{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T17:27:47Z","timestamp":1775755667491,"version":"3.50.1"},"reference-count":64,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T00:00:00Z","timestamp":1660867200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019349","name":"Nanjing Medical Science and Technique Development Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:p>Surgical treatment of vertigo is performed with in-depth study of inner ear diseases. Achieving an effective control of vertigo symptoms while reducing damage to hearing and reducing surgical complications is the principle followed by scholars studying surgical modalities. Semicircular canal occlusion is aimed at treatment of partial peripheral vertigo disease and has attracted the attention of scholars because of the above advantages. This article provides a review of the origins of semicircular canal occlusion, related basic research, clinical applications, and the effects of surgery on vestibular and hearing function.<\/jats:p>","DOI":"10.3389\/fnins.2022.977323","type":"journal-article","created":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T07:14:26Z","timestamp":1660893266000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Development of semicircular canal occlusion"],"prefix":"10.3389","volume":"16","author":[{"given":"Su","family":"Fei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Guangfei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Jie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gao","family":"Yiling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cai","family":"Mingjing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhang","family":"Qingxiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He","family":"Shuangba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,8,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1007\/BF01669801","article-title":"Ueber den einseitigen Drehschwindel\u201c","volume":"11","year":"1897","journal-title":"Deutsche Zeitschrift f\u00fcr Nervenheilkunde"},{"key":"B2","doi-asserted-by":"publisher","first-page":"102287","DOI":"10.1016\/j.amjoto.2019.102287","article-title":"Quality of life outcomes after transmastoid plugging of superior semicircular canal dehiscence","volume":"41","author":"Allsopp","year":"2020","journal-title":"Am. J. Otolaryngol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"434","DOI":"10.3109\/00016482009123103","article-title":"Diagnose yon Krankheitserscheinungen im Bereiche des Otolithenapparates","volume":"2","author":"B\u00e1r\u00e1ny","year":"1920","journal-title":"Acta Oto-Laryngol."},{"key":"B4","doi-asserted-by":"crossref","DOI":"10.1177\/0194599820909438","article-title":"Clinical practice guideline: M\u00e9ni\u00e8re's disease","volume-title":"Otolaryngol. Head Neck Surg","author":"Basura","year":"2020"},{"key":"B5","doi-asserted-by":"crossref","DOI":"10.1177\/0194599816689667","article-title":"Clinical practice guideline: benign paroxysmal positional vertigo (Update)","volume-title":"Otolaryngol. Head Neck Surg","author":"Bhattacharyya","year":"2017"},{"key":"B6","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3109\/00016489.2015.1087650","article-title":"A retrospective study on post-operative hearing of middle ear cholesteatoma patients with labyrinthine fistula","volume":"136","author":"Bo","year":"2016","journal-title":"Acta Otolaryngol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1080\/000164801300006308","article-title":"Symptoms, findings and treatment in patients with dehiscence of the superior semicircular canal","volume":"121","author":"Brantberg","year":"2001","journal-title":"Acta Otolaryngol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3109\/00016480902875083","article-title":"Surgical treatment of labyrinthine fistula caused by cholesteatoma with semicircular canal occlusion","volume":"130","author":"Chen","year":"2010","journal-title":"Acta Otolaryngol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1053\/ajot.2003.10","article-title":"Management of labyrinthine fistulae in chronic ear surgery","volume":"24","author":"Copeland","year":"2003","journal-title":"Am. J. Otolaryngol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1097\/MAO.0000000000002779","article-title":"A systematic review of cochlear implantation in temporal bone fractures and the significance of otic capsule involvement","volume":"41","author":"Cowan","year":"2020","journal-title":"Otol. Neurotol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"e1691","DOI":"10.1097\/MAO.0000000000003238","article-title":"Hearing outcomes for an underwater endoscopic technique for transmastoid repair of superior semicircular canal dehiscence","volume":"42","author":"Creighton","year":"2021","journal-title":"Otol. Neurotol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"2919463","DOI":"10.1155\/2017\/2919463","article-title":"Diagnostic bedside vestibuloocular reflex evaluation in the setting of a false negative fistula test in cholesteatoma of the middle ear","volume":"2017","author":"D'Albora","year":"2017","journal-title":"Case Rep. Otolaryngol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1097\/MAO.0000000000003329","article-title":"Transmastoid occlusion surgery for superior semicircular canal dehiscence syndrome improves patient-reported quality-of-life measures and corrects cVEMP thresholds and amplitudes","volume":"42","author":"de Wolf","year":"2021","journal-title":"Otol. Neurotol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1177\/003591575204500604","article-title":"The pathology symptomatology and diagnosis of certain common disorders of the vestibular system","volume":"45","author":"Dix","year":"1952","journal-title":"Proc. R. Soc. Med."},{"key":"B15","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/S0194-5998(95)70275-X","article-title":"Management of the open labyrinth","volume":"112","author":"Dornhoffer","year":"1995","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"B16","doi-asserted-by":"publisher","first-page":"167","DOI":"10.3760\/cma.j.issn.1673-0860.2017.03.002","article-title":"Guideline of diagnosis and treatment of Meniere disease (2017)","volume":"52","year":"2017","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"B17","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1097\/MAO.0000000000003350","article-title":"Intraoperative electrocochleography correlates to outcomes in transmastoid and middle cranial fossa superior semicircular canal dehiscence repair","volume":"43","author":"Ellsperman","year":"2022","journal-title":"Otol. Neurotol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1177\/000348947408300504","article-title":"Transection of the posterior ampullary nerve for the relief of benign paroxysmal positional vertigo","volume":"83","author":"Gacek","year":"1974","journal-title":"Ann. Otol. Rhinol. Laryngol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1177\/00034894840930S405","article-title":"Cupulolithiasis and posterior ampullary nerve transection","volume":"112","author":"Gacek","year":"1984","journal-title":"Ann. Otol. Rhinol. Laryngol. Suppl"},{"key":"B20","first-page":"11","article-title":"Lateral semicircular canal plugging: a simple and effective surgical treatment against incapacitating Meni\u00e8re's disease","volume-title":"Rev. Laryngol. Otol. Rhinol. (Bord)","author":"Gentine","year":"2008"},{"key":"B21","doi-asserted-by":"crossref","DOI":"10.1007\/s00405-022-07316-8","article-title":"Evaluation of the transmastoid plugging approach for superior semicircular canal dehiscences: a retrospective series of 30 ears","volume-title":"Eur. Arch. Otorhinolaryngol.","author":"Gersdorff","year":"2022"},{"key":"B22","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/S0196-0709(00)80072-1","article-title":"Labyrinthine fistula after cholesteatomatous chronic otitis media","volume":"21","author":"Gersdorff","year":"2000","journal-title":"Am. J. Otol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1097\/MAO.0000000000002841","article-title":"Triple Canal occlusion for the treatment of intractable Meni\u00e8re's disease","volume":"42","author":"Gill","year":"2021","journal-title":"Otol. Neurotol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1177\/003591573803101112","article-title":"Observations on the pathology of M\u00e9ni\u00e8re's syndrome: (Section of Otology)","volume":"31","author":"Hallpike","year":"1938","journal-title":"Proc. R. Soc. Med"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1017\/S0022215119002032","article-title":"Gauging the effectiveness of canal occlusion surgery: how I do it","volume":"133","author":"Hassannia","year":"2019","journal-title":"J. Laryngol. Otol."},{"key":"B26","first-page":"15","article-title":"Histopathology of labyrinthine fistulae in chronic otitis media with clinical implications","volume":"18","author":"Jang","year":"1997","journal-title":"Am. J. Otol."},{"key":"B27","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.797699","article-title":"Changes of vestibular symptoms in meni\u00e8re's disease after triple semicircular canal occlusion: a long-term follow-up study","volume-title":"Front. Neurol","author":"Jiang","year":"2022"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1177\/00034894211007245","article-title":"Reversible canalith jam of the horizontal semicircular canal mimicking cupulolithiasis","volume":"130","author":"Kalmanson","year":"2021","journal-title":"Ann. Otol. Rhinol. Laryngol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/s00415-011-6130-x","article-title":"The Tullio phenomenon: a neurologically neglected presentation","volume":"259","author":"Kaski","year":"2012","journal-title":"J. Neurol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1097\/MAO.0000000000003191","article-title":"Transmastoid superior semicircular canal plugging: a prospective analysis of surgical outcomes","volume":"42","author":"Kontorinis","year":"2021","journal-title":"Otol. Neurotol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1017\/S002221512100387X","article-title":"Triple semicircular canal occlusion: a surgical perspective with short- and long-term outcomes","volume":"136","author":"Kontorinis","year":"2022","journal-title":"J. Laryngol. Otol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1097\/MAO.0000000000003100","article-title":"Hearing outcomes after surgical manipulation of the membranous labyrinth during superior semicircular canal dehiscence plugging or posterior semicircular canal occlusion","volume":"42","author":"Lin","year":"2021","journal-title":"Otol. Neurotol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jocn.2017.11.019","article-title":"Superior semicircular canal dehiscence: diagnosis and management","volume":"48","author":"Mau","year":"2018","journal-title":"J. Clin. Neurosci."},{"key":"B34","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/S0196-0709(00)80068-X","article-title":"Superior canal dehiscence syndrome","volume":"21","author":"Minor","year":"2000","journal-title":"Am. J. Otol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1001\/archotol.124.3.249","article-title":"Sound- and\/or pressure-induced vertigo due to bone dehiscence of the superior semicircular canal","volume":"124","author":"Minor","year":"1998","journal-title":"Arch. Otolaryngol. Head Neck Surg"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1007\/s00405-013-2533-x","article-title":"Surgical capping of superior semicircular canal dehiscence","volume":"271","author":"Mueller","year":"2014","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"B37","first-page":"77","article-title":"Concomitant treatment of superior semicircular canal and tegmen dehiscence by transmastoid approach (with video)","volume-title":"Eur. Ann. Otorhinolaryngol. Head Neck. Dis.","author":"Nieto","year":"2021"},{"key":"B38","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1159\/000276077","article-title":"Surgical management of labyrinthine fistulae in chronic otitis media with cholesteatoma by a one-stage closed technique","volume":"51","author":"Ostri","year":"1989","journal-title":"ORL J. Otorhinolaryngol. Relat. Spec."},{"key":"B39","doi-asserted-by":"publisher","first-page":"804915","DOI":"10.3389\/fneur.2022.804915","article-title":"Labyrinthine fistula in cholesteatoma patients: outcomes of partial labyrinthectomy with \u201cUnderwater Technique\u201d to preserve hearing","volume":"13","author":"Pace","year":"2022","journal-title":"Front. Neurol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/S0030-6665(20)30396-0","article-title":"Update on posterior canal occlusion for benign paroxysmal positional vertigo","volume":"29","author":"Parnes","year":"1996","journal-title":"Otolaryngol. Clin. North Am"},{"key":"B41","first-page":"330","article-title":"Posterior semicircular canal occlusion for intractable benign paroxysmal positional vertigo","volume-title":"Ann. Otol. Rhinol. Laryngol","author":"Parnes","year":"1990"},{"key":"B42","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1097\/MOO.0b013e3283646467","article-title":"Current trends in the management of the complications of chronic otitis media with cholesteatoma","volume":"21","author":"Prasad","year":"2013","journal-title":"Curr. Opin. Otolaryngol. Head Neck Surg."},{"key":"B43","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.otohns.2008.11.028","article-title":"Surgical treatment of labyrinthine fistula in cholesteatoma surgery","volume":"140","author":"Quaranta","year":"2009","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"B44","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1097\/00129492-200405000-00021","article-title":"Clinical, experimental, and theoretical investigations of the effect of superior semicircular canal dehiscence on hearing mechanisms","volume":"25","author":"Rosowski","year":"2004","journal-title":"Otol. Neurotol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/S0140-6736(08)61161-7","article-title":"Meniere's disease","volume":"372","author":"Sajjadi","year":"2008","journal-title":"Lancet"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1002\/ar.24675","article-title":"Three-dimensional visualization of the human membranous labyrinth: The membrana limitans and its role in vestibular form","volume":"305","author":"Smith","year":"2022","journal-title":"Anat. Rec. (Hoboken)"},{"key":"B47","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1055\/s-0039-3402738","article-title":"Superior Semicircular Canal Dehiscence Syndrome","volume":"40","author":"Steenerson","year":"2020","journal-title":"Semin. Neurol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1007\/s00405-011-1545-7","article-title":"Prognostic indicators of hearing after complete resection of cholesteatoma causing a labyrinthine fistula","volume":"268","author":"Stephenson","year":"2011","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"B49","doi-asserted-by":"crossref","DOI":"10.1007\/s00415-021-10693-5","article-title":"The resilience of the inner ear-vestibular and audiometric impact of transmastoid semicircular canal plugging","volume-title":"J. Neurol.","author":"Stultiens","year":"2021"},{"key":"B50","doi-asserted-by":"publisher","first-page":"3355","DOI":"10.1007\/s00405-021-07058-z","article-title":"Post-operative hearing among patients with labyrinthine fistula as a complication of cholesteatoma using \u201cunder water technique\u201d","volume":"279","author":"Thangavelu","year":"2022","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1017\/S0022215121004308","article-title":"Superior semicircular canal dehiscence repair with small middle fossa craniotomy using an oto-microscopic and co-endoscopic assisted approach","volume":"136","author":"Tugrul","year":"2022","journal-title":"J. Laryngol. Otol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.anl.2011.06.005","article-title":"Transient low-tone air-bone gaps during convalescence immediately after canal plugging surgery for BPPV","volume":"39","author":"Uetsuka","year":"2012","journal-title":"Auris Nasus Larynx"},{"key":"B53","doi-asserted-by":"publisher","first-page":"5099","DOI":"10.1007\/s00405-021-07095-8","article-title":"Transcanal endoscopic management of lateral semicircular canal fistula: preliminary experience","volume":"278","author":"Villari","year":"2021","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/s00405-008-0840-4","article-title":"Efficacy assessment and complications of surgical management for superior semicircular canal dehiscence: a meta-analysis of published interventional studies","volume":"266","author":"Vlastarakos","year":"2009","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1046\/j.1365-2273.1999.00266.x","article-title":"Long-term results of posterior semicircular canal occlusion for intractable benign paroxysmal positional vertigo","volume":"24","author":"Walsh","year":"1999","journal-title":"Clin. Otolaryngol. Allied. Sci"},{"key":"B56","doi-asserted-by":"publisher","first-page":"177","DOI":"10.3389\/fneur.2017.00177","article-title":"Superior canal dehiscence syndrome: lessons from the first 20 years","volume":"8","author":"Ward","year":"2017","journal-title":"Front. Neurol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"2616","DOI":"10.1002\/lary.24785","article-title":"Closure technique for labyrinthine fistula by \u201cunderwater\u201d endoscopic ear surgery","volume":"124","author":"Yamauchi","year":"2014","journal-title":"Laryngoscope"},{"key":"B58","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1080\/00016480701730000","article-title":"Triple semicircular canal occlusion for the treatment of M\u00e9ni\u00e8re's disease","volume":"128","author":"Yin","year":"2008","journal-title":"Acta Otolaryngol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1097\/01.mao.0000170535.42023.96","article-title":"Triple semicircular canal occlusion in guinea pigs with endolymphatic hydrops","volume":"27","author":"Yin","year":"2006","journal-title":"Otol. Neurotol"},{"key":"B60","article-title":"Surgical procedures of vertigo disease","volume-title":"J Clin Otorhinolaryngol Head Neck Surg","author":"Zhang","year":"2014"},{"key":"B61","doi-asserted-by":"publisher","first-page":"446","DOI":"10.3969\/j.issn.1672-2922.2016.04.002","article-title":"Various approaches in semicircular canal plugging for treatment of intractable Meniere's disease","volume":"14","author":"Zhang","year":"2016","journal-title":"Chin. J Otol."},{"key":"B62","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-55810-7","article-title":"Revision surgery after triple semicircular canal plugging and morphologic changes of vestibular organ","volume-title":"Sci Rep","author":"Zhang","year":"2019"},{"key":"B63","doi-asserted-by":"publisher","first-page":"3846","DOI":"10.1039\/C5AN00110B","article-title":"Unilateral horizontal semicircular canal occlusion induces serotonin increase in medial vestibular nuclei: a study using microdialysis in vivo coupled with HPLC-ECD","volume":"140","author":"Zhang","year":"2015","journal-title":"Analyst"},{"key":"B64","doi-asserted-by":"publisher","first-page":"713275","DOI":"10.3389\/fneur.2021.713275","article-title":"Case report: preservation of otolithic function after triple semicircular canal occlusion in a patient with intractable M\u00e9ni\u00e8re disease","volume":"12","author":"Zhang","year":"2021","journal-title":"Front. Neurol."}],"container-title":["Frontiers in Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnins.2022.977323\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T07:14:38Z","timestamp":1660893278000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnins.2022.977323\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,19]]},"references-count":64,"alternative-id":["10.3389\/fnins.2022.977323"],"URL":"https:\/\/doi.org\/10.3389\/fnins.2022.977323","relation":{},"ISSN":["1662-453X"],"issn-type":[{"value":"1662-453X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,19]]},"article-number":"977323"}}