{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:02:34Z","timestamp":1777622554605,"version":"3.51.4"},"reference-count":70,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Sudden sensorineural hearing loss (SSHL) is a critical otologic emergency characterized by a rapid decline of at least 30 dB across three consecutive frequencies in the pure-tone audiogram within a 72-hour period. This audiological condition has been associated with alterations in brain cortical and subcortical structures, as well as changes in brain functional activities involving multiple networks. However, the extent of cerebral intrinsic brain activity disruption in SSHL remains poorly understood. The aimed of this study is to investigate intrinsic brain activity alterations in SSHL using static and dynamic fractional amplitude of low-frequency fluctuation (fALFF) analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Resting-state functional magnetic resonance imaging (fMRI) data were acquired from a cohort of SSHL patients (unilateral, <jats:italic>n<\/jats:italic> = 102) and healthy controls (<jats:italic>n<\/jats:italic> = 73). Static and dynamic fALFF methods were employed to analyze the acquired fMRI data, enabling a comprehensive examination of intrinsic brain activity changes in SSHL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our analysis revealed significant differences in static fALFF patterns between SSHL patients and healthy controls. SSHL patients exhibited decreased fALFF in the left fusiform gyrus, left precentral gyrus, and right inferior frontal gyrus, alongside increased fALFF in the left inferior frontal gyrus, left superior frontal gyrus, and right middle temporal gyrus. Additionally, dynamic fALFF analysis demonstrated elevated fALFF in the right superior frontal gyrus and right middle frontal gyrus among SSHL patients. Intriguingly, we observed a positive correlation between static fALFF in the left fusiform gyrus and the duration of hearing loss, shedding light on potential temporal dynamics associated with intrinsic brain activity changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The observed disruptions in intrinsic brain activity and temporal dynamics among SSHL patients provide valuable insights into the functional reorganization and potential compensatory mechanisms linked to hearing loss. These findings underscore the importance of understanding the underlying neural alterations in SSHL, which could pave the way for the development of targeted interventions and rehabilitation strategies aimed at optimizing SSHL management.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnins.2023.1257729","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T10:12:56Z","timestamp":1693476776000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Altered static and dynamic intrinsic brain activity in unilateral sudden sensorineural hearing loss"],"prefix":"10.3389","volume":"17","author":[{"given":"Jing","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaocheng","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangming","family":"Leng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenliang","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1097\/MAO.0000000000000222","article-title":"Incidence of sudden sensorineural hearing loss","volume":"34","author":"Alexander","year":"2013","journal-title":"Otol. Neurotol."},{"key":"ref2","first-page":"272","article-title":"Does the addition of a second daily session of hyperbaric oxygen therapy to intratympanic steroid influence the outcomes of sudden hearing loss?","volume":"35","author":"Attanasio","year":"2015","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1002\/ca.23523","article-title":"Anatomy and white matter connections of the superior frontal gyrus","volume":"33","author":"Briggs","year":"2020","journal-title":"Clin. Anat."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e520","DOI":"10.1016\/j.wneu.2021.03.045","article-title":"Anatomy and white matter connections of the middle frontal gyrus","volume":"150","author":"Briggs","year":"2021","journal-title":"World Neurosurg."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1080\/00016480260094947","article-title":"Autoimmunity in sudden sensorineural hearing loss: possible role of anti-endothelial cell autoantibodies","volume":"122","author":"Cadoni","year":"2002","journal-title":"Acta Otolaryngol. Suppl."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1177\/0194599819859885","article-title":"Clinical practice guideline: sudden hearing loss (update)","volume":"161","author":"Chandrasekhar","year":"2019","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2020\/9460364","article-title":"Altered brain activity and functional connectivity in unilateral sudden sensorineural hearing loss","volume":"2020","author":"Chen","year":"2020","journal-title":"Neural Plast."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"113980","DOI":"10.1016\/j.bbr.2022.113980","article-title":"Altered dynamic amplitude of low-frequency fluctuations in patients with postpartum depression","volume":"433","author":"Dong","year":"2022","journal-title":"Behav. Brain Res."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"3315","DOI":"10.1093\/brain\/awl244","article-title":"Functions of the left superior frontal gyrus in humans: a lesion study","volume":"129","author":"Du Boisgueheneuc","year":"2006","journal-title":"Brain"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"2214","DOI":"10.1093\/brain\/awab447","article-title":"3T MRI of rapid brain activity changes driven by subcallosal cingulate deep brain stimulation","volume":"145","author":"Elias","year":"2022","journal-title":"Brain"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.1097\/MAO.0000000000000892","article-title":"Altered contralateral auditory cortical morphology in unilateral sudden sensorineural hearing loss","volume":"36","author":"Fan","year":"2015","journal-title":"Otol. Neurotol."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"900","DOI":"10.3109\/00016489.2013.788791","article-title":"Long-term results of intratympanic prednisolone injection in patients with idiopathic sudden sensorineural hearing loss","volume":"133","author":"Filipo","year":"2013","journal-title":"Acta Otolaryngol."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1176\/appi.ajp.2019.19050560","article-title":"Multimodal abnormalities of brain structure and function in major depressive disorder: a meta-analysis of neuroimaging studies","volume":"177","author":"Gray","year":"2020","journal-title":"Am. J. Psychiatry"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1016\/j.neuroimage.2009.12.109","article-title":"The role of the right inferior frontal gyrus: inhibition and attentional control","volume":"50","author":"Hampshire","year":"2010","journal-title":"Neuroimage"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"e05658","DOI":"10.1016\/j.heliyon.2020.e05658","article-title":"Reduced grey- and white matter volumes due to unilateral hearing loss following treatment for vestibular schwannoma","volume":"6","author":"Heggdal","year":"2020","journal-title":"Heliyon"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"898902","DOI":"10.3389\/fnins.2022.898902","article-title":"Aberrant functional network of small-world in sudden sensorineural hearing loss with tinnitus","volume":"16","author":"Hua","year":"2022","journal-title":"Front. Neurosci."},{"key":"ref17","doi-asserted-by":"publisher","first-page":"685","DOI":"10.3389\/fpsyg.2020.00685","article-title":"Anterior and posterior left inferior frontal gyrus contribute to the implementation of grammatical determiners during language production","volume":"11","author":"Ishkhanyan","year":"2020","journal-title":"Front. Psychol."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1159\/000485313","article-title":"A trend in sudden sensorineural hearing loss: data from a population-based study","volume":"22","author":"Kim","year":"2017","journal-title":"Audiol. Neurootol."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1177\/1084713811408349","article-title":"Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis","volume":"15","author":"Kuhn","year":"2011","journal-title":"Trends Amplif."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1080\/14992027.2019.1627009","article-title":"Increased incidence in hospitalised patients with sudden sensorineural hearing loss: a 14-year nationwide population-based study","volume":"58","author":"Kuo","year":"2019","journal-title":"Int. J. Audiol."},{"key":"ref21","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1002\/ccr3.510","article-title":"Concurrent hyperbaric oxygen therapy and intratympanic steroid application as salvage therapy after severe sudden sensorineural hearing loss","volume":"4","author":"Lamm","year":"2016","journal-title":"Clin. Case Rep."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1007\/s00405-015-3689-3","article-title":"Intratympanic corticosteroids injections: a systematic review of literature","volume":"273","author":"Lavigne","year":"2016","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1111\/coa.12363","article-title":"Controversies in the management of sudden sensorineural hearing loss: an evidence-based review","volume":"40","author":"Lawrence","year":"2015","journal-title":"Clin. Otolaryngol."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"152144","DOI":"10.1016\/j.comppsych.2019.152144","article-title":"Altered spontaneous brain activity in obsessive-compulsive personality disorder","volume":"96","author":"Lei","year":"2020","journal-title":"Compr. Psychiatry"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1002\/lio2.876","article-title":"Vascular loops in cerebellopontine angle in patients with unilateral idiopathic sudden sensorineural hearing loss: evaluations by three radiological grading systems","volume":"7","author":"Leng","year":"2022","journal-title":"Laryngoscope Investig. Otolaryngol."},{"key":"ref26","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.neuroimage.2014.09.007","article-title":"On spurious and real fluctuations of dynamic functional connectivity during rest","volume":"104","author":"Leonardi","year":"2015","journal-title":"Neuroimage"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"136470","DOI":"10.1016\/j.neulet.2022.136470","article-title":"Dynamic alterations of functional connectivity and amplitude of low-frequency fluctuations in patients with unilateral sudden sensorineural hearing loss","volume":"772","author":"Li","year":"2022","journal-title":"Neurosci. Lett."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1177\/1060028020908067","article-title":"Effectiveness of steroid treatment for sudden sensorineural hearing loss: a meta-analysis of randomized controlled trials","volume":"54","author":"Li","year":"2020","journal-title":"Ann. Pharmacother."},{"key":"ref29","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1017\/S0033291718001502","article-title":"More than just statics: temporal dynamics of intrinsic brain activity predicts the suicidal ideation in depressed patients","volume":"49","author":"Li","year":"2019","journal-title":"Psychol. Med."},{"key":"ref30","doi-asserted-by":"publisher","first-page":"63","DOI":"10.21037\/atm-20-7214","article-title":"Temporal dynamic changes of intrinsic brain activity in Alzheimer's disease and mild cognitive impairment patients: a resting-state functional magnetic resonance imaging study","volume":"9","author":"Li","year":"2021","journal-title":"Ann. Transl. Med."},{"key":"ref31","doi-asserted-by":"publisher","first-page":"678359","DOI":"10.3389\/fnagi.2021.678359","article-title":"Regional spontaneous neural activity alterations in type 2 diabetes mellitus: a meta-analysis of resting-state functional MRI studies","volume":"13","author":"Liu","year":"2021","journal-title":"Front. Aging Neurosci."},{"key":"ref32","doi-asserted-by":"publisher","first-page":"387","DOI":"10.3233\/JAD-131322","article-title":"Abnormal amplitude of low-frequency fluctuations of intrinsic brain activity in Alzheimer's disease","volume":"40","author":"Liu","year":"2014","journal-title":"J. Alzheimers Dis."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"e45470","DOI":"10.1371\/journal.pone.0045470","article-title":"Patterns of spontaneous brain activity in amyotrophic lateral sclerosis: a resting-state FMRI study","volume":"7","author":"Luo","year":"2012","journal-title":"PLoS One"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"e10052","DOI":"10.7717\/peerj.10052","article-title":"Static and dynamic alterations in the amplitude of low-frequency fluctuation in patients with amyotrophic lateral sclerosis","volume":"8","author":"Ma","year":"","journal-title":"PeerJ"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"733","DOI":"10.3389\/fnins.2020.00733","article-title":"Static and dynamic changes of amplitude of low-frequency fluctuations in cervical discogenic pain","volume":"14","author":"Ma","year":"","journal-title":"Front. Neurosci."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"9995","DOI":"10.1038\/s41598-023-36192-3","article-title":"Transcranial magnetic stimulation of the left middle frontal gyrus modulates the information people communicate in different social contexts","volume":"13","author":"Martin-Luengo","year":"2023","journal-title":"Sci. Rep."},{"key":"ref37","doi-asserted-by":"publisher","first-page":"e4544","DOI":"10.1002\/nbm.4544","article-title":"Global and local brain connectivity changes associated with sudden unilateral sensorineural hearing loss","volume":"34","author":"Minosse","year":"2021","journal-title":"NMR Biomed."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"e100147","DOI":"10.1136\/gpsych-2019-100147","article-title":"Amplitude of low-frequency fluctuations on Alzheimer's disease with depression: evidence from resting-state fMRI","volume":"33","author":"Mu","year":"2020","journal-title":"Gen. Psychiatr."},{"key":"ref39","doi-asserted-by":"publisher","first-page":"108565","DOI":"10.1016\/j.heares.2022.108565","article-title":"Idiopathic sudden sensorineural hearing loss: a critique on corticosteroid therapy","volume":"422","author":"Murray","year":"2022","journal-title":"Hear. Res."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.neuron.2020.05.007","article-title":"Plasticity and spontaneous activity pulses in disused human brain circuits","volume":"107","author":"Newbold","year":"2020","journal-title":"Neuron"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1001\/archotol.1996.01890140029007","article-title":"Development of the tinnitus handicap inventory","volume":"122","author":"Newman","year":"1996","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1001\/jamaneurol.2013.38","article-title":"Resting-state functional magnetic resonance imaging activity and connectivity and cognitive outcome in traumatic brain injury","volume":"70","author":"Palacios","year":"2013","journal-title":"JAMA Neurol."},{"key":"ref43","doi-asserted-by":"publisher","first-page":"13489","DOI":"10.1038\/s41598-020-70410-6","article-title":"Anatomy and white matter connections of the fusiform gyrus","volume":"10","author":"Palejwala","year":"2020","journal-title":"Sci. Rep."},{"key":"ref44","doi-asserted-by":"publisher","first-page":"40469","DOI":"10.1038\/srep40469","article-title":"Abnormalities of regional brain function in Parkinson's disease: a meta-analysis of resting state functional magnetic resonance imaging studies","volume":"7","author":"Pan","year":"2017","journal-title":"Sci. Rep."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"CD008080","DOI":"10.1002\/14651858.cd008080.pub2","article-title":"Intratympanic corticosteroids for sudden sensorineural hearing loss","volume":"7","author":"Plontke","year":"2022","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"935834","DOI":"10.3389\/fnins.2022.935834","article-title":"Intrinsic brain activity reorganization contributes to long-term compensation of higher-order hearing abilities in single-sided deafness","volume":"16","author":"Qiao","year":"2022","journal-title":"Front. Neurosci."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"372","DOI":"10.4306\/pi.2015.12.3.372","article-title":"Analysis of altered baseline brain activity in drug-naive adult patients with social anxiety disorder using resting-state functional MRI","volume":"12","author":"Qiu","year":"2015","journal-title":"Psychiatry Investig."},{"key":"ref48","doi-asserted-by":"publisher","first-page":"565445","DOI":"10.3389\/fnhum.2020.565445","article-title":"Alteration of cortical and subcortical structures in children with profound sensorineural hearing loss","volume":"14","author":"Qu","year":"2020","journal-title":"Front. Hum. Neurosci."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1016\/S0140-6736(09)62071-7","article-title":"Sudden sensorineural hearing loss","volume":"375","author":"Schreiber","year":"2010","journal-title":"Lancet"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"8416","DOI":"10.1523\/JNEUROSCI.1614-22.2022","article-title":"A neurosurgical functional dissection of the middle precentral gyrus during speech production","volume":"42","author":"Silva","year":"2022","journal-title":"J. Neurosci."},{"key":"ref51","doi-asserted-by":"publisher","first-page":"105233","DOI":"10.1016\/j.bandl.2023.105233","article-title":"Word-producing brain: contribution of the left anterior middle temporal gyrus to word production patterns in spoken language","volume":"238","author":"Sugimoto","year":"2023","journal-title":"Brain Lang."},{"key":"ref52","doi-asserted-by":"publisher","first-page":"3028","DOI":"10.1038\/s41467-018-05432-w","article-title":"Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion","volume":"9","author":"Sui","year":"2018","journal-title":"Nat. Commun."},{"key":"ref53","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1515\/jbcpp-2015-0112","article-title":"Efficacy of oral vs. intratympanic corticosteroids in sudden sensorineural hearing loss","volume":"27","author":"Swachia","year":"2016","journal-title":"J. Basic Clin. Physiol. Pharmacol."},{"key":"ref54","doi-asserted-by":"publisher","first-page":"719254","DOI":"10.3389\/fnhum.2021.719254","article-title":"Functional magnetic resonance imaging reveals early connectivity changes in the auditory and vestibular cortices in idiopathic sudden sensorineural hearing loss with vertigo: a pilot study","volume":"15","author":"Wang","year":"2021","journal-title":"Front. Hum. Neurosci."},{"key":"ref55","doi-asserted-by":"publisher","first-page":"152","DOI":"10.3389\/fnagi.2019.00152","article-title":"Altered static and temporal dynamic amplitude of low-frequency fluctuations in the background network during working memory states in mild cognitive impairment","volume":"11","author":"Wang","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"ref56","doi-asserted-by":"publisher","first-page":"792695","DOI":"10.3389\/fneur.2022.792695","article-title":"Structural and functional asymmetry in precentral and postcentral gyrus in patients with unilateral chronic shoulder pain","volume":"13","author":"Wei","year":"2022","journal-title":"Front. Neurol."},{"key":"ref57","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.neuropsychologia.2015.06.033","article-title":"The anatomical and functional specialization of the fusiform gyrus","volume":"83","author":"Weiner","year":"2016","journal-title":"Neuropsychologia"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"206","DOI":"10.3389\/fnins.2019.00206","article-title":"Differences in intrinsic brain abnormalities between patients with left- and right-sided Long-term hearing impairment","volume":"13","author":"Xie","year":"2019","journal-title":"Front. Neurosci."},{"key":"ref59","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.heares.2016.02.016","article-title":"Disrupted functional brain connectome in unilateral sudden sensorineural hearing loss","volume":"335","author":"Xu","year":"2016","journal-title":"Hear. Res."},{"key":"ref60","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.neuroimage.2013.04.081","article-title":"Standardizing the intrinsic brain: towards robust measurement of inter-individual variation in 1000 functional connectomes","volume":"80","author":"Yan","year":"2013","journal-title":"Neuroimage"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s12021-016-9299-4","article-title":"DPABI: Data Processing & Analysis for (resting-state) brain imaging","volume":"14","author":"Yan","year":"2016","journal-title":"Neuroinformatics"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1016\/j.scib.2017.09.015","article-title":"Concordance among indices of intrinsic brain function: insights from inter-individual variation and temporal dynamics","volume":"62","author":"Yan","year":"2017","journal-title":"Sci. Bull."},{"key":"ref63","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.heares.2014.07.006","article-title":"Brain structural and functional alterations in patients with unilateral hearing loss","volume":"316","author":"Yang","year":"2014","journal-title":"Hear. Res."},{"key":"ref64","doi-asserted-by":"publisher","first-page":"102819","DOI":"10.1016\/j.nicl.2021.102819","article-title":"Altered regional activity and connectivity of functional brain networks in congenital unilateral conductive hearing loss","volume":"32","author":"Yang","year":"2021","journal-title":"Neuroimage Clin."},{"key":"ref65","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.jad.2022.07.043","article-title":"Aberrant brain dynamics in major depressive disorder with suicidal ideation","volume":"314","author":"Yang","year":"2022","journal-title":"J. Affect. Disord."},{"key":"ref66","doi-asserted-by":"publisher","first-page":"100915","DOI":"10.1016\/j.yfrne.2021.100915","article-title":"A multimodal meta-analysis of regional structural and functional brain alterations in type 2 diabetes","volume":"62","author":"Yao","year":"2021","journal-title":"Front. Neuroendocrinol."},{"key":"ref67","doi-asserted-by":"publisher","first-page":"105162","DOI":"10.1016\/j.bandl.2022.105162","article-title":"The posterior middle temporal gyrus serves as a hub in syntactic comprehension: a model on the syntactic neural network","volume":"232","author":"Yu","year":"2022","journal-title":"Brain Lang."},{"key":"ref68","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.3389\/fnins.2019.01010","article-title":"Disrupted intraregional brain activity and functional connectivity in unilateral acute tinnitus patients with hearing loss","volume":"13","author":"Zhou","year":"2019","journal-title":"Front. Neurosci."},{"key":"ref69","doi-asserted-by":"publisher","first-page":"e63","DOI":"10.1016\/j.acra.2020.02.020","article-title":"Characterizing static and dynamic fractional amplitude of low-frequency fluctuation and its prediction of clinical dysfunction in patients with diffuse axonal injury","volume":"28","author":"Zhou","year":"2021","journal-title":"Acad. Radiol."},{"key":"ref70","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.jneumeth.2008.04.012","article-title":"An improved approach to detection of amplitude of low-frequency fluctuation (ALFF) for resting-state fMRI: fractional ALFF","volume":"172","author":"Zou","year":"2008","journal-title":"J. Neurosci. Methods"}],"container-title":["Frontiers in Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnins.2023.1257729\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T10:13:00Z","timestamp":1693476780000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnins.2023.1257729\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":70,"alternative-id":["10.3389\/fnins.2023.1257729"],"URL":"https:\/\/doi.org\/10.3389\/fnins.2023.1257729","relation":{},"ISSN":["1662-453X"],"issn-type":[{"value":"1662-453X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,31]]},"article-number":"1257729"}}