{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:22:29Z","timestamp":1790785349912,"version":"4.1.0"},"reference-count":37,"publisher":"Frontiers Media SA","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Syst. Neurosci."],"DOI":"10.3389\/fnsys.2014.00241","type":"journal-article","created":{"date-parts":[[2015,1,7]],"date-time":"2015-01-07T08:30:13Z","timestamp":1420619413000},"source":"Crossref","is-referenced-by-count":37,"title":["Upper esophageal sphincter mechanical states analysis: a novel methodology to describe UES relaxation and opening"],"prefix":"10.3389","volume":"8","author":[{"given":"Taher I.","family":"Omari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukasz","family":"Wiklendt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Dinning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Rommel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Cock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2015,1,7]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1472-684X-4-7","article-title":"The Australia-modified Karnofsky Performance Status (AKPS) scale: a revised scale for contemporary palliative care clinical practice [ISRCTN81117481]","volume":"4","author":"Abernethy","year":"2005","journal-title":"BMC Palliat. Care"},{"key":"B2","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/PL00009527","article-title":"Predictors of outcome following cricopharyngeal disruption for pharyngeal dysphagia","volume":"12","author":"Ali","year":"1997","journal-title":"Dysphagia"},{"key":"B3","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/0016-5085(78)90288-3","article-title":"Manometry and electromyography of the upper esophageal sphincter in the opossum","volume":"74","author":"Asoh","year":"1978","journal-title":"Gastroenterology"},{"key":"B4","doi-asserted-by":"publisher","first-page":"99","DOI":"10.5056\/jnm.2013.19.1.99","article-title":"How to perform and interpret upper esophageal sphincter manometry","volume":"19","author":"Bhatia","year":"2013","journal-title":"J. Neurogastroenterol. Motil"},{"key":"B5","doi-asserted-by":"publisher","first-page":"2521","DOI":"10.1002\/lary.22365","article-title":"Efficacy of large-diameter dilatation in cricopharyngeal dysfunction","volume":"121","author":"Clary","year":"2011","journal-title":"Laryngoscope"},{"key":"B6","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.gtc.2009.06.003","article-title":"Oropharyngeal dysphagia","volume":"38","author":"Cook","year":"2009","journal-title":"Gastroenterol. Clin. North Am"},{"key":"B7","first-page":"G748","article-title":"Opening mechanisms of the human upper esophageal sphincter","volume":"257","author":"Cook","year":"1989","journal-title":"Am. J. Physiol"},{"issue":"7","key":"B8","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2013.00007","article-title":"An experimental method to identify neurogenic and myogenic active mechanical states of intestinal motility","volume":"7","author":"Costa","year":"2013","journal-title":"Front. Syst. Neurosci"},{"issue":"75","key":"B9","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2014.00075","article-title":"Neural mechanisms of peristalsis in the isolated rabbit distal colon: a neuromechanical loop hypothesis","volume":"8","author":"Dinning","year":"2014","journal-title":"Front. Neurosci"},{"key":"B10","doi-asserted-by":"crossref","first-page":"349","DOI":"10.5935\/1808-8694.20130061","article-title":"Fiberoptic endoscopy evaluation of swallowing in patients with amyotrophic lateral sclerosis","volume":"79","author":"D'Ottaviano","year":"2013","journal-title":"Braz. J. Otorhinolaryngol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1093\/brain\/123.1.125","article-title":"Pathophysiological mechanisms of oropharyngeal dysphagia in amyotrophic lateral sclerosis","volume":"123(Pt 1)","author":"Ertekin","year":"2000","journal-title":"Brain"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1002\/mus.880181014","article-title":"An electrophysiological investigation of deglutition in man","volume":"18","author":"Ertekin","year":"1995","journal-title":"Muscle Nerve"},{"key":"B13","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1007\/s00455-006-9052-5","article-title":"Assessment of swallowing by oropharyngoesophageal scintigraphy in patients with amyotrophic lateral sclerosis","volume":"21","author":"Fattori","year":"2006","journal-title":"Dysphagia"},{"key":"B14","doi-asserted-by":"publisher","first-page":"G525","DOI":"10.1152\/ajpgi.00081.2006","article-title":"Deglutitive upper esophageal sphincter relaxation: a study of 75 volunteer subjects using solid-state high-resolution manometry","volume":"291","author":"Ghosh","year":"2006","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"B15","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/dote\/11.4.254","article-title":"Dilatation therapy for dysphagia in patients with upper esophageal dysfunction\u00e2\u20ac\u201dmanometric and symptomatic response","volume":"11","author":"Hatlebakk","year":"1998","journal-title":"Dis. Esophagus"},{"key":"B16","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.anl.2004.05.009","article-title":"Longitudinal analysis of progression of dysphagia in amyotrophic lateral sclerosis","volume":"31","author":"Higo","year":"2004","journal-title":"Auris Nasus Larynx"},{"key":"B17","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1097\/00004836-200111000-00003","article-title":"Pharyngeal and upper esophageal sphincter manometry in the evaluation of dysphagia","volume":"33","author":"Hila","year":"2001","journal-title":"J. Clin. Gastroenterol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1177\/0003489414522975","article-title":"Quantifying contributions of the cricopharyngeus to upper esophageal sphincter pressure changes by means of intramuscular electromyography and high-resolution manometry","volume":"123","author":"Jones","year":"2014","journal-title":"Ann. Otol. Rhinol. Laryngol"},{"key":"B19","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/0016-5085(88)90290-9","article-title":"Upper esophageal sphincter function during degluition","volume":"95","author":"Kahrilas","year":"1988","journal-title":"Gastroenterology"},{"key":"B20","first-page":"G450","article-title":"Volitional augmentation of upper esophageal sphincter opening during swallowing","volume":"260","author":"Kahrilas","year":"1991","journal-title":"Am. J. Physiol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1177\/000348941312200205","article-title":"Botulinum toxin injection for the treatment of upper esophageal sphincter dysfunction","volume":"122","author":"Kelly","year":"2013","journal-title":"Ann. Otol. Rhinol. Laryngol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"43S","DOI":"10.1016\/S0002-9343(99)00334-4","article-title":"Management of upper esophageal sphincter disorders: indications and complications of myotomy","volume":"108","author":"Kelly","year":"2000","journal-title":"Am. J. Med"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1111\/nmo.12369","article-title":"Esophageal distension during bolus transport: can it be detected by intraluminal impedance recordings?","volume":"26","author":"Kim","year":"2014","journal-title":"Neurogastroenterol. Motil"},{"key":"B24","doi-asserted-by":"publisher","first-page":"e821","DOI":"10.1111\/nmo.12209","article-title":"Biomechanical changes in the pharynx and upper esophageal sphincter after modified balloon dilatation in brainstem stroke patients with dysphagia","volume":"25","author":"Lan","year":"2013","journal-title":"Neurogastroenterol. Motil"},{"key":"B25","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1152\/ajpgi.1991.260.6.G911","article-title":"Analysis of canine upper esophageal sphincter","volume":"260","author":"Lang","year":"1991","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1288\/00005537-196501000-00014","article-title":"The cricopharyngeus muscle, an electromygraphic study in the dog","volume":"75","author":"Levitt","year":"1965","journal-title":"Laryngoscope"},{"key":"B27","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1097\/00000658-199810000-00016","article-title":"Pharyngeal swallowing disorders: selection for and outcome after myotomy","volume":"228","author":"Mason","year":"1998","journal-title":"Ann. Surg"},{"key":"B28","doi-asserted-by":"crossref","first-page":"G470","DOI":"10.1152\/ajpgi.1997.273.2.G470","article-title":"Correlation of electrical of the cricopharyngeus and contractile activities muscle in the cat","volume":"273","author":"Medda","year":"1997","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"G909","DOI":"10.1152\/ajpgi.00473.2011","article-title":"Upper esophageal sphincter impedance as a marker of sphincter opening diameter","volume":"302","author":"Omari","year":"2012","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"G1037","DOI":"10.1152\/ajpgi.00030.2003","article-title":"Intrabolus pressure gradient identifies pathological constriction in the upper esophageal sphincter during flow","volume":"285","author":"Pal","year":"2003","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1053\/gast.2002.32999","article-title":"Rehabilitation of swallowing by exercise in tube-fed patients with pharyngeal dysphagia secondary to abnormal UES opening","volume":"122","author":"Shaker","year":"2002","journal-title":"Gastroenterology"},{"key":"B32","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1152\/ajpgi.1997.272.6.G1518","article-title":"Augmentation of deglutitive upper esophageal sphincter opening in the elderly by excercise","volume":"35","author":"Shaker","year":"1997","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"B33","first-page":"G389","article-title":"Influence of normal aging on oral-pharyngeal and upper esophageal sphincter function during swallowing","volume":"268","author":"Shaw","year":"1995","journal-title":"Am. J. Physiol"},{"key":"B34","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1288\/00005537-198505000-00011","article-title":"Simultaneous manometry and electromyography in the pharyngoesophageal segment","volume":"95","author":"Van Overbeek","year":"1985","journal-title":"Laryngoscope"},{"key":"B35","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1111\/nmo.12314","article-title":"Normal values for solid-state esophageal high-resolution manometry in a European population; an overview of all current metrics","volume":"26","author":"Weijenborg","year":"2014","journal-title":"Neurogastroenterol. Motil"},{"key":"B36","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1472-6793-13-14","article-title":"Inference of mechanical states of intestinal motor activity using hidden Markov models","volume":"13","author":"Wiklendt","year":"2013","journal-title":"BMC Physiol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"G16","DOI":"10.1152\/ajpgi.00189.2001","article-title":"Biomechanics of failed deglutitive upper esophageal sphincter relaxation in neurogenic dysphagia","volume":"283","author":"Williams","year":"2002","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"}],"container-title":["Frontiers in Systems Neuroscience"],"original-title":[],"deposited":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T06:37:13Z","timestamp":1566196633000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fnsys.2014.00241\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,7]]},"references-count":37,"URL":"https:\/\/doi.org\/10.3389\/fnsys.2014.00241","relation":{},"ISSN":["1662-5137"],"issn-type":[{"value":"1662-5137","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,7]]}}}