{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T01:38:59Z","timestamp":1793151539919,"version":"4.5.0"},"reference-count":77,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:00:00Z","timestamp":1725580800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Alzheimer\u2019s disease (AD) prevalence has increased in the last century which can be attributed to increased lifespan, but environment is also important. Exposure to artificial light at night is one environmental factor that may influence AD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study evaluated the relationship between outdoor nighttime light exposure and AD prevalence in the United States using satellite acquired outdoor nighttime light intensity and Medicare data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Higher outdoor nighttime light was associated with higher prevalence of AD. While atrial fibrillation, diabetes, hyperlipidemia, hypertension, and stroke were associated more strongly with AD prevalence than nighttime light intensity, nighttime light was more strongly associated with AD prevalence than alcohol abuse, chronic kidney disease, depression, heart failure, and obesity. Startlingly, nighttime light exposure more strongly associated with AD prevalence in those under the age of 65 than any other disease factor examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These data suggest light exposure at night may influence AD, but additional studies are needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnins.2024.1378498","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:19:56Z","timestamp":1725581996000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Outdoor nighttime light exposure (light pollution) is associated with Alzheimer\u2019s disease"],"prefix":"10.3389","volume":"18","author":[{"given":"Robin M.","family":"Voigt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bichun","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Keshavarzian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"j2856","DOI":"10.1136\/bmj.j2856","article-title":"Temporal trend in dementia incidence since 2002 and projections for prevalence in England and Wales to 2040: modelling study","volume":"358","author":"Ahmadi-Abhari","year":"2017","journal-title":"BMJ"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"igx034","DOI":"10.1093\/geroni\/igx034","article-title":"Arab American cognitive aging: opportunities for advancing research on Alzheimer's disease disparities","volume":"1","author":"Ajrouch","year":"2017","journal-title":"Innov. 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Psychiatry"},{"key":"ref9","volume-title":"Lengthening the day: a history of lighting technology","author":"Bowers","year":"1998"},{"key":"ref10","volume-title":"The way home: tales from a life without technology","author":"Boyle","year":"2019"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"115049","DOI":"10.1016\/j.envres.2022.115049","article-title":"Outdoor artificial light at night and human health: a review of epidemiological studies","volume":"218","author":"Bozejko","year":"2023","journal-title":"Environ. 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Med."},{"key":"ref63","volume-title":"Disenchanted night: The industrialization of light in the Nineteeth century","author":"Schivelbusch","year":"1995"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1212\/WNL.0b013e3182553be6","article-title":"Is dementia incidence declining?: trends in dementia incidence since 1990 in the Rotterdam study","volume":"78","author":"Schrijvers","year":"2012","journal-title":"Neurology"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1093\/gerona\/gly236","article-title":"Declining incident dementia rates across four population-based birth cohorts","volume":"74","author":"Sullivan","year":"2019","journal-title":"J. Gerontol. A Biol. Sci. Med. 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