{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T17:01:55Z","timestamp":1774976515407,"version":"3.50.1"},"reference-count":46,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T00:00:00Z","timestamp":1607558400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:p>Obstructive sleep apnea hypopnea syndrome (OSAHS) and parasomnia overlap disorder (POD) are types of sleep disorders. When the symptoms of both conditions coexist, the POD symptoms are most likely caused by OSAHS. In these cases, the symptoms of POD will be relieved when OSAHS is effectively treated. We refer to these cases as symptomatic POD (related to OSAHS), which differs in pathophysiology, complications, and treatment from idiopathic POD. It is important to note that the treatment for idiopathic POD may aggravate the symptoms of OSAHS. In this case, we used video polysomnography (v-PSG) on a POD patient with suspected OSAHS to distinguish idiopathic POD from symptomatic POD, to inform the appropriate treatment course. The video results and clinical features lead us to diagnose symptomatic POD, and we treated the patient with auto-set continuous positive airway pressure to address their OSAHS. This course of treatment resolved all POD-related symptoms. Here, we discuss this case and review the relevant literature. This report highlights the importance of the use of v-PSG in the clinical diagnosis, differential diagnosis, and subsequent treatment of POD.<\/jats:p>","DOI":"10.3389\/fnins.2020.578171","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T07:41:59Z","timestamp":1607586119000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Parasomnia Overlap Disorder Induced by Obstructive Sleep Hypopnea Apnea Syndrome: A Case Report and Literature Review"],"prefix":"10.3389","volume":"14","author":[{"given":"Yun","family":"Sun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinjun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingyan","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shutong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijie","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,12,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.01127","article-title":"Dreams and Nightmares in Patients With Obstructive Sleep Apnea: A Review.","volume":"10","author":"BaHammam","year":"2019","journal-title":"Front. Neurol."},{"key":"B2","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.sleep.2010.07.011","article-title":"Prevalence of different parasomnias in the general population.","volume":"11","author":"Bjorvatn","year":"2010","journal-title":"Sleep Med."},{"key":"B3","doi-asserted-by":"crossref","first-page":"108","DOI":"10.5664\/jcsm.1676","article-title":"Differentiating parasomnias from nocturnal seizures.","volume":"8","author":"Boursoulian","year":"2012","journal-title":"J. Clin. Sleep Med."},{"key":"B4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.sleep.2017.08.014","article-title":"Sleep apneas trigger epilepsy.","volume":"39","author":"Brunetti","year":"2017","journal-title":"Sleep Med."},{"key":"B5","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.sleep.2017.05.012","article-title":"The influence of sleep disordered breathing in REM sleep behavior disorder.","volume":"37","author":"Bugalho","year":"2017","journal-title":"Sleep Med."},{"key":"B6","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1111\/j.1365-2869.2006.00553.x","article-title":"Changes in dreaming induced by CPAP in severe obstructive sleep apnea syndrome patients.","volume":"15","author":"Carrasco","year":"2006","journal-title":"J. Sleep Res."},{"key":"B7","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/s41582-018-0030-y","article-title":"NREM sleep parasomnias as disorders of sleep-state dissociation.","volume":"14","author":"Castelnovo","year":"2018","journal-title":"Nat. Rev. Neurol."},{"key":"B8","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.sleep.2013.06.012","article-title":"Parasomnia overlap disorder: a distinct pathophysiologic entity or a variant of rapid eye movement sleep behavior disorder? A case series.","volume":"14","author":"Dumitrascu","year":"2013","journal-title":"Sleep Med."},{"key":"B9","article-title":"NREM and other parasomnias","author":"Ferri","year":"2017","journal-title":"Oxford Textbook of Sleep Disorders"},{"key":"B10","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s11325-017-1563-9","article-title":"Prevalence of obstructive sleep apnoea in REM behaviour disorder: response to continuous positive airway pressure therapy.","volume":"22","author":"Gabryelska","year":"2018","journal-title":"Sleep Breath."},{"key":"B11","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1001\/jama.2020.3514","article-title":"Diagnosis and Management of Obstructive Sleep Apnea: A Review.","volume":"323","author":"Gottlieb","year":"2020","journal-title":"JAMA"},{"key":"B12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s41782-017-0029-2","article-title":"A case of pseudo-RBD with OSA.","volume":"2","author":"Goyal","year":"2018","journal-title":"Sleep Vigilance"},{"key":"B13","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1542\/peds.111.1.e17","article-title":"Sleepwalking and sleep terrors in prepubertal children: what triggers them?","volume":"111","author":"Guilleminault","year":"2003","journal-title":"Pediatrics"},{"key":"B14","doi-asserted-by":"crossref","first-page":"165","DOI":"10.5664\/jcsm.4466","article-title":"Obstructive sleep apnea and psychiatric disorders: a systematic review.","volume":"11","author":"Gupta","year":"2015","journal-title":"J. Clin. Sleep Med."},{"key":"B15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2869.2004.00388.x","article-title":"The nature of arousal in sleep.","volume":"13","author":"Halasz","year":"2004","journal-title":"J. Sleep Res."},{"key":"B16","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3928\/00904481-20130924-12","article-title":"Just a scary dream? A brief review of sleep terrors, nightmares, and rapid eye movement sleep behavior disorder.","volume":"42","author":"Haupt","year":"2013","journal-title":"Pediatr. Ann."},{"key":"B17","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1378\/chest.14-1949","article-title":"The effect of OSA on work disability and work-related injuries.","volume":"147","author":"Hirsch Allen","year":"2015","journal-title":"Chest"},{"key":"B18","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s13311-012-0143-8","article-title":"Parasomnias: an updated review.","volume":"9","author":"Howell","year":"2012","journal-title":"Neurotherapeutics"},{"key":"B19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3390\/clockssleep1010009","article-title":"Adult NREM Parasomnias: An Update.","volume":"1","author":"Hrozanova","year":"2019","journal-title":"Clocks Sleep"},{"key":"B20","doi-asserted-by":"crossref","first-page":"909","DOI":"10.5665\/SLEEP.1126","article-title":"Amelioration of obstructive sleep apnea in REM sleep behavior disorder: implications for the neuromuscular control of OSA.","volume":"34","author":"Huang","year":"2011","journal-title":"Sleep"},{"key":"B21","first-page":"1035","article-title":"Non-Rapid Eye Movement Sleep and Overlap Parasomnias.","volume":"23","author":"Irfan","year":"2017","journal-title":"Continuum"},{"key":"B22","article-title":"Obesity, obstructive sleep apnea and type 2 diabetes mellitus: Epidemiology and pathophysiologic insights.","volume":"2","author":"Jehan","year":"2018","journal-title":"Sleep Med. Disord. Int. J."},{"key":"B23","doi-asserted-by":"crossref","first-page":"479","DOI":"10.5664\/jcsm.6506","article-title":"Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline.","volume":"13","author":"Kapur","year":"2017","journal-title":"J. Clin. Sleep Med."},{"key":"B24","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx012","article-title":"Association of mild obstructive sleep apnea with cognitive performance, excessive daytime sleepiness, and quality of life in the general population: the Korean Genome and Epidemiology Study (KoGES).","volume":"40","author":"Kim","year":"2017","journal-title":"Sleep"},{"key":"B25","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/8713409","article-title":"Cyclic Alternating Pattern in Obstructive Sleep Apnea Patients with versus without Excessive Sleepiness.","volume":"2018","author":"Korkmaz","year":"2018","journal-title":"Sleep Disord."},{"key":"B26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/978-1-4614-7627-6_2","article-title":"Pathophysiology of parasomnias","author":"Kotagal","year":"2013","journal-title":"Parasomnias"},{"key":"B27","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00702-015-1501-6","article-title":"Cognitive deficits in adults with obstructive sleep apnea compared to children and adolescents.","volume":"124","author":"Krysta","year":"2017","journal-title":"J. Neural Trans."},{"key":"B28","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.sleep.2016.04.017","article-title":"Video-polysomnographic documentation of non-rapid eye movement sleep parasomnia followed by rapid eye movement sleep behavior disorder: a parasomnia overlap disorder?","volume":"23","author":"Matos","year":"2016","journal-title":"Sleep Med."},{"key":"B29","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsz142","article-title":"Isolated rapid eye movement sleep behavior disorder and cyclic alternating pattern: is sleep microstructure a predictive parameter of neurodegeneration?","volume":"42","author":"Melpignano","year":"2019","journal-title":"Sleep"},{"key":"B30","doi-asserted-by":"crossref","DOI":"10.1088\/1361-6579\/ab4f08","article-title":"Sleep quality of subjects with and without sleep-disordered breathing based on the cyclic alternating pattern rate estimation from single-lead ECG.","volume":"40","author":"Mendonca","year":"2019","journal-title":"Physiol. Meas."},{"key":"B31","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.smrv.2011.02.003","article-title":"Cyclic alternating pattern (CAP): the marker of sleep instability.","volume":"16","author":"Parrino","year":"2012","journal-title":"Sleep Med. Rev."},{"key":"B32","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/MCP.0000000000000100","article-title":"Cyclic alternating pattern in polysomnography: what is it and what does it mean?","volume":"20","author":"Parrino","year":"2014","journal-title":"Curr. Opin. Pulm. Med."},{"key":"B33","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/mds.26347","article-title":"REM sleep behavior disorder and neuropathology in Parkinson\u2019s disease.","volume":"30","author":"Postuma","year":"2015","journal-title":"Mov. Disord."},{"key":"B34","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.sleep.2017.05.014","article-title":"Overlap Parasomnia Disorder in a case of Creutzfeldt-Jakob Disease.","volume":"36","author":"Puligheddu","year":"2017","journal-title":"Sleep Med."},{"key":"B35","doi-asserted-by":"crossref","DOI":"10.1007\/s11886-020-1257-y","article-title":"Obstructive sleep apnea, hypertension, and cardiovascular risk: epidemiology, pathophysiology, and management.","volume":"22","author":"Salman","year":"2020","journal-title":"Curr. Cardiol. Rep."},{"key":"B36","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1479-8425.2012.00548.x","article-title":"Spectrum of rapid eye movement sleep behavior disorder (overlap between rapid eye movement sleep behavior disorder and other parasomnias).","volume":"11","author":"Schenck","year":"2013","journal-title":"Sleep Biol. Rhythms"},{"key":"B37","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/978-3-319-90152-7_27","article-title":"Parasomnia overlap disorder: RBD and NREM parasomnias","author":"Schenck","year":"2019","journal-title":"Rapid-Eye-Movement Sleep Behavior Disorder"},{"key":"B38","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0733-8619(05)70281-4","article-title":"REM sleep parasomnias.","volume":"14","author":"Schenck","year":"1996","journal-title":"Neurol. Clin."},{"key":"B39","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.ncl.2005.06.002","article-title":"Rapid eye movement sleep parasomnias.","volume":"23","author":"Schenck","year":"2005","journal-title":"Neurol. Clin."},{"key":"B40","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s11818-008-0332-1","article-title":"Parasomnias associated with sleep-disordered breathing and its therapy, including sexsomnia as a recently recognized parasomnia.","volume":"12","author":"Schenck","year":"2008","journal-title":"Somnol. Schlafforschung und Schlafmedizin"},{"key":"B41","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1093\/sleep\/20.11.972","article-title":"A parasomnia overlap disorder involving sleepwalking, sleep terrors, and REM sleep behavior disorder in 33 polysomnographically confirmed cases.","volume":"20","author":"Schenck","year":"1997","journal-title":"Sleep"},{"key":"B42","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.5664\/jcsm.6066","article-title":"Parasomnia Overlap Disorder with Sexual Behaviors during Sleep in a Patient with Obstructive Sleep Apnea.","volume":"12","author":"Soca","year":"2016","journal-title":"J. Clin. Sleep Med."},{"key":"B43","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1093\/sleep\/30.5.553","article-title":"Cyclic alternating pattern in the electroencephalogram: what is its clinical utility?","volume":"30","author":"Thomas","year":"2007","journal-title":"Sleep"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01513","article-title":"Benzodiazepines Associated With Acute Respiratory Failure in Patients With Obstructive Sleep Apnea.","volume":"9","author":"Wang","year":"2018","journal-title":"Front. Pharmacol."},{"key":"B45","first-page":"561","article-title":"Clinical consequences and economic costs of obstructive sleep apnea syndrome.","volume":"42","author":"Xiao","year":"2019","journal-title":"Zhonghua Jie He He Hu Xi Za Zhi."},{"key":"B46","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.sleep.2019.01.041","article-title":"Parasomnia overlap disorder with adolescent-onset presumed REM sleep behavior disorder converting to Parkinson\u2019s disease after 48 years.","volume":"57","author":"Xu","year":"2019","journal-title":"Sleep Med."}],"container-title":["Frontiers in Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnins.2020.578171\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T07:42:08Z","timestamp":1607586128000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnins.2020.578171\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,10]]},"references-count":46,"alternative-id":["10.3389\/fnins.2020.578171"],"URL":"https:\/\/doi.org\/10.3389\/fnins.2020.578171","relation":{},"ISSN":["1662-453X"],"issn-type":[{"value":"1662-453X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,10]]},"article-number":"578171"}}