{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T06:25:07Z","timestamp":1787984707893,"version":"build-2784847793"},"reference-count":93,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T00:00:00Z","timestamp":1580774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Mol. Neurosci."],"DOI":"10.3389\/fnmol.2020.00003","type":"journal-article","created":{"date-parts":[[2020,2,4]],"date-time":"2020-02-04T01:14:57Z","timestamp":1580778897000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":29,"title":["Fibrogenesis in LAMA2-Related Muscular Dystrophy Is a Central Tenet of Disease Etiology"],"prefix":"10.3389","volume":"13","author":[{"given":"Anthony","family":"Accorsi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan L.","family":"Cramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahasweta","family":"Girgenrath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,2,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1159\/000452522","article-title":"Angiotensin-(1-7) prevents skeletal muscle atrophy induced by transforming growth factor type beta (TGF-\u03b2) via mas receptor activation.","volume":"40","author":"Abrigo","year":"2016","journal-title":"Cell. Physiol. Biochem."},{"key":"B2","doi-asserted-by":"publisher","first-page":"4624","DOI":"10.1093\/hmg\/ddw291","article-title":"IGF-1\/GH axis enhances losartan treatment in Lama2-related muscular dystrophy.","volume":"25","author":"Accorsi","year":"2016","journal-title":"Hum. Mol. Genet."},{"key":"B3","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3233\/jnd-140042","article-title":"Integrin dysregulation as a possible driver of matrix remodeling in Laminin-deficient congenital muscular dystrophy (MDC1A).","volume":"2","author":"Accorsi","year":"2015","journal-title":"J. Neuromuscul. Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1093\/hmg\/ddt514","article-title":"Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-beta signalling.","volume":"23","author":"Acuna","year":"2014","journal-title":"Hum. Mol. Genet."},{"key":"B5","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1038\/sj.ejhg.5200743","article-title":"Merosin-deficient congenital muscular dystrophy, autosomal recessive (MDC1A, MIM#156225, LAMA2 gene coding for alpha2 chain of laminin).","volume":"10","author":"Allamand","year":"2002","journal-title":"Eur. J. Hum. Genet."},{"key":"B6","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1242\/jcs.00229","article-title":"Making sense of latent TGFbeta activation.","author":"Annes","year":"2003","journal-title":"J. Cell Sci."},{"key":"B7","doi-asserted-by":"publisher","first-page":"9","DOI":"10.18553\/jmcp.2007.13.s8-b.9","article-title":"The renin-angiotensin aldosterone system: pathophysiological role and pharmacologic inhibition.","volume":"13","author":"Atlas","year":"2007","journal-title":"J. Manag. Care Pharm."},{"key":"B8","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.pcad.2016.10.002","article-title":"Renin angiotensin aldosterone system inhibitors in hypertension: is there evidence for benefit independent of blood pressure reduction?","volume":"59","author":"Bavishi","year":"2016","journal-title":"Prog. Cardiovasc. Dis."},{"key":"B9","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.spen.2011.10.010","article-title":"Congenital muscular dystrophies: a brief review.","volume":"18","author":"Bertini","year":"2011","journal-title":"Semin. Pediatr. Neurol."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0218683","article-title":"On behalf on the international, long-term natural history data in Duchenne muscular dystrophy ambulant patients with mutations amenable to skip exons 44, 45, 51 and 53.","volume":"14","author":"Brogna","year":"2019","journal-title":"PLoS One"},{"key":"B11","doi-asserted-by":"publisher","first-page":"560","DOI":"10.2174\/138920312803582933","article-title":"Angiotensin II: role in skeletal muscle atrophy.","volume":"13","author":"Cabello-Verrugio","year":"2012","journal-title":"Curr. Protein Pept. Sci."},{"key":"B12","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1083\/jcb.201510086","article-title":"Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype.","volume":"213","author":"Capote","year":"2016","journal-title":"J. Cell Biol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1038\/ki.2008.213","article-title":"Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation.","volume":"74","author":"Carvajal","year":"2008","journal-title":"Kidney Int."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1091\/mbc.E09-09-0812","article-title":"Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1\/S1P3 axis.","volume":"21","author":"Cencetti","year":"2010","journal-title":"Mol. Biol. Cell"},{"key":"B15","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1038\/nm1536","article-title":"Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.","volume":"13","author":"Cohn","year":"2007","journal-title":"Nat. Med."},{"key":"B16","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s11910-010-0092-8","article-title":"Congenital muscular dystrophies: toward molecular therapeutic interventions.","volume":"10","author":"Collins","year":"2010","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"B17","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1007\/s00441-016-2407-9","article-title":"\u03b1v integrins: key regulators of tissue fibrosis.","volume":"365","author":"Conroy","year":"2016","journal-title":"Cell Tissue Res."},{"key":"B18","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s00441-015-2343-0","article-title":"Connective tissue cells expressing fibro\/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis.","volume":"364","author":"Contreras","year":"2016","journal-title":"Cell Tissue Res."},{"key":"B19","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1002\/ana.22694","article-title":"Losartan, a therapeutic candidate in congenital muscular dystrophy: studies in the dy(2J)\/dy(2J) mouse.","volume":"71","author":"Elbaz","year":"2012","journal-title":"Ann. Neurol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1083\/jcb.200405004","article-title":"Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments.","volume":"166","author":"Engler","year":"2004","journal-title":"J. Cell Biol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1124\/jpet.109.160754","article-title":"Omigapil ameliorates the pathology of muscle dystrophy caused by laminin-alpha2 deficiency.","volume":"331","author":"Erb","year":"2009","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"B22","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/s0895-7061(99)00152-1","article-title":"Angiotensin II upregulates transforming growth factor-beta type I receptor on rat vascular smooth muscle cells.","volume":"13","author":"Fukuda","year":"2000","journal-title":"Am. J. Hypertens."},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1186\/2044-5040-1-9","article-title":"Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies.","volume":"1","author":"Gawlik","year":"2011","journal-title":"Skelet. Muscle"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/srep44059","article-title":"Potent pro-inflammatory and pro-fibrotic molecules, osteopontin and galectin-3, are not major disease modulators of laminin alpha2 chain-deficient muscular dystrophy.","volume":"7","author":"Gawlik","year":"2017","journal-title":"Sci. Rep."},{"key":"B25","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.nmd.2010.02.001","article-title":"Genotype-phenotype correlation in a large population of muscular dystrophy patients with LAMA2 mutations.","volume":"20","author":"Geranmayeh","year":"2010","journal-title":"Neuromuscul. Disord."},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/210797","article-title":"The dystrophin-glycoprotein complex in the prevention of muscle damage.","volume":"2011","author":"Gumerson","year":"2011","journal-title":"J Biomed. Biotechnol."},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0173557","article-title":"Non-invasive evaluation of muscle disease in the canine model of Duchenne muscular dystrophy by electrical impedance myography.","volume":"12","author":"Hakim","year":"2017","journal-title":"PLoS One"},{"key":"B28","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1038\/sj.jid.5700613","article-title":"Formation and function of the myofibroblast during tissue repair.","volume":"127","author":"Hinz","year":"2007","journal-title":"J. Invest. Dermatol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.jbiomech.2009.09.020","article-title":"The myofibroblast: paradigm for a mechanically active cell.","volume":"43","author":"Hinz","year":"2010","journal-title":"J. Biomech."},{"key":"B30","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.matbio.2015.05.006","article-title":"The extracellular matrix and transforming growth factor-beta1: tale of a strained relationship.","volume":"47","author":"Hinz","year":"2015","journal-title":"Matrix Biol."},{"key":"B31","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.2353\/ajpath.2007.070112","article-title":"The myofibroblast: one function, multiple origins.","volume":"170","author":"Hinz","year":"2007","journal-title":"Am. J. Pathol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"111","DOI":"10.4161\/cam.22618","article-title":"Laminin-211 in skeletal muscle function.","volume":"7","author":"Holmberg","year":"2013","journal-title":"Cell Adh. Migr."},{"key":"B33","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1016\/S0021-9258(17)35666-1","article-title":"Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.","volume":"261","author":"Ignotz","year":"1986","journal-title":"J. Biol. Chem."},{"key":"B34","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1007\/s00018-004-4510-4","article-title":"Congenital muscular dystrophy: molecular and cellular aspects.","volume":"62","author":"Jimenez-Mallebrera","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"86447","DOI":"10.18632\/oncotarget.21200","article-title":"Halofuginone inhibits TGF-beta\/BMP signaling and in combination with zoledronic acid enhances inhibition of breast cancer bone metastasis.","volume":"8","author":"Juarez","year":"2017","journal-title":"Oncotarget"},{"key":"B36","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1161\/01.hyp.35.1.273","article-title":"Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts.","volume":"35","author":"Kawano","year":"2000","journal-title":"Hypertension"},{"key":"B37","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1038\/s41586-019-1430-x","article-title":"A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene.","volume":"572","author":"Kemaladewi","year":"2019","journal-title":"Nature"},{"key":"B38","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1002\/path.4104","article-title":"The myofibroblast matrix: implications for tissue repair and fibrosis.","volume":"229","author":"Klingberg","year":"2013","journal-title":"J. Pathol."},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00470","article-title":"Identification of candidate protein markers in skeletal muscle of laminin-211-deficient CMD type 1A-patients.","volume":"10","author":"Kolbel","year":"2019","journal-title":"Front. Neurol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1161\/01.res.0000126574.61061.25","article-title":"The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma.","volume":"94","author":"Lapidos","year":"2004","journal-title":"Circ. Res."},{"key":"B41","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-018-0455-7","article-title":"Robust inflammatory and fibrotic signaling following volumetric muscle loss: a barrier to muscle regeneration.","volume":"9","author":"Larouche","year":"2018","journal-title":"Cell Death Dis."},{"key":"B42","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1096\/fj.03-1273rev","article-title":"TGF-beta signaling and the fibrotic response.","volume":"18","author":"Leask","year":"2004","journal-title":"FASEB J."},{"key":"B43","first-page":"426","article-title":"Distribution of merosin, a laminin-related tissue-specific basement membrane protein, in human Schwann cell neoplasms.","volume":"61","author":"Leivo","year":"1989","journal-title":"Lab. Invest."},{"key":"B44","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1038\/nm.3869","article-title":"Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro\/adipogenic progenitors.","volume":"21","author":"Lemos","year":"2015","journal-title":"Nat. Med."},{"key":"B45","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.bbadis.2006.09.006","article-title":"Congenital muscular dystrophies: new aspects of an expanding group of disorders.","volume":"1772","author":"Lisi","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"B46","doi-asserted-by":"publisher","first-page":"10978","DOI":"10.1073\/pnas.1204708109","article-title":"Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-beta pathway.","volume":"109","author":"Lorts","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B47","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1111\/j.1582-4934.2011.01419.x","article-title":"\u03b1v integrins and TGF-beta-induced EMT: a circle of regulation.","volume":"16","author":"Mamuya","year":"2012","journal-title":"J. Cell. Mol. Med."},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20130068","article-title":"Twist reverses muscle cell differentiation through transcriptional down-regulation of myogenin.","volume":"33","author":"Mastroyiannopoulos","year":"2013","journal-title":"Biosci. Rep."},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1186\/2044-5040-4-14","article-title":"Dysregulation of matricellular proteins is an early signature of pathology in laminin-deficient muscular dystrophy.","volume":"4","author":"Mehuron","year":"2014","journal-title":"Skelet. Muscle"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1186\/2044-5040-2-18","article-title":"Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A).","volume":"2","author":"Meinen","year":"2012","journal-title":"Skelet. Muscle"},{"key":"B51","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1038\/35095054","article-title":"An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.","volume":"413","author":"Moll","year":"2001","journal-title":"Nature"},{"key":"B52","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1242\/dmm.023390","article-title":"Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas.","volume":"9","author":"Morales","year":"2016","journal-title":"Dis. Model. Mech."},{"key":"B53","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1002\/mus.26127","article-title":"Electrical impedance myography in facioscapulohumeral muscular dystrophy: a 1-year follow-up study.","volume":"58","author":"Mul","year":"2018","journal-title":"Muscle Nerve"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a005017","article-title":"Cross talk among TGF-beta signaling pathways, integrins, and the extracellular matrix.","volume":"3","author":"Munger","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01097-z","article-title":"\u03b1v integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis.","volume":"8","author":"Murray","year":"2017","journal-title":"Nat. Commun."},{"key":"B56","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1002\/glia.1075","article-title":"Schwann cell myelination occurred without basal lamina formation in laminin alpha2 chain-null mutant (dy3K\/dy3K) mice.","volume":"35","author":"Nakagawa","year":"2001","journal-title":"Glia"},{"key":"B57","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1002\/mus.21706","article-title":"Fibrosis inhibition and muscle histopathology improvement in laminin-alpha2-deficient mice.","volume":"42","author":"Nevo","year":"2010","journal-title":"Muscle Nerve"},{"key":"B58","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1002\/mus.25629","article-title":"Electrical impedance myography in individuals with collagen 6 and laminin alpha-2 congenital muscular dystrophy: a cross-sectional and 2-year analysis.","volume":"57","author":"Nichols","year":"2018","journal-title":"Muscle Nerve"},{"key":"B59","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1083\/jcb.139.6.1507","article-title":"Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.","volume":"139","author":"Patton","year":"1997","journal-title":"J. Cell Biol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1016\/j.stemcr.2015.04.007","article-title":"Fibrogenic cell plasticity blunts tissue regeneration and aggravates muscular dystrophy.","volume":"4","author":"Pessina","year":"2015","journal-title":"Stem Cell Reports"},{"key":"B61","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1136\/adc.80.6.542","article-title":"Feeding problems in merosin deficient congenital muscular dystrophy.","volume":"80","author":"Philpot","year":"1999","journal-title":"Arch. Dis. Child."},{"key":"B62","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/j.bbadis.2009.06.004","article-title":"TGF-beta and fibrosis in different organs \u2013 molecular pathway imprints.","volume":"1792","author":"Pohlers","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"B63","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1038\/mt.2008.239","article-title":"Gene-mediated restoration of normal myofiber elasticity in dystrophic muscles.","volume":"17","author":"Puttini","year":"2009","journal-title":"Mol. Ther."},{"key":"B64","article-title":"LAMA2-related muscular dystrophy","author":"Quijano-Roy","year":"1993","journal-title":"GeneReviews<sup>\u00ae<\/sup>"},{"key":"B65","doi-asserted-by":"publisher","first-page":"2509","DOI":"10.1161\/01.cir.0000165133.84978.e2","article-title":"Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism.","volume":"111","author":"Rodriguez-Vita","year":"2005","journal-title":"Circulation"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1088\/1468-6996\/13\/6\/064211","article-title":"Substrate stiffness affects skeletal myoblast differentiation in vitro.","volume":"13","author":"Romanazzo","year":"2012","journal-title":"Sci. Technol. Adv. Mater."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1016\/j.ajpath.2011.12.019","article-title":"Laminin-111 protein therapy reduces muscle pathology and improves viability of a mouse model of merosin-deficient congenital muscular dystrophy.","volume":"180","author":"Rooney","year":"2012","journal-title":"Am. J. Pathol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1002\/ana.24874","article-title":"Electrical impedance myography for assessment of Duchenne muscular dystrophy.","volume":"81","author":"Rutkove","year":"2017","journal-title":"Ann. Neurol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"2413","DOI":"10.1016\/j.clinph.2007.08.004","article-title":"Electrical impedance myography to assess outcome in amyotrophic lateral sclerosis clinical trials.","volume":"118","author":"Rutkove","year":"2007","journal-title":"Clin. Neurophysiol."},{"key":"B70","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1042\/CS20130602","article-title":"Chronic oral administration of Ang-(1-7) improves skeletal muscle, autonomic and locomotor phenotypes in muscular dystrophy.","volume":"127","author":"Sabharwal","year":"2014","journal-title":"Clin. Sci. (Lond.)"},{"key":"B71","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/s1359-6101(99)00010-6","article-title":"Latent transforming growth factor-beta binding proteins (LTBPs)\u2013structural extracellular matrix proteins for targeting TGF-beta action.","volume":"10","author":"Saharinen","year":"1999","journal-title":"Cytokine Growth Factor Rev."},{"key":"B72","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.spen.2006.06.003","article-title":"Congenital muscular dystrophies and the extracellular matrix.","volume":"13","author":"Schessl","year":"2006","journal-title":"Semin. Pediatr. Neurol."},{"key":"B73","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1083\/jcb.122.4.923","article-title":"Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism.","volume":"122","author":"Schultz-Cherry","year":"1993","journal-title":"J. Cell Biol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1016\/s0092-8674(03)00432-x","article-title":"Mechanisms of TGF-beta signaling from cell membrane to the nucleus.","volume":"113","author":"Shi","year":"2003","journal-title":"Cell"},{"key":"B75","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1042\/BC20070115","article-title":"Alpha v beta 3 and alpha v beta 5 integrins and their role in muscle precursor cell adhesion.","volume":"100","author":"Sinanan","year":"2008","journal-title":"Biol. Cell"},{"key":"B76","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.molcel.2012.05.046","article-title":"Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis.","volume":"47","author":"Soleimani","year":"2012","journal-title":"Mol. Cell"},{"key":"B77","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1002\/cphy.c130040","article-title":"Classical Renin-Angiotensin system in kidney physiology.","volume":"4","author":"Sparks","year":"2014","journal-title":"Compr. Physiol."},{"key":"B78","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1083\/jcb.139.2.375","article-title":"Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.","volume":"139","author":"Straub","year":"1997","journal-title":"J. Cell Biol."},{"key":"B79","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1097\/00005344-199900001-00005","article-title":"The renin-angiotensin system and its receptors.","volume":"33","author":"Stroth","year":"1999","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"B80","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jns.2009.01.020","article-title":"Intramuscular renin-angiotensin system is activated in human muscular dystrophy.","volume":"280","author":"Sun","year":"2009","journal-title":"J. Neurol. Sci."},{"key":"B81","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1093\/emboj\/18.4.863","article-title":"Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.","volume":"18","author":"Talts","year":"1999","journal-title":"EMBO J."},{"key":"B82","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.bbrc.2005.12.224","article-title":"Expression profiling of muscles from Fukuyama-type congenital muscular dystrophy and laminin-alpha 2 deficient congenital muscular dystrophy; is congenital muscular dystrophy a primary fibrotic disease?","volume":"342","author":"Taniguchi","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B83","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1002\/humu.10157","article-title":"Clinical and molecular study in congenital muscular dystrophy with partial laminin alpha 2 (LAMA2) deficiency.","volume":"21","author":"Tezak","year":"2003","journal-title":"Hum. Mutat."},{"key":"B84","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/03008207.2014.947369","article-title":"Extracellular matrix regulation in the muscle satellite cell niche.","volume":"56","author":"Thomas","year":"2015","journal-title":"Connect. Tissue Res."},{"key":"B85","first-page":"351","article-title":"Congenital muscular dystrophy with merosin deficiency.","volume":"317","author":"Tome","year":"1994","journal-title":"C. R. Acad. Sci. III"},{"key":"B86","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.biocel.2007.07.015","article-title":"Bridging structure with function: structural, regulatory, and developmental role of laminins.","volume":"40","author":"Tzu","year":"2008","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0138254","article-title":"Magnetic resonance imaging is sensitive to pathological amelioration in a model for laminin-deficient congenital muscular dystrophy (MDC1A).","volume":"10","author":"Vohra","year":"2015","journal-title":"PLoS One"},{"key":"B88","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.tibs.2010.08.002","article-title":"TGFbeta: a sleeping giant awoken by integrins.","volume":"36","author":"Worthington","year":"2011","journal-title":"Trends Biochem. Sci."},{"key":"B89","doi-asserted-by":"publisher","first-page":"4306","DOI":"10.1093\/hmg\/ddt280","article-title":"Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A.","volume":"22","author":"Yamauchi","year":"2013","journal-title":"Hum. Mol. Genet."},{"key":"B90","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/0076-6879(94)45025-0","article-title":"Basement membrane assembly.","volume":"245","author":"Yurchenco","year":"1994","journal-title":"Methods Enzymol."},{"key":"B91","doi-asserted-by":"publisher","first-page":"30091","DOI":"10.1074\/jbc.m202668200","article-title":"Slug is a novel downstream target of MyoD.","volume":"277","author":"Zhao","year":"2002","journal-title":"J. Biol. Chem."},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12996","article-title":"Elevated H3K27ac in aged skeletal muscle leads to increase in extracellular matrix and fibrogenic conversion of muscle satellite cells.","volume":"18","author":"Zhou","year":"2019","journal-title":"Aging Cell"},{"key":"B93","doi-asserted-by":"publisher","first-page":"4496","DOI":"10.1016\/j.bmc.2009.05.011","article-title":"Synthesis and biological evaluation of febrifugine analogues as potential antimalarial agents.","volume":"17","author":"Zhu","year":"2009","journal-title":"Bioorg. Med. Chem."}],"container-title":["Frontiers in Molecular Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnmol.2020.00003\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T15:44:52Z","timestamp":1614267892000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnmol.2020.00003\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,4]]},"references-count":93,"alternative-id":["10.3389\/fnmol.2020.00003"],"URL":"https:\/\/doi.org\/10.3389\/fnmol.2020.00003","relation":{},"ISSN":["1662-5099"],"issn-type":[{"value":"1662-5099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,4]]},"article-number":"3"}}