted-by":"publisher","first-page":"R1105","DOI":"10.1152\/ajpregu.00076.2011","article-title":"Involvement of the opioid system in the orexigenic and hedonic effects of melanin-concentrating hormone","volume":"301","author":"Lopez","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"B124","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1002\/eat.22189","article-title":"Are food restriction and pressure-to-eat parenting practices associated with adolescent disordered eating behaviors?","volume":"47","author":"Loth","year":"2014","journal-title":"Int. J. Eat. Disord."},{"key":"B125","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.npep.2013.10.017","article-title":"Effects of rabbit anti-\u03b1-melanocyte-stimulating hormone (\u03b1-MSH) immunoglobulins on \u03b1-MSH signaling related to food intake control","volume":"48","author":"Lucas","year":"2014","journal-title":"Neuropeptides"},{"key":"B126","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1097\/00004583-199001000-00017","article-title":"Early childhood eating behaviors and adolescent eating disorders","volume":"29","author":"Marchi","year":"1990","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"B127","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/0149-7634(79)90005-8","article-title":"Beta-endorphin and endoloxone: Hormones for the autonomic nervous system for the conservation or expenditure of bodily resources","volume":"3","author":"Margules","year":"1979","journal-title":"Neurosci. Behav. Rev."},{"key":"B128","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.1016\/S0024-3205(97)00133-1","article-title":"Endogenous codeine and morphine in anorexia and bulimia nervosa","volume":"60","author":"Marrazzi","year":"1997","journal-title":"Life Sci."},{"key":"B129","doi-asserted-by":"publisher","first-page":"3240","DOI":"10.1073\/pnas.052706899","article-title":"Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism","volume":"99","author":"Marsh","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B130","doi-asserted-by":"publisher","first-page":"E241","DOI":"10.1152\/ajpendo.00340.2014","article-title":"Physical activity: benefit or weakness in metabolic adaptations in a mouse model of chronic food restriction?","volume":"308","author":"M\u00e9quinion","year":"2015a","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"68","key":"B131","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2015.00068","article-title":"The use of animal models to decipher physiological and neurobiological alterations of anorexia nervosa patients. nervosa patients","volume":"6","author":"M\u00e9quinion","year":"2015b","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"15","key":"B132","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2013.00015","article-title":"Ghrelin: central and peripheral implications in anorexia nervosa","volume":"26","author":"M\u00e9quinion","year":"2013","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"B133","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.jpeds.2008.07.003","article-title":"Infant feeding and weight in the first year of life in babies of women with eating disorders","volume":"154","author":"Micali","year":"2009","journal-title":"J. Pediatr."},{"key":"B134","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1002\/eat.22216","article-title":"The effects of maternal eating disorders on offspring childhood and early adolescent psychiatric disorders","volume":"47","author":"Micali","year":"2014","journal-title":"Int. J. Eat. Disord."},{"key":"B135","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1111\/j.1469-7610.2010.02341.x","article-title":"Maternal eating disorders and infant feeding difficulties: maternal and child mediators in a longitudinal general population study","volume":"52","author":"Micali","year":"2011","journal-title":"J. Child Psychol. Psychiatry"},{"key":"B136","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1210\/jc.2005-2304","article-title":"Ghrelin has partial or no effect on appetite, growth hormone, prolactin, and cortisol release in patients with anorexia nervosa","volume":"91","author":"Miljic","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"B137","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1038\/ijo.2013.20","article-title":"Correlation between body mass index and gut concentrations of Lactobacillus reuteri, Bifidobacterium animalis, Methanobrevibacter smithii and Escherichia coli","volume":"37","author":"Million","year":"2013","journal-title":"Int. J. Obes"},{"issue":"228","key":"B138","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2011.00228","article-title":"Gut microbiota of healthy and malnourished children in bangladesh","volume":"2","author":"Monira","year":"2011","journal-title":"Front. Microbiol."},{"key":"B139","doi-asserted-by":"publisher","first-page":"2916","DOI":"10.1210\/en.2005-1580","article-title":"RFamide peptide QRFP43 causes obesity with hyperphagia and reduced thermogenesis in mice","volume":"147","author":"Moriya","year":"2006","journal-title":"Endocrinology"},{"key":"B140","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1751-0759-2-5","article-title":"Psychological and weight-related characteristics of patients with anorexia nervosa-restricting type who later develop bulimia nervosa","volume":"2","author":"Nishumira","year":"2008","journal-title":"Biopsychosoc. Med."},{"key":"B141","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1002\/eat.22217","article-title":"Exploring avoidant\/restrictive food intake disorder in eating disordered patients: a descriptive study","volume":"47","author":"Norris","year":"2014","journal-title":"Int. J. Eat. Disord."},{"key":"B142","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1530\/eje.0.1450669","article-title":"Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa","volume":"145","author":"Otto","year":"2001","journal-title":"Eur. J. Endocrinol."},{"key":"B143","doi-asserted-by":"publisher","first-page":"G610","DOI":"10.1152\/ajpgi.00321.2007","article-title":"Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure","volume":"294","author":"Pfluger","year":"2008","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"B144","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1002\/ajmg.b.31082","article-title":"Association study of 182 candidate genes in anorexia nervosa","volume":"153B","author":"Pinheiro","year":"2010","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"B145","doi-asserted-by":"publisher","first-page":"755","DOI":"10.3945\/ajcn.2008.27056","article-title":"Systematic review and meta-analysis of the baseline concentrations and physiologic responses of gut hormones to food in eating disorders","volume":"89","author":"Prince","year":"2009","journal-title":"Am. J. Clin. Nutr."},{"key":"B146","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1038\/380243a0","article-title":"A role for melanin-concentrating hormone in the central regulation of feeding behaviour","volume":"380","author":"Qu","year":"1996","journal-title":"Nature"},{"key":"B147","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1002\/eat.22323","article-title":"Prenatal and perinatal factors in eating disorders: A descriptive review","volume":"47","author":"Raevuori","year":"2014","journal-title":"Int. J. Eat. Disord"},{"key":"B148","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1002\/eat.20508","article-title":"Influence of overanxious disorder of childhood on the expression of anorexia nervosa","volume":"41","author":"Raney","year":"2008","journal-title":"Int. J. Eat. Disord."},{"key":"B149","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.appet.2011.12.016","article-title":"Links between maternal feeding practices and children's eating difficulties","volume":"58","author":"Rigal","year":"2012","journal-title":"Appetite"},{"key":"B150","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1037\/h0025205","article-title":"Self-starvation of rats living in activity wheels on a restricted feeding schedule","volume":"64","author":"Routtenberg","year":"1967","journal-title":"J. Comp. Physiol. Psychol."},{"key":"B151","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/S0092-8674(00)80949-6","article-title":"Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior","volume":"92","author":"Sakurai","year":"1998","journal-title":"Cell"},{"key":"B152","doi-asserted-by":"publisher","first-page":"10643","DOI":"10.1073\/pnas.0704189104","article-title":"Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut","volume":"104","author":"Samuel","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B153","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1073\/pnas.1212137110","article-title":"Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons","volume":"110","author":"Schaeffer","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B154","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.physbeh.2010.03.016","article-title":"Neurobiology of hyperactivity and reward: agreeable restlessness in anorexia nervosa","volume":"100","author":"Scheurink","year":"2010","journal-title":"Physiol. Behav."},{"key":"B155","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1348\/014466505X53902","article-title":"Anorexia nervosa: valued and visible. A cognitive-interpersonal maintenance model and its implications for research and practice","volume":"45","author":"Schmidt","year":"2006","journal-title":"Br. J. Clin. Psychol."},{"key":"B156","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1038\/npp.2015.287","article-title":"Daily exposure to sucrose impairs subsequent learning about food cues: a role for alterations in ghrelin signaling and dopamine D2 receptors","volume":"41","author":"Sharpe","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"B157","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1038\/25341","article-title":"Mice lacking melanin-concentrating hormone are hypophagic and lean","volume":"396","author":"Shimada","year":"1998","journal-title":"Nature"},{"key":"B158","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.psyneuen.2008.08.021","article-title":"Regulation of feeding and anxiety by \u03b1-MSH reactive autoantibodies","volume":"34","author":"Sinno","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"B159","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.neuropharm.2013.06.004","article-title":"Divergent circuitry underlying food reward and intake effects of ghrelin: dopaminergic VTA-accumbens projection mediates ghrelin's effect on food reward but not food intake","volume":"73","author":"Skibicka","year":"2013","journal-title":"Neuropharmacology"},{"key":"B160","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1126\/science.1229000","article-title":"Gut microbiomes of Malawian twin pairs discordant for kwashiorkor","volume":"339","author":"Smith","year":"2013","journal-title":"Science"},{"key":"B161","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1176\/appi.ajp.157.3.393","article-title":"Controlled family study of anorexia nervosa and bulimia nervosa: evidence of shared liability and transmission of partial syndromes","volume":"157","author":"Strober","year":"2000","journal-title":"Am. J. Psychiatry"},{"key":"B162","doi-asserted-by":"publisher","first-page":"7973","DOI":"10.1128\/MCB.23.22.7973-7981.2003","article-title":"Deletion of ghrelin impairs neither growth nor appetite","volume":"23","author":"Sun","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"B163","doi-asserted-by":"publisher","first-page":"4679","DOI":"10.1073\/pnas.0305930101","article-title":"Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor","volume":"101","author":"Sun","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B164","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1016\/j.psyneuen.2010.05.005","article-title":"Do thyroid hormones mediate the effects of starvation on mood in adolescent girls with eating disorders?","volume":"35","author":"Swenne","year":"2010","journal-title":"Psychoneuroendocrinology"},{"key":"B165","doi-asserted-by":"publisher","first-page":"7438","DOI":"10.1073\/pnas.0602371103","article-title":"A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice","volume":"103","author":"Takayasu","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B166","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1002\/eat.22302","article-title":"Attachment and eating disorders: A review of current research","volume":"47","author":"Tasca","year":"2014","journal-title":"Int. J. Eat. Disord."},{"key":"B167","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1016\/j.chiabu.2013.03.004","article-title":"Attachment insecurity mediates the relationship between childhood trauma and eating disorder psychopathology in a clinical sample: a structural equation model","volume":"37","author":"Tasca","year":"2013","journal-title":"Child Abuse Negl."},{"key":"B168","doi-asserted-by":"publisher","first-page":"e458","DOI":"10.1038\/tp.2014.98","article-title":"Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide \u03b1-MSH, at the origin of eating disorders","volume":"4","author":"Tennoune","year":"2014","journal-title":"Transl. Psychiatry"},{"key":"B169","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.nut.2011.01.002","article-title":"Ghrelin reactive autoantibodies in restrictive anorexia nervosa","volume":"27","author":"Terashi","year":"2011","journal-title":"Nutrition"},{"key":"B170","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1159\/000054620","article-title":"In vivo and in vitro effects of ghrelin\/motilin-related peptide on growth hormone secretion in the rat","volume":"73","author":"Tolle","year":"2001","journal-title":"Neuroendocrinology"},{"key":"B171","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1053\/gast.2000.9371","article-title":"Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide","volume":"119","author":"Tomasetto","year":"2000","journal-title":"Gastroenterology"},{"key":"B172","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1002\/erv.2303","article-title":"Central and peripheral peptides regulating eating behaviour and energy homeostasis in anorexia nervosa and bulimia nervosa: a literature review","volume":"22","author":"Tortorella","year":"2014","journal-title":"Eur. Eat. Disord. Rev."},{"key":"B173","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.psychres.2010.04.005","article-title":"Subclinical eating disorders and their comorbidity with mood and anxiety disorders in adolescent girls","volume":"185","author":"Touchette","year":"2011","journal-title":"Psychiatry Res."},{"key":"B174","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.socscimed.2011.09.036","article-title":"How does the social environment \u2018get into the mind\u2019? Epigenetics at the intersection of social and psychiatric epidemiology","volume":"74","author":"Toyokawa","year":"2012","journal-title":"Soc. Sci. Med."},{"key":"B175","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1146\/annurev-clinpsy-050212-185546","article-title":"The genetics of eating disorders","volume":"9","author":"Trace","year":"2013","journal-title":"Annu. Rev. Clin. Psychol."},{"key":"B176","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/S0140-6736(09)61748-7","article-title":"Eating disorders","volume":"375","author":"Treasure","year":"2010","journal-title":"Lancet"},{"key":"B177","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/2050-2974-1-13","article-title":"The cognitive-interpersonal maintenance model of anorexia nervosa revisited: a summary of the evidence for cognitive, socio-emotional and interpersonal predisposing and perpetuating factors","volume":"1","author":"Treasure","year":"2013","journal-title":"J. Eat. Disord."},{"key":"B178","doi-asserted-by":"publisher","DOI":"10.1111\/eip.12170","article-title":"Has the time come for a staging model to map the course of eating disorders from high risk to severe enduring illness? An examination of the evidence","author":"Treasure","year":"2014","journal-title":"Early Interv. Psychiatry."},{"key":"B179","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1056\/NEJMoa1202851","article-title":"Antibiotics as part of the management of severe acute malnutrition","volume":"368","author":"Trehan","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"B180","doi-asserted-by":"publisher","first-page":"327","DOI":"10.3109\/15622975.2013.860467","article-title":"Decreased whole-blood global DNA methylation is related to serum hormones in anorexia nervosa adolescents","volume":"15","author":"Tremolizzo","year":"2014","journal-title":"World J. Biol. Psychiatry"},{"issue":"121","key":"B181","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00121","article-title":"Ghrelin and eating behavior: evidence and insights from genetically-modified mouse models","volume":"7","author":"Uchida","year":"2013","journal-title":"Front. Neurosci."},{"key":"B182","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1111\/j.1749-6632.2010.05509.x","article-title":"Translational research of ghrelin","volume":"1200","author":"Ueno","year":"2010","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"B183","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0031-9384(97)00144-3","article-title":"Separation as a new animal model for self-induced weight loss","volume":"62","author":"van Leeuwen","year":"1997","journal-title":"Physiol. Behav."},{"key":"B184","volume-title":"Les Nouvelles Addictions","author":"Venisse","year":"1991"},{"key":"B185","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.euroneuro.2010.06.005","article-title":"Acute and chronic suppression of the central ghrelin signaling system reveals a role in food anticipatory activity","volume":"21","author":"Verhagen","year":"2011","journal-title":"Eur. Neuropsychopharmacol."},{"key":"B186","doi-asserted-by":"publisher","first-page":"1842","DOI":"10.1176\/appi.ajp.2007.07040575","article-title":"Altered reward processing in women recovered from anorexia nervosa","volume":"164","author":"Wagner","year":"2007","journal-title":"Am. J. Psychiatry"},{"key":"B187","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1038\/mp.2010.107","article-title":"A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa","volume":"16","author":"Wang","year":"2011","journal-title":"Mol. Psychiatry"},{"key":"B188","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.jsb.2012.05.002","article-title":"Chaperone networks in protein disaggregation and prion propagation","volume":"179","author":"Winkler","year":"2012","journal-title":"J. Struct. Biol."},{"key":"B189","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/S0169-328X(98)00320-9","article-title":"Down regulation of the prepro-orexin gene expression in genetically obese mice","volume":"65","author":"Yamamoto","year":"1999","journal-title":"Brain Res. Mol. Brain Res."},{"key":"B190","doi-asserted-by":"publisher","first-page":"e103775","DOI":"10.1371\/journal.pone.0103775","article-title":"Long-term physiological alterations and recovery in a mouse model of separation associated with time-restricted feeding: a tool to study anorexia nervosa related consequences","volume":"9","author":"Zgheib","year":"2014","journal-title":"PLoS ONE"},{"key":"B191","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1126\/science.1117255","article-title":"Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake","volume":"310","author":"Zhang","year":"2005","journal-title":"Science"},{"key":"B192","doi-asserted-by":"publisher","first-page":"15868","DOI":"10.1073\/pnas.1011116107","article-title":"Ghrelin secretion stimulated by {beta}1-adrenergic receptors in cultured ghrelinoma cells and in fasted mice","volume":"107","author":"Zhao","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B193","doi-asserted-by":"publisher","first-page":"11075","DOI":"10.1523\/JNEUROSCI.3542-07.2007","article-title":"Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens","volume":"27","author":"Zheng","year":"2007","journal-title":"J. Neurosci."},{"key":"B194","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1002\/erv.2197","article-title":"Processing of food, body and emotional stimuli in anorexia nervosa: a systematic review and meta-analysis of functional magnetic resonance imaging studies","volume":"20","author":"Zhu","year":"2012","journal-title":"Eur. Eat. Disord. Rev."},{"key":"B195","doi-asserted-by":"publisher","first-page":"3564","DOI":"10.1172\/JCI26002","article-title":"Mice lacking ghrelin receptors resist the development of diet-induced obesity","volume":"115","author":"Zigman","year":"2005","journal-title":"J. Clin. Invest."},{"key":"B196","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/S0140-6736(99)05363-5","article-title":"Long-term prognosis in anorexia nervosa: lessons from a 21-year follow-up study","volume":"355","author":"Zipfel","year":"2000","journal-title":"Lancet"},{"key":"B197","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1210\/en.2006-1231","article-title":"Obestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodents","volume":"148","author":"Zizzari","year":"2007","journal-title":"Endocrinology"}],"container-title":["Frontiers in Neuroscience"],"original-title":[],"deposited":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T07:06:19Z","timestamp":1568099179000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/Article\/10.3389\/fnins.2016.00256\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,29]]},"references-count":197,"URL":"https:\/\/doi.org\/10.3389\/fnins.2016.00256","relation":{},"ISSN":["1662-453X"],"issn-type":[{"value":"1662-453X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,29]]}}}