{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T12:34:26Z","timestamp":1770813266906,"version":"3.50.1"},"reference-count":85,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Residual inhibition (RI) is clinically useful but lacks objective markers. Tailor-made notched music training (TMNMT) is a non-invasive paradigm that may elicit RI. We evaluated whether resting-state EEG spectral power ratios (SPR) provide a convergent electrophysiological signature of TMNMT-induced RI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed 29 adults with chronic subjective tinnitus who underwent a single 10-min TMNMT session. Resting-state EEG was recorded immediately before (pre-stim), during (during-stim), and after stimulation (post-stim). Power was estimated by Welch\u2019s method and summarized as band-limited SPR for delta (1\u20134\u202fHz), theta (4\u20138\u202fHz), alpha (8\u201313\u202fHz), and beta (13\u201330\u202fHz) relative to broadband power (1\u201330\u202fHz). Behavioral outcomes included visual analogue scales (VAS) for loudness\/annoyance and RI intensity and duration. Repeated-measures non-parametric tests with false-discovery-rate (FDR) correction were the primary analyses; effect sizes were reported where applicable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>RI was observed in 20 of 29 patients (69%) following the routine TMNMT exposure. Across the cohort, VAS loudness\/annoyance decreased within-session. SPR showed a frequency-specific shift characterized by increases in delta and theta power ratios and a reduction in alpha, with a non-significant downward trend in beta. Exploratory analyses suggested that higher baseline tinnitus severity (THI) was associated with greater VAS improvement and higher likelihood of RI positivity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present retrospective analysis characterized behavioral and EEG spectral patterns observed during routine TMNMT exposure. We observed that TMNMT produced measurable tinnitus relief accompanied by frequency-specific SPR shifts. These findings collectively offer preliminary observational evidence and practical rationale for the potential clinical utility of TMNMT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnins.2026.1732336","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T07:08:40Z","timestamp":1770793720000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Tailor-made notched music training\u2013induced residual inhibition in subjective tinnitus: resting-state EEG spectral power ratio evidence"],"prefix":"10.3389","volume":"20","author":[{"given":"Jiaqing","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital","place":["Tianjin, China"]},{"name":"Institute of Otolaryngology of Tianjin","place":["Tianjin, China"]},{"name":"Key Laboratory of Auditory Speech and Balance Medicine","place":["Tianjin, China"]},{"name":"Key Medical Discipline of Tianjin (Otolaryngology)","place":["Tianjin, China"]},{"name":"Quality Control Centre of Otolaryngology","place":["Tianjin, China"]},{"name":"First Central Clinical College, Tianjin Medical University","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital","place":["Tianjin, China"]},{"name":"Institute of Otolaryngology of Tianjin","place":["Tianjin, China"]},{"name":"Key Laboratory of Auditory Speech and Balance Medicine","place":["Tianjin, China"]},{"name":"Key Medical Discipline of Tianjin (Otolaryngology)","place":["Tianjin, China"]},{"name":"Quality Control Centre of Otolaryngology","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital","place":["Tianjin, China"]},{"name":"Institute of Otolaryngology of Tianjin","place":["Tianjin, China"]},{"name":"Key Laboratory of Auditory Speech and Balance Medicine","place":["Tianjin, China"]},{"name":"Key Medical Discipline of Tianjin (Otolaryngology)","place":["Tianjin, China"]},{"name":"Quality Control Centre of Otolaryngology","place":["Tianjin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1002\/hbm.22314","article-title":"Reversing pathologically increased EEG power by acoustic coordinated reset neuromodulation","volume":"35","author":"Adamchic","year":"2014","journal-title":"Hum. 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