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Here, we examined whether hippocampal volume tracks normative variation in interpersonal family dynamics in 7- to 12-year-olds and adults recruited from the general population. We focused on interpersonal family dynamics as a prominent feature of one\u2019s social world. Given evidence that CA<jats:sub>1<\/jats:sub> and CA<jats:sub>2<\/jats:sub> play a key role in tracking social information, we related individual hippocampal subfield volumes to interpersonal family dynamics. More positive perceptions of interpersonal family dynamics were associated with greater CA<jats:sub>1<\/jats:sub> and CA<jats:sub>2\/3<\/jats:sub> volume regardless of age and controlling for socioeconomic status. These data suggest that CA subfields are sensitive to normative variation in social environments and identify interpersonal family dynamics as an impactful environmental feature.<\/jats:p>","DOI":"10.3389\/fnins.2022.872101","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T05:26:39Z","timestamp":1655443599000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Interpersonal Family Dynamics Relate to Hippocampal CA Subfield Structure"],"prefix":"10.3389","volume":"16","author":[{"given":"Christine","family":"Coughlin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliya","family":"Ben-Asher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah E.","family":"Roome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole L.","family":"Varga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle M.","family":"Moreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren L.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison R.","family":"Preston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,6,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10300","article-title":"Social and novel contexts modify hippocampal CA2 representations of space.","volume":"7","author":"Alexander","year":"2016","journal-title":"Nat. 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