{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T07:02:19Z","timestamp":1779778939741,"version":"3.53.1"},"reference-count":93,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS116418"],"award-info":[{"award-number":["NS116418"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS136246"],"award-info":[{"award-number":["NS136246"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurosci."],"abstract":"<jats:p>Mammalian neocortical development follows a precise spatiotemporal sequence to generate the organized structure responsible for higher-order cognition and behavior. Increasing evidence suggests that diversification of neural stem and progenitor cells during prenatal development is a key step in the emergence of the intricate circuitry and functional architecture of the cerebral cortex. This review discusses novel findings with an emphasis on mechanisms and consequences of cell lineage variation during normal and altered brain development, including focus on neurodevelopmental disorders such as autism spectrum disorders and Down syndrome.<\/jats:p>","DOI":"10.3389\/fnins.2026.1834625","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T06:03:46Z","timestamp":1779775426000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Progenitor diversity during formation of the mammalian neocortex"],"prefix":"10.3389","volume":"20","author":[{"given":"Zeynep","family":"Atak","sequence":"first","affiliation":[{"name":"Department of Anatomy and Neurobiology, Boston University School of Medicine","place":["Boston, MA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarik F.","family":"Haydar","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Neurobiology, Boston University School of Medicine","place":["Boston, MA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"9","DOI":"10.7554\/eLife.58737","article-title":"mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex","volume":"9","author":"Andrews","year":"2020","journal-title":"eLife"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e0040252025","DOI":"10.1523\/JNEUROSCI.0040-25.2025","article-title":"Disrupted Neurogenesis from Basal Intermediate Precursor Cells Alters the Postnatal Neocortex in the TcMAC21 Mouse Model of Down Syndrome","volume":"45","author":"Atak","year":"2025","journal-title":"J. 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