{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:49:06Z","timestamp":1790610546496,"version":"4.1.0"},"reference-count":167,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T00:00:00Z","timestamp":1567382400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006254","name":"Ruhr-Universit\u00e4t Bochum","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006254","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011961","name":"Stiftung zur F\u00f6rderung der Erforschung von Ersatz- und Erg\u00e4nzungsmethoden zur Einschr\u00e4nkung von Tierversuchen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011961","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"DOI":"10.3389\/fnins.2019.00931","type":"journal-article","created":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T13:07:22Z","timestamp":1567429642000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Immune Mediated Degeneration and Possible Protection in Glaucoma"],"prefix":"10.3389","volume":"13","author":[{"given":"Teresa","family":"Tsai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Reinehr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana M.","family":"Maliha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie C.","family":"Joachim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,9,2]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1038\/nn.2887","article-title":"Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool.","volume":"14","author":"Ajami","year":"2011","journal-title":"Nat. Neurosci."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scr.2019.101491","article-title":"Accelerated photoreceptor differentiation of hiPSC-derived retinal organoids by contact co-culture with retinal pigment epithelium.","volume":"39","author":"Akhtar","year":"2019","journal-title":"Stem Cell Res."},{"key":"B3","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.preteyeres.2011.11.002","article-title":"The molecular basis of retinal ganglion cell death in glaucoma.","volume":"31","author":"Almasieh","year":"2012","journal-title":"Prog. Retin. Eye Res."},{"key":"B4","doi-asserted-by":"publisher","first-page":"2636","DOI":"10.1016\/j.visres.2009.04.008","article-title":"Naturally occurring animal models with outer retina phenotypes.","volume":"49","author":"Baehr","year":"2009","journal-title":"Vision Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/s00347-014-3100-6","article-title":"[Complement activation after induction of ocular hypertension in an animal model].","volume":"112","author":"Becker","year":"2015","journal-title":"Ophthalmologe"},{"key":"B6","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.preteyeres.2013.02.003","article-title":"Does autoimmunity play a part in the pathogenesis of glaucoma?","volume":"36","author":"Bell","year":"2013","journal-title":"Prog. Retin. Eye Res."},{"key":"B7","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1111\/jnc.13765","article-title":"Neuroprotective effects of antibodies on retinal ganglion cells in an adolescent retina organ culture.","volume":"139","author":"Bell","year":"2016","journal-title":"J. Neurochem."},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-015-0044-9","article-title":"Protective effect of 14-3-3 antibodies on stressed neuroretinal cells via the mitochondrial apoptosis pathway.","volume":"15","author":"Bell","year":"2015","journal-title":"BMC Ophthalmol."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057557","article-title":"Analysis of complement proteins in retina and sera of glaucoma patients.","volume":"51","author":"Boehm","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.bbi.2011.07.241","article-title":"New insights into autoantibody profiles from immune privileged sites in the eye: a glaucoma study.","volume":"26","author":"Boehm","year":"2012","journal-title":"Brain Behav. Immun."},{"key":"B11","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1111\/jnc.14070","article-title":"Involvement of microglia in early axoglial alterations of the optic nerve induced by experimental glaucoma.","volume":"142","author":"Bordone","year":"2017","journal-title":"J. Neurochem."},{"key":"B12","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1016\/j.ymthe.2018.08.017","article-title":"Complement C3-targeted gene therapy restricts onset and progression of neurodegeneration in chronic mouse glaucoma.","volume":"26","author":"Bosco","year":"2018","journal-title":"Mol. Ther."},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0043602","article-title":"Early reduction of microglia activation by irradiation in a model of chronic glaucoma.","volume":"7","author":"Bosco","year":"2012","journal-title":"PLoS One"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1167\/iovs.07-1337","article-title":"Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA\/2J mouse model of glaucoma.","volume":"49","author":"Bosco","year":"2008","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1002\/cne.22516","article-title":"Early microglia activation in a mouse model of chronic glaucoma.","volume":"519","author":"Bosco","year":"2011","journal-title":"J. Comp. Neurol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"3626","DOI":"10.1167\/iovs.15-18999R2","article-title":"Specific inner retinal layer cell damage in an autoimmune glaucoma model is induced by GDNF with or without HSP27.","volume":"57","author":"Casola","year":"2016","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B17","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1007\/s12031-014-0485-2","article-title":"S100 alone has the same destructive effect on retinal ganglion cells as in combination with HSP 27 in an autoimmune glaucoma model.","volume":"56","author":"Casola","year":"2015","journal-title":"J. Mol. Neurosci."},{"key":"B18","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1111\/j.1442-9071.2006.01146.x","article-title":"Possible role of excitotoxicity in the pathogenesis of glaucoma.","volume":"34","author":"Casson","year":"2006","journal-title":"Clin. Exp. Ophthalmol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1111\/j.1442-9071.2012.02773.x","article-title":"Definition of glaucoma: clinical and experimental concepts.","volume":"40","author":"Casson","year":"2012","journal-title":"Clin. Exp. Ophthalmol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1016\/j.ophtha.2011.11.003","article-title":"Glaucoma 2.0: neuroprotection, neuroregeneration, neuroenhancement.","volume":"119","author":"Chang","year":"2012","journal-title":"Ophthalmology"},{"key":"B21","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/s0006-8993(98)00212-1","article-title":"MK801-a neuroprotectant in rat hypertensive eyes.","volume":"792","author":"Chaudhary","year":"1998","journal-title":"Brain Res."},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2019.102045","article-title":"Multipotent stem cell-derived retinal ganglion cells in 3D culture as tools for neurotrophic factor gene delivery system development.","volume":"21","author":"Chen","year":"2019","journal-title":"Nanomedicine"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05681-9","article-title":"Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma.","volume":"9","author":"Chen","year":"2018","journal-title":"Nat. Commun."},{"key":"B24","doi-asserted-by":"publisher","first-page":"750","DOI":"10.3980\/j.issn.2222-3959.2012.06.18","article-title":"High myopia as a risk factor in primary open angle glaucoma.","volume":"5","author":"Chen","year":"2012","journal-title":"Int. J. Ophthalmol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.exer.2018.12.011","article-title":"A derivative of betulinic acid protects human Retinal Pigment Epithelial (RPE) cells from cobalt chloride-induced acute hypoxic stress.","volume":"180","author":"Cheng","year":"2019","journal-title":"Exp. Eye Res."},{"key":"B26","doi-asserted-by":"crossref","first-page":"712","DOI":"10.4049\/jimmunol.153.2.712","article-title":"NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-like site.","volume":"153","author":"Cogswell","year":"1994","journal-title":"J. Immunol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/j.survophthal.2008.08.006","article-title":"Risk factors for glaucoma onset and progression.","volume":"53","author":"Coleman","year":"2008","journal-title":"Surv. Ophthalmol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1016\/s0161-5890(99)00116-9","article-title":"Complement activation following oxidative stress.","volume":"36","author":"Collard","year":"1999","journal-title":"Mol. Immunol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.jcjo.2016.07.013","article-title":"Glaucoma treatment trends: a review.","volume":"52","author":"Conlon","year":"2017","journal-title":"Can. J. Ophthalmol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1007\/s11626-016-0115-0","article-title":"Mesenchymal stem cells attenuate hydrogen peroxide-induced oxidative stress and enhance neuroprotective effects in retinal ganglion cells.","volume":"53","author":"Cui","year":"2017","journal-title":"In Vitro Cell. Dev. Biol. Anim."},{"key":"B31","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1002\/cne.902920402","article-title":"Human photoreceptor topography.","volume":"292","author":"Curcio","year":"1990","journal-title":"J. Comp. Neurol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.yexmp.2019.01.002","article-title":"Baicalin protects human retinal pigment epithelial cell lines against high glucose-induced cell injury by up-regulation of microRNA-145.","volume":"106","author":"Dai","year":"2019","journal-title":"Exp. Mol. Pathol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/j.exer.2005.06.004","article-title":"Mouse mutants as models for congenital retinal disorders.","volume":"81","author":"Dalke","year":"2005","journal-title":"Exp. Eye Res."},{"key":"B34","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.exer.2018.03.006","article-title":"Bilateral early activation of retinal microglial cells in a mouse model of unilateral laser-induced experimental ocular hypertension.","volume":"171","author":"de Hoz","year":"2018","journal-title":"Exp. Eye Res."},{"key":"B35","doi-asserted-by":"publisher","first-page":"5847","DOI":"10.1523\/JNEUROSCI.4401-10.2011","article-title":"Naturally occurring autoantibodies against beta-amyloid: investigating their role in transgenic animal and in vitro models of Alzheimer\u2019s disease.","volume":"31","author":"Dodel","year":"2011","journal-title":"J. Neurosci."},{"key":"B36","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1001\/archopht.1996.01100130295012","article-title":"Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma.","volume":"114","author":"Dreyer","year":"1996","journal-title":"Arch. Ophthalmol."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1610751","article-title":"Protection of kaempferol on oxidative stress-induced retinal pigment epithelial cell damage.","volume":"2018","author":"Du","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"key":"B38","doi-asserted-by":"publisher","first-page":"6448","DOI":"10.1167\/iovs.10-5284","article-title":"Microglial activation in the visual pathway in experimental glaucoma: spatiotemporal characterization and correlation with axonal injury.","volume":"51","author":"Ebneter","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1136\/bjophthalmol-2016-egsguideline.002","article-title":"European glaucoma society terminology and guidelines for glaucoma, 4th edition - chapter 2: classification and terminology.","volume":"101","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"317","DOI":"10.2119\/molmed.2010.00149","article-title":"New insights of an old defense system: structure, function, and clinical relevance of the complement system.","volume":"17","author":"Ehrnthaller","year":"2011","journal-title":"Mol. Med."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1093\/brain\/aws105","article-title":"Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis.","volume":"135","author":"Elliott","year":"2012","journal-title":"Brain"},{"key":"B42","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1007\/s10792-017-0795-9","article-title":"Pathophysiology of primary open-angle glaucoma from a neuroinflammatory and neurotoxicity perspective: a review of the literature.","volume":"39","author":"Evangelho","year":"2019","journal-title":"Int. Ophthalmol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"4381","DOI":"10.1167\/iovs.10-6987","article-title":"Incidence of blindness and severe visual impairment in Germany: projections for 2030.","volume":"52","author":"Finger","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B44","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1385\/ir:31:1:37","article-title":"The role of c5b-9 terminal complement complex in activation of the cell cycle and transcription.","volume":"31","author":"Fosbrink","year":"2005","journal-title":"Immunol. Res."},{"key":"B45","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1038\/nn.2511","article-title":"Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer\u2019s disease.","volume":"13","author":"Fuhrmann","year":"2010","journal-title":"Nat. Neurosci."},{"key":"B46","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1001\/archopht.119.8.1165","article-title":"Increased matrix metalloproteinases 1, 2, and 3 in the monkey uveoscleral outflow pathway after topical prostaglandin F(2 alpha)-isopropyl ester treatment.","volume":"119","author":"Gaton","year":"2001","journal-title":"Arch. Ophthalmol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s00401-009-0622-0","article-title":"Microglia: biology and pathology.","volume":"119","author":"Graeber","year":"2010","journal-title":"Acta Neuropathol."},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057557","article-title":"Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina.","volume":"8","author":"Gramlich","year":"2013","journal-title":"PLoS One"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-016-0542-6","article-title":"Immune response after intermittent minimally invasive intraocular pressure elevations in an experimental animal model of glaucoma.","volume":"13","author":"Gramlich","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"B50","doi-asserted-by":"publisher","first-page":"1000.e7","DOI":"10.1016\/j.amjmed.2016.03.038","article-title":"Emerging concepts in glaucoma and review of the literature.","volume":"129","author":"Greco","year":"2016","journal-title":"Am. J. Med."},{"key":"B51","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1034\/j.1600-0420.2002.800613.x","article-title":"A comparison of glaucoma patients identified through mass screening and in routine clinical practice.","volume":"80","author":"Grodum","year":"2002","journal-title":"Acta Ophthalmol. Scand."},{"key":"B52","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/bs.pmbts.2015.06.001","article-title":"Introduction to the retina.","volume":"134","author":"Grossniklaus","year":"2015","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"key":"B53","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1167\/iovs.05-0685","article-title":"Serum autoantibodies to alpha-fodrin are present in glaucoma patients from Germany and the United States.","volume":"47","author":"Grus","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B54","first-page":"132","article-title":"Complex autoantibody repertoires in patients with glaucoma.","volume":"10","author":"Grus","year":"2004","journal-title":"Mol. Vis."},{"key":"B55","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1097\/ijg.0b013e318156a592","article-title":"Autoimmunity and glaucoma.","volume":"17","author":"Grus","year":"2008","journal-title":"J. Glaucoma"},{"key":"B56","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.ijdevneu.2014.07.005","article-title":"Cerebrolysin protects PC12 cells from CoCl2-induced hypoxia employing GSK3beta signaling.","volume":"38","author":"Hartwig","year":"2014","journal-title":"Int. J. Dev. Neurosci."},{"key":"B57","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1006\/exer.2002.1181","article-title":"Distribution and density of medium- and short-wavelength selective cones in the domestic pig retina.","volume":"74","author":"Hendrickson","year":"2002","journal-title":"Exp. Eye Res."},{"key":"B58","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.preteyeres.2014.06.003","article-title":"Functional architecture of the retina: development and disease.","volume":"42","author":"Hoon","year":"2014","journal-title":"Prog. Retin. Eye Res."},{"key":"B59","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1172\/JCI44646","article-title":"Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma.","volume":"121","author":"Howell","year":"2011","journal-title":"J. Clin. Invest."},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-10-76","article-title":"Deficiency of complement component 5 ameliorates glaucoma in DBA\/2J mice.","volume":"10","author":"Howell","year":"2013","journal-title":"J. Neuroinflammation"},{"key":"B61","doi-asserted-by":"publisher","first-page":"6987","DOI":"10.1523\/JNEUROSCI.3955-14.2015","article-title":"Upregulation of P2RX7 in Cx3cr1-deficient mononuclear phagocytes leads to increased interleukin-1beta secretion and photoreceptor neurodegeneration.","volume":"35","author":"Hu","year":"2015","journal-title":"J. Neurosci."},{"key":"B62","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.ejpb.2017.06.009","article-title":"Ultrasound-mediated nanoparticle delivery across ex vivo bovine retina after intravitreal injection.","volume":"119","author":"Huang","year":"2017","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"B63","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1177\/026119291704500105","article-title":"A novel porcine ex vivo retina culture model for oxidative stress induced by H(2)O(2).","volume":"45","author":"Hurst","year":"2017","journal-title":"Altern. Lab. Anim."},{"key":"B64","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1038\/353655a0","article-title":"Retinal receptors in rodents maximally sensitive to ultraviolet light.","volume":"353","author":"Jacobs","year":"1991","journal-title":"Nature"},{"key":"B65","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1016\/j.molimm.2011.07.012","article-title":"Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma.","volume":"48","author":"Jha","year":"2011","journal-title":"Mol. Immunol."},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143952","article-title":"Spatiotemporal cadence of macrophage polarisation in a model of light-induced retinal degeneration.","volume":"10","author":"Jiao","year":"2015","journal-title":"PLoS One"},{"key":"B67","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1080\/02713680701375183","article-title":"Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor.","volume":"32","author":"Joachim","year":"2007","journal-title":"Curr. Eye Res."},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040616","article-title":"Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens.","volume":"7","author":"Joachim","year":"2012","journal-title":"PLoS One"},{"key":"B69","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1007\/s12031-013-0125-2","article-title":"Apoptotic retinal ganglion cell death in an autoimmune glaucoma model is accompanied by antibody depositions.","volume":"52","author":"Joachim","year":"2014","journal-title":"J. Mol. Neurosci."},{"key":"B70","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1007\/s00417-004-1094-5","article-title":"Autoantibodies in patients with glaucoma: a comparison of IgG serum antibodies against retinal, optic nerve, and optic nerve head antigens.","volume":"243","author":"Joachim","year":"2005","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1007\/s00417-007-0737-8","article-title":"Sera of glaucoma patients show autoantibodies against myelin basic protein and complex autoantibody profiles against human optic nerve antigens.","volume":"246","author":"Joachim","year":"2008","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.preteyeres.2014.11.004","article-title":"Retinal microglia: just bystander or target for therapy?","volume":"45","author":"Karlstetter","year":"2015","journal-title":"Prog. Retin. Eye Res."},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2015.73","article-title":"Macrophage- and RIP3-dependent inflammasome activation exacerbates retinal detachment-induced photoreceptor cell death.","volume":"6","author":"Kataoka","year":"2015","journal-title":"Cell Death Dis."},{"key":"B74","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1073\/pnas.10.7.329","article-title":"The inheritance of a retinal abnormality in white mice.","volume":"10","author":"Keeler","year":"1924","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B75","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.preteyeres.2008.07.001","article-title":"The dynamics of leukocyte infiltration in experimental autoimmune uveoretinitis.","volume":"27","author":"Kerr","year":"2008","journal-title":"Prog. Retin. Eye Res."},{"key":"B76","first-page":"741","article-title":"Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons.","volume":"41","author":"Kerrigan-Baumrind","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B77","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1152\/physrev.00011.2010","article-title":"Physiology of microglia.","volume":"91","author":"Kettenmann","year":"2011","journal-title":"Physiol. Rev."},{"key":"B78","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.bbr.2008.09.040","article-title":"Minocycline and neurodegenerative diseases.","volume":"196","author":"Kim","year":"2009","journal-title":"Behav. Brain Res."},{"key":"B79","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/s0304-3940(01)01830-4","article-title":"Patterns of retinal ganglion cell survival after brain-derived neurotrophic factor administration in hypertensive eyes of rats.","volume":"305","author":"Ko","year":"2001","journal-title":"Neurosci. Lett."},{"key":"B80","first-page":"357","article-title":"Microglia, the first line of defence in brain pathologies.","volume":"45","author":"Kreutzberg","year":"1995","journal-title":"Arzneimittelforschung"},{"key":"B81","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s0169-328x(00)00224-2","article-title":"Characterization of a transformed rat retinal ganglion cell line.","volume":"86","author":"Krishnamoorthy","year":"2001","journal-title":"Brain Res. Mol. Brain Res."},{"key":"B82","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1038\/nrneurol.2012.203","article-title":"B cells and antibodies in multiple sclerosis pathogenesis and therapy.","volume":"8","author":"Krumbholz","year":"2012","journal-title":"Nat. Rev. Neurol."},{"key":"B83","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.exer.2006.03.002","article-title":"Retinal synthesis and deposition of complement components induced by ocular hypertension.","volume":"83","author":"Kuehn","year":"2006","journal-title":"Exp. Eye Res."},{"key":"B84","article-title":"Important role of microglia in a novel S100B based retina degeneration model.","volume":"59","author":"Kuehn","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B85","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.exer.2017.01.003","article-title":"Degenerative effects of cobalt-chloride treatment on neurons and microglia in a porcine retina organ culture model.","volume":"155","author":"Kuehn","year":"","journal-title":"Exp. Eye Res."},{"key":"B86","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/s12031-017-0978-x","article-title":"Concentration-dependent inner retina layer damage and optic nerve degeneration in a NMDA model.","volume":"63","author":"Kuehn","year":"","journal-title":"J. Mol. Neurosci."},{"key":"B87","author":"Lang","year":"2014","journal-title":"Augenheilkunde."},{"key":"B88","doi-asserted-by":"publisher","first-page":"8835","DOI":"10.1167\/iovs.10-6889","article-title":"Autoreactive antibodies and loss of retinal ganglion cells in rats induced by immunization with ocular antigens.","volume":"52","author":"Laspas","year":"2011","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B89","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/S0161-6420(98)91129-0","article-title":"Q-switched 532-nm Nd:YAG laser trabeculoplasty (selective laser trabeculoplasty): a multicenter, pilot, clinical study.","volume":"105","author":"Latina","year":"1998","journal-title":"Ophthalmology"},{"key":"B90","doi-asserted-by":"publisher","first-page":"2416","DOI":"10.1016\/j.ajpath.2011.01.013","article-title":"Interleukin-1beta inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration.","volume":"178","author":"Lavalette","year":"2011","journal-title":"Am. J. Pathol."},{"key":"B91","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1001\/archopht.124.4.520","article-title":"Minocycline delays death of retinal ganglion cells in experimental glaucoma and after optic nerve transection.","volume":"124","author":"Levkovitch-Verbin","year":"2006","journal-title":"Arch. Ophthalmol."},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084171","article-title":"Ginsenoside Rg-1 protects retinal pigment epithelium (RPE) cells from cobalt chloride (CoCl2) and hypoxia assaults.","volume":"8","author":"Li","year":"2013","journal-title":"PLoS One"},{"key":"B93","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s10633-019-09676-9","article-title":"Fisetin rescues retinal functions by suppressing inflammatory response in a DBA\/2J mouse model of glaucoma.","volume":"138","author":"Li","year":"2019","journal-title":"Doc. Ophthalmol."},{"key":"B94","doi-asserted-by":"publisher","first-page":"25","DOI":"10.3892\/br.2014.370","article-title":"A novel method for co-culture with Muller cells and microglia in rat retina in vitro.","volume":"3","author":"Li","year":"2015","journal-title":"Biomed. Rep."},{"key":"B95","first-page":"808","article-title":"Rhodopsin transgenic pigs as a model for human retinitis pigmentosa.","volume":"39","author":"Li","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B96","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1002\/art.37801","article-title":"Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls.","volume":"65","author":"Liao","year":"2013","journal-title":"Arthritis Rheum."},{"key":"B97","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.gene.2016.01.001","article-title":"Identification and validation of reference genes for quantitative RT-PCR analysis of retinal pigment epithelium cells under hypoxia and\/or hyperglycemia.","volume":"580","author":"Liu","year":"2016","journal-title":"Gene"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41113-4","article-title":"Diminished apoptosis in hypoxic porcine retina explant cultures through hypothermia.","volume":"9","author":"Maliha","year":"2019","journal-title":"Sci. Rep."},{"key":"B99","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1167\/iovs.02-1332","article-title":"Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.","volume":"44","author":"Martin","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B100","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1016\/j.ajo.2004.12.056","article-title":"Predictive factors for progressive optic nerve damage in various types of chronic open-angle glaucoma.","volume":"139","author":"Martus","year":"2005","journal-title":"Am. J. Ophthalmol."},{"key":"B101","first-page":"1657","article-title":"Retinal ganglion cells recognized by serum autoantibody against gamma-enolase found in glaucoma patients.","volume":"41","author":"Maruyama","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B102","doi-asserted-by":"publisher","first-page":"2637","DOI":"10.4049\/jimmunol.165.5.2637","article-title":"Proteolytic activities of two types of mannose-binding lectin-associated serine protease.","volume":"165","author":"Matsushita","year":"2000","journal-title":"J. Immunol."},{"key":"B103","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.optom.2016.02.003","article-title":"Glaucoma history and risk factors.","volume":"10","author":"McMonnies","year":"2017","journal-title":"J. Optom."},{"key":"B104","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1016\/s0161-6420(96)30449-1","article-title":"Prevalence of open-angle glaucoma in Australia. The blue mountains eye study.","volume":"103","author":"Mitchell","year":"1996","journal-title":"Ophthalmology"},{"key":"B105","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1080\/03009734.2018.1431744","article-title":"A model to study complement involvement in experimental retinal degeneration.","volume":"123","author":"Mohlin","year":"2018","journal-title":"Ups. J. Med. Sci."},{"key":"B106","author":"Murphy","year":"2008","journal-title":"Janeway\u2019s Immunobiology."},{"key":"B107","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4103\/0301-4738.30707","article-title":"A randomized, crossover, open label pilot study to evaluate the efficacy and safety of Xalatan in comparison with generic Latanoprost (Latoprost) in subjects with primary open angle glaucoma or ocular hypertension.","volume":"55","author":"Narayanaswamy","year":"2007","journal-title":"Indian J. Ophthalmol."},{"key":"B108","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1126\/science.2937147","article-title":"Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.","volume":"232","author":"Nathans","year":"1986","journal-title":"Science"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-017-0175-y","article-title":"Microglia-derived IL-1beta promotes chemokine expression by Muller cells and RPE in focal retinal degeneration.","volume":"12","author":"Natoli","year":"2017","journal-title":"Mol. Neurodegener."},{"key":"B110","doi-asserted-by":"publisher","first-page":"2853","DOI":"10.1002\/eji.200323888","article-title":"Mannose-binding lectin engagement with late apoptotic and necrotic cells.","volume":"33","author":"Nauta","year":"2003","journal-title":"Eur. J. Immunol."},{"key":"B111","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1556\/EuJMI.2.2012.2.2","article-title":"The complement system: history, pathways, cascade and inhibitors.","volume":"2","author":"Nesargikar","year":"2012","journal-title":"Eur. J. Microbiol. Immunol."},{"key":"B112","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1001\/archopht.1997.01100150499009","article-title":"Nitric oxide synthase in the human glaucomatous optic nerve head.","volume":"115","author":"Neufeld","year":"1997","journal-title":"Arch. Ophthalmol."},{"key":"B113","doi-asserted-by":"publisher","first-page":"6091","DOI":"10.1167\/iovs.17-22634","article-title":"AAV2-mediated transduction of the mouse retina after optic nerve injury.","volume":"58","author":"Nickells","year":"2017","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B114","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1007\/s12031-015-0707-2","article-title":"Retinal and optic nerve damage is associated with early glial responses in an experimental autoimmune glaucoma model.","volume":"58","author":"Noristani","year":"2016","journal-title":"J. Mol. Neurosci."},{"key":"B115","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/j.neuro.2005.06.002","article-title":"Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat.","volume":"26","author":"Nucci","year":"2005","journal-title":"Neurotoxicology"},{"key":"B116","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1084\/jem.194.6.781","article-title":"C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells.","volume":"194","author":"Ogden","year":"2001","journal-title":"J. Exp. Med."},{"key":"B117","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1002\/ana.20338","article-title":"Microglial activation and dopamine terminal loss in early Parkinson\u2019s disease.","volume":"57","author":"Ouchi","year":"2005","journal-title":"Ann. Neurol."},{"key":"B118","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.phrs.2012.03.002","article-title":"Protecting the retinal neurons from glaucoma: lowering ocular pressure is not enough.","volume":"66","author":"Pascale","year":"2012","journal-title":"Pharmacol. Res."},{"key":"B119","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1080\/10717544.2017.1375578","article-title":"Toward smart design of retinal drug carriers: a novel bovine retinal explant model to study the barrier role of the vitreoretinal interface.","volume":"24","author":"Peynshaert","year":"2017","journal-title":"Drug Deliv."},{"key":"B120","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1056\/NEJM199304153281507","article-title":"Open-angle glaucoma.","volume":"328","author":"Quigley","year":"1993","journal-title":"N. Engl. J. Med."},{"key":"B121","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020.","volume":"90","author":"Quigley","year":"2006","journal-title":"Br. J. Ophthalmol."},{"key":"B122","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1097\/00061198-200312000-00001","article-title":"How are glaucoma patients identified?","volume":"12","author":"Quigley","year":"2003","journal-title":"J. Glaucoma"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2017.00214","article-title":"The role of microglia in retinal neurodegeneration: Alzheimer\u2019s disease, Parkinson, and glaucoma.","volume":"9","author":"Ramirez","year":"2017","journal-title":"Front. Aging Neurosci."},{"key":"B124","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1167\/iovs.02-0199","article-title":"Pathogenic role of retinal microglia in experimental uveoretinitis.","volume":"44","author":"Rao","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B125","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/s00441-017-2710-0","article-title":"HSP27 immunization reinforces AII amacrine cell and synapse damage induced by S100 in an autoimmune glaucoma model.","volume":"371","author":"Reinehr","year":"","journal-title":"Cell Tissue Res."},{"key":"B126","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-28183-6","article-title":"S100B immunization triggers NF\u03baB and complement activation in an autoimmune glaucoma model.","volume":"8","author":"Reinehr","year":"","journal-title":"Sci. Rep."},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2016.00140","article-title":"Simultaneous complement response via lectin pathway in retina and optic nerve in an experimental autoimmune glaucoma model.","volume":"10","author":"Reinehr","year":"","journal-title":"Front. Cell. Neurosci."},{"key":"B128","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1111\/jcmm.12909","article-title":"Early remodelling of the extracellular matrix proteins tenascin-C and phosphacan in retina and optic nerve of an experimental autoimmune glaucoma model.","volume":"20","author":"Reinehr","year":"","journal-title":"J. Cell. Mol. Med."},{"key":"B129","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-11-133","article-title":"Microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers.","volume":"11","author":"Rojas","year":"2014","journal-title":"J. Neuroinflammation"},{"key":"B130","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.ejphar.2016.03.064","article-title":"Retinal ganglion cell death in glaucoma: exploring the role of neuroinflammation.","volume":"787","author":"Russo","year":"2016","journal-title":"Eur. J. Pharmacol."},{"key":"B131","first-page":"844","article-title":"Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas\/FasL-caspase-3.","volume":"23","author":"Sanchez-Bretano","year":"2017","journal-title":"Mol. Vis."},{"key":"B132","doi-asserted-by":"publisher","first-page":"2777","DOI":"10.1167\/iovs.13-13372","article-title":"Loss of inner retinal neurons after retinal ischemia in rats.","volume":"55","author":"Schmid","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B133","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/978-1-4614-3209-8_19","article-title":"What is the nature of the RGC-5 cell line?","volume":"801","author":"Sippl","year":"2014","journal-title":"Adv. Exp. Med. Biol."},{"key":"B134","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1001\/archopht.1991.01080080050026","article-title":"Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans. The Baltimore eye survey.","volume":"109","author":"Sommer","year":"1991","journal-title":"Arch. Ophthalmol."},{"key":"B135","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.2147\/DDDT.S80594","article-title":"Neuroprotective therapies for glaucoma.","volume":"9","author":"Song","year":"2015","journal-title":"Drug Des. Devel. Ther."},{"key":"B136","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1111\/j.0022-202x.2005.23673.x","article-title":"C1q: its functions within the innate and adaptive immune responses and its role in lupus autoimmunity.","volume":"125","author":"Sontheimer","year":"2005","journal-title":"J. Invest. Dermatol."},{"key":"B137","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1167\/iovs.05-0830","article-title":"Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes.","volume":"47","author":"Stasi","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B138","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1016\/j.ophtha.2013.05.025","article-title":"Global prevalence of vision impairment and blindness: magnitude and temporal trends, 1990-2010.","volume":"120","author":"Stevens","year":"2013","journal-title":"Ophthalmology"},{"key":"B139","doi-asserted-by":"publisher","first-page":"3220","DOI":"10.4049\/jimmunol.174.6.3220","article-title":"Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype.","volume":"174","author":"Stuart","year":"2005","journal-title":"J. Immunol."},{"key":"B140","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1002\/cne.902730413","article-title":"Identification of the blue-sensitive cones in the mammalian retina by anti-visual pigment antibody.","volume":"273","author":"Szel","year":"1988","journal-title":"J. Comp. Neurol."},{"key":"B141","doi-asserted-by":"publisher","first-page":"6132","DOI":"10.4049\/jimmunol.180.9.6132","article-title":"Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway.","volume":"180","author":"Takahashi","year":"2008","journal-title":"J. Immunol."},{"key":"B142","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.exer.2010.07.009","article-title":"The immune response in glaucoma: a perspective on the roles of oxidative stress.","volume":"93","author":"Tezel","year":"2011","journal-title":"Exp. Eye Res."},{"key":"B143","first-page":"2277","article-title":"Autoantibodies to small heat shock proteins in glaucoma.","volume":"39","author":"Tezel","year":"1998","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B144","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1097\/00055735-200404000-00003","article-title":"The immune system and glaucoma.","volume":"15","author":"Tezel","year":"2004","journal-title":"Curr. Opin. Ophthalmol."},{"key":"B145","doi-asserted-by":"publisher","first-page":"5071","DOI":"10.1167\/iovs.10-5289","article-title":"Oxidative stress and the regulation of complement activation in human glaucoma.","volume":"51","author":"Tezel","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B146","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1001\/jama.266.3.369","article-title":"Racial variations in the prevalence of primary open-angle glaucoma. The Baltimore eye survey.","volume":"266","author":"Tielsch","year":"1991","journal-title":"JAMA"},{"key":"B147","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1167\/iovs.08-2767","article-title":"Analysis of postnatal eye development in the mouse with high-resolution small animal magnetic resonance imaging.","volume":"51","author":"Tkatchenko","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B148","article-title":"Medical interventions for primary open angle glaucoma and ocular hypertension.","volume":"4","author":"Vass","year":"2007","journal-title":"Cochrane Database Syst. Rev."},{"key":"B149","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125631","article-title":"A comparison of some organizational characteristics of the mouse central retina and the human macula.","volume":"10","author":"Volland","year":"2015","journal-title":"PLoS One"},{"key":"B150","first-page":"1088","article-title":"Immunohistologic evidence for retinal glial cell changes in human glaucoma.","volume":"43","author":"Wang","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B151","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.exer.2010.08.016","article-title":"The case for autoimmunity in glaucoma.","volume":"93","author":"Wax","year":"2011","journal-title":"Exp. Eye Res."},{"key":"B152","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/s0002-9394(14)70059-5","article-title":"Increased incidence of paraproteinemia and autoantibodies in patients with normal-pressure glaucoma.","volume":"117","author":"Wax","year":"1994","journal-title":"Am. J. Ophthalmol."},{"key":"B153","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1001\/archopht.116.8.993","article-title":"Clinical and ocular histopathological findings in a patient with normal-pressure glaucoma.","volume":"116","author":"Wax","year":"1998","journal-title":"Arch. Ophthalmol."},{"key":"B154","doi-asserted-by":"publisher","first-page":"12085","DOI":"10.1523\/JNEUROSCI.3200-08.2008","article-title":"Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand.","volume":"28","author":"Wax","year":"2008","journal-title":"J. Neurosci."},{"key":"B155","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-016-0091-6","article-title":"Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma.","volume":"11","author":"Williams","year":"2016","journal-title":"Mol. Neurodegener."},{"key":"B156","doi-asserted-by":"publisher","first-page":"3774","DOI":"10.1167\/iovs.09-4305","article-title":"A comparison of differentiation protocols for RGC-5 cells.","volume":"51","author":"Wood","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"B157","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.gene.2017.03.027","article-title":"Transcription factor SP1 mediates hyperglycemia-induced upregulation of roundabout4 in retinal microvascular endothelial cells.","volume":"616","author":"Xie","year":"2017","journal-title":"Gene"},{"key":"B158","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1006\/exer.2001.1072","article-title":"Interleukin-1beta mediates ischemic injury in the rat retina.","volume":"73","author":"Yoneda","year":"2001","journal-title":"Exp. Eye Res."},{"key":"B159","doi-asserted-by":"publisher","first-page":"53","DOI":"10.4196\/kjpp.2016.20.1.53","article-title":"Effects of CoCl2 on multi-lineage differentiation of C3H\/10T1\/2 mesenchymal stem cells.","volume":"20","author":"Yoo","year":"2016","journal-title":"Korean J. Physiol. Pharmacol."},{"key":"B160","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.cbi.2019.01.018","article-title":"SIRT6 protects retinal ganglion cells against hydrogen peroxide-induced apoptosis and oxidative stress by promoting Nrf2\/ARE signaling via inhibition of Bach1.","volume":"300","author":"Yu","year":"2019","journal-title":"Chem. Biol. Interact."},{"key":"B161","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1002\/jnr.1104","article-title":"Activated microglia in the human glaucomatous optic nerve head.","volume":"64","author":"Yuan","year":"2001","journal-title":"J. Neurosci. Res."},{"key":"B162","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1097\/IJG.0b013e31815c3a7f","article-title":"Oxidative stress in primary open-angle glaucoma.","volume":"17","author":"Zanon-Moreno","year":"2008","journal-title":"J. Glaucoma"},{"key":"B163","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1001\/archophthalmol.2007.65","article-title":"Microglial activation in human diabetic retinopathy.","volume":"126","author":"Zeng","year":"2008","journal-title":"Arch. Ophthalmol."},{"key":"B164","first-page":"61","article-title":"Target pressures in glaucoma.","volume":"274","author":"Zeyen","year":"1999","journal-title":"Bull. Soc. Belge Ophtalmol."},{"key":"B165","doi-asserted-by":"publisher","first-page":"936","DOI":"10.3892\/ijmm.2018.4027","article-title":"Genipin protects against H2O2-induced oxidative damage in retinal pigment epithelial cells by promoting Nrf2 signaling.","volume":"43","author":"Zhao","year":"2019","journal-title":"Int. J. Mol. Med."},{"key":"B166","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.15252\/emmm.201505298","article-title":"Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration.","volume":"7","author":"Zhao","year":"2015","journal-title":"EMBO Mol. Med."},{"key":"B167","first-page":"2214","article-title":"A comparative gene expression profile of the whole eye from human, mouse, and guinea pig.","volume":"13","author":"Zhou","year":"2007","journal-title":"Mol. Vis."}],"container-title":["Frontiers in Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnins.2019.00931\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T19:09:36Z","timestamp":1695150576000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnins.2019.00931\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,2]]},"references-count":167,"alternative-id":["10.3389\/fnins.2019.00931"],"URL":"https:\/\/doi.org\/10.3389\/fnins.2019.00931","relation":{},"ISSN":["1662-453X"],"issn-type":[{"value":"1662-453X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,2]]},"article-number":"931"}}