{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T23:01:12Z","timestamp":1767999672252,"version":"3.49.0"},"reference-count":131,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T00:00:00Z","timestamp":1668643200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009377","name":"Education Department of Hunan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009377","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009377","name":"Education Department of Hunan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009377","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Scholars have long understood that gastrointestinal microorganisms are intimately related to human disorders. The literature on research involving the gut microbiome and neuroscience is emerging. This study exposed the connections between gut microbiota and neuroscience methodically and intuitively using bibliometrics and visualization. This study\u2019s objectives were to summarize the knowledge structure and identify emerging trends and potential hotspots in this field.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>On October 18, 2022, a literature search was conducted utilizing the Web of Science Core Collection (WoSCC) database for studies on gut microbiota and neuroscience studies from 2002 to 2022 (August 20, 2022). VOSviewer and CiteSpace V software was used to conduct the bibliometrics and visualization analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2002 to 2022 (August 20, 2022), 2,275 publications in the WoSCC database satisfied the criteria. The annual volume of publications has rapidly emerged in recent years (2016\u20132022). The most productive nation (<jats:italic>n<\/jats:italic> = 732, 32.18%) and the hub of inter-country cooperation (links: 38) were the United States. University College Cork had the most research papers published in this area, followed by McMaster University and Harvard Medical School. Cryan JF, Dinan TG, and Clarke G were key researchers with considerable academic influence. The journals with the most publications are \u201cNeurogastroenterology and Motility\u201d and \u201cBrain Behavior and Immunity.\u201d The most cited article and co-cited reference was Cryan JF\u2019s 2012 article on the impact of gut microbiota on the brain and behavior. The current research hotspot includes gastrointestinal microbiome, inflammation, gut-brain axis, Parkinson\u2019s disease (PD), and Alzheimer\u2019s disease (AD). The research focus would be on the \u201cgastrointestinal microbiome, inflammation: a link between obesity, insulin resistance, and cognition\u201d and \u201cthe role of two important theories of the gut-brain axis and microbial-gut-brain axis in diseases.\u201d Burst detection analysis showed that schizophrenia, pathology, and psychiatric disorder may continue to be the research frontiers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Research on \u201cgastrointestinal microbiome, inflammation: a link between obesity, insulin resistance, and cognition\u201d and \u201cthe role of two important theories of the gut-brain axis and microbial-gut-brain axis in diseases\u201d will continue to be the hotspot. Schizophrenia and psychiatric disorder will be the key research diseases in the field of gut microbiota and neuroscience, and pathology is the key research content, which is worthy of scholars\u2019 attention.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnins.2022.1048565","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T15:21:26Z","timestamp":1668698486000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Mapping trends and hotspot regarding gastrointestinal microbiome and neuroscience: A bibliometric analysis of global research (2002\u20132022)"],"prefix":"10.3389","volume":"16","author":[{"given":"Jingjing","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihui","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzhe","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yixuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanyu","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dingxiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,11,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1017\/neu.2017.3","article-title":"Gut-brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease.","volume":"30","author":"Abautret-Daly","year":"2018","journal-title":"Acta Neuropsychiatr."},{"key":"B2","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.tics.2015.01.007","article-title":"The unsolved problems of neuroscience.","volume":"19","author":"Adolphs","year":"2015","journal-title":"Trends Cogn. 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