{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T03:06:37Z","timestamp":1773198397240,"version":"3.50.1"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Qinghai Provincial Basic Research Program in Science and Technology"],"award-info":[{"award-number":["Qinghai Provincial Basic Research Program in Science and Technology"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["National Natural Science Foundation of China"],"award-info":[{"award-number":["National Natural Science Foundation of China"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Major Science and Technology Special Projects of Qinghai Province"],"award-info":[{"award-number":["Major Science and Technology Special Projects of Qinghai Province"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study investigated the effects of chronic high-altitude exposure on memory function and neural processing in indigenous highland junior high school students.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Three altitude groups were established\u2013low (1,400 m), mid (2,800 m), and high (4,200 m). A delayed recognition task dissociated memory encoding, maintenance, and retrieval stages. Physiological (blood oxygen saturation, heart rate, vital capacity), behavioral, and electroencephalographic measures were employed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Physiological: Blood oxygen saturation, heart rate, and maximal vital capacity decreased with increasing altitude. Behavioral: The high-altitude group showed lower recognition discriminability and more conservative decision-making vs. lower-altitude groups. Electrophysiological: High-altitude subjects exhibited reduced encoding-related attention, altered maintenance activity, and attenuated early retrieval attention. Correlation analyses linked blood oxygen saturation to behavioral discriminability and event-related potential components across memory stages.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Chronic hypoxic exposure associates with stage-specific alterations in memory-related neural and behavioral performance in adolescent highlanders. While more pronounced impairments occurred at 4,200 m, these findings are preliminary; finer-grained altitude sampling and larger samples are needed to identify critical altitude thresholds.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnins.2026.1719666","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:41:31Z","timestamp":1773124891000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of chronic high-altitude exposure on memory function in indigenous highland junior high school students: behavioral and electroencephalographic evidence"],"prefix":"10.3389","volume":"20","author":[{"given":"Xintong","family":"Chen","sequence":"first","affiliation":[{"name":"School of Education, Qinghai Normal University, Xining","place":["Qinghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weigang","family":"Gong","sequence":"additional","affiliation":[{"name":"School of Education, Qinghai Normal University, Xining","place":["Qinghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Lyu","sequence":"additional","affiliation":[{"name":"School of Nursing, Qingdao University","place":["Qingdao, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huiju","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine, Bijie Medical College, Bijie","place":["Guizhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[{"name":"School of Education, Qinghai Normal University, Xining","place":["Qinghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Education, Qinghai Normal University, Xining","place":["Qinghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Education, Qinghai Minzu University, Xining","place":["Qinghai, China"]},{"name":"Qinghai Plateau Brain Science Research Center, Xining","place":["Qinghai, China"]},{"name":"Qinghai Cardio-Cerebrovascular Specialty Hospital, Qinghai High Altitude Medical Research Institute, Xining","place":["Qinghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Fu","sequence":"additional","affiliation":[{"name":"School of Education, Qinghai Normal University, Xining","place":["Qinghai, China"]},{"name":"Qinghai Plateau Brain Science Research Center, Xining","place":["Qinghai, China"]},{"name":"Qinghai Cardio-Cerebrovascular Specialty Hospital, Qinghai High Altitude Medical Research Institute, Xining","place":["Qinghai, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"B1","first-page":"409","article-title":"Investigation of memory during adaptation to high mountain conditions.","volume":"7","author":"Bakharev","year":"1981","journal-title":"Hum. 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