{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:57:15Z","timestamp":1792043835229,"version":"4.4.0"},"reference-count":75,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Syst. Neurosci."],"DOI":"10.3389\/fnsys.2015.00158","type":"journal-article","created":{"date-parts":[[2015,11,16]],"date-time":"2015-11-16T06:03:00Z","timestamp":1447653780000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":33,"title":["Impaired Processing in the Primary Auditory Cortex of an Animal Model of Autism"],"prefix":"10.3389","volume":"9","author":[{"given":"Renata Figueiredo","family":"Anomal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"de Villers-Sidani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Alves","family":"Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Diniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos R.","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo N.","family":"Romcy-Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2015,11,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"163","DOI":"10.3389\/fncel.2014.00163","article-title":"Altered GABAergic markers, increased binocularity and reduced plasticity in the visual cortex of Engrailed-2 knockout mice","volume":"8","author":"Allegra","year":"2014","journal-title":"Front. Cell Neurosci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e64208","DOI":"10.1371\/journal.pone.0064208","article-title":"Manipulation of BDNF signaling modifies the experience-dependent plasticity induced by pure tone exposure during the critical period in the primary auditory cortex","volume":"8","author":"Anomal","year":"2013","journal-title":"PLoS One"},{"key":"B3","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.brainres.2011.06.015","article-title":"Animal model of autism induced by prenatal exposure to valproate: behavioral changes and liver parameters","volume":"1408","author":"Bambini-Junior","year":"2011","journal-title":"Brain Res."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1017\/s1461145712001216","article-title":"Impairment of cortical GABAergic synaptic transmission in an environmental rat model of autism","volume":"16","author":"Banerjee","year":"2013","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"B5","doi-asserted-by":"crossref","first-page":"10765","DOI":"10.1523\/JNEUROSCI.23-34-10765.2003","article-title":"Progressive degradation and subsequent refinement of acoustic representations in the adult auditory cortex","volume":"23","author":"Bao","year":"2003","journal-title":"J. Neurosci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1038\/nn1293","article-title":"Temporal plasticity in the primary auditory cortex induced by operant perceptual learning","volume":"7","author":"Bao","year":"2004","journal-title":"Nat. Neurosci."},{"key":"B8","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.yfrne.2013.07.006","article-title":"Estrogenic modulation of auditory processing: a vertebrate comparison","volume":"34","author":"Calas","year":"2013","journal-title":"Front. Neuroendocrinol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"16460","DOI":"10.1073\/pnas.0508239102","article-title":"Development of spectral and temporal response selectivity in the auditory cortex","volume":"102","author":"Chang","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"B10","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1126\/science.1082163","article-title":"Environmental noise retards auditory cortical development","volume":"300","author":"Chang","year":"2003","journal-title":"Science"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1001\/jama.2013.2270","article-title":"Prenatal valproate exposure and risk of autism spectrum disorders and childhood autism","volume":"309","author":"Christensen","year":"2013","journal-title":"JAMA"},{"key":"B12","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1469-8749.1994.tb11858.x","article-title":"Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs","volume":"36","author":"Christianson","year":"1994","journal-title":"Dev. Med. Child Neurol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"e484","DOI":"10.1038\/tp.2014.123","article-title":"Deletion of \u03b1-neurexin II results in autism-related behaviors in mice","volume":"4","author":"Dachtler","year":"2014","journal-title":"Transl. Psychiatry."},{"key":"B14","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s10803-005-0055-0","article-title":"Subjective perceptual distortions and visual dysfunction in children with autism","volume":"36","author":"Davis","year":"2006","journal-title":"J. Autism Dev. Disord."},{"key":"B15","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1523\/jneurosci.3227-06.2007","article-title":"Critical period window for spectral tuning defined in the primary auditory cortex (AI). in the rat","volume":"27","author":"de Villers-Sidani","year":"2007","journal-title":"J Neurosci."},{"key":"B16","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1038\/nn.2144","article-title":"Manipulating critical period closure across different sectors of the primary auditory cortex","volume":"11","author":"de Villers-Sidani","year":"2008","journal-title":"Nat. Neurosci."},{"key":"B17","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/0165-3806(94)90311-5","article-title":"The development of parvalbumin-immunoreactivity in the neocortex of the mouse","volume":"81","author":"del Rio","year":"1994","journal-title":"Brain Res. Dev."},{"key":"B18","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.brainres.2006.08.115","article-title":"Decreased expression of the GABAA receptor in fragile X syndrome","volume":"1121","author":"D\u2019Hulst","year":"2006","journal-title":"Brain Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1002\/cne.10412","article-title":"Redefining the tonotopic core of rat auditory cortex: physiological evidence for a posterior field","volume":"453","author":"Doron","year":"2002","journal-title":"J. Comp. Neurol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.brainres.2013.06.024","article-title":"Increased hippocampal cell density and enhanced spatial memory in the valproic acid rat model of autism","volume":"1526","author":"Edalatmanesh","year":"2013","journal-title":"Brain Res."},{"key":"B22","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1002\/dneu.22175","article-title":"Degraded auditory processing in a rat model of autism limits the speech representation in non-primary auditory cortex","volume":"74","author":"Engineer","year":"2014a","journal-title":"Dev. Neurobiol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.brainres.2014.03.049","article-title":"Degraded speech sound processing in a rat model of fragile X syndrome","volume":"1564","author":"Engineer","year":"2014b","journal-title":"Brain Res."},{"key":"B24","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.nbd.2015.08.019","article-title":"Degraded neural and behavioral processing of speech sounds in a rat model of Rett syndrome","volume":"83","author":"Engineer","year":"2015","journal-title":"Neurobiol. Dis."},{"key":"B25","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1038\/35004582","article-title":"Inhibitory threshold for critical-period activation in primary visual cortex","volume":"404","author":"Fangiolini","year":"2000","journal-title":"Nature"},{"key":"B26","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1038\/nn.3274","article-title":"Long-term modification of cortical synapses improves sensory perception","volume":"16","author":"Froemke","year":"2013","journal-title":"Nat. Neurosci."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.brainresrev.2006.09.006","article-title":"The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system","volume":"54","author":"Galtrey","year":"2007","journal-title":"Brain Res. Rev."},{"key":"B28","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1007\/s11689-009-9023-x","article-title":"Common circuit defect of excitatory-inhibitory balance in mouse models of autism","volume":"1","author":"Gogolla","year":"2009","journal-title":"J. Neurodev. Disord."},{"key":"B29","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1590\/S0104-56872008000400013","article-title":"Auditory hypersensitivity in the autistic spectrum disorder","volume":"20","author":"Gomes","year":"2008","journal-title":"Pro. Fono."},{"key":"B30","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.pediatrneurol.2009.10.009","article-title":"Childhood autism and auditory system abnormalities","volume":"42","author":"Hitoglou","year":"2010","journal-title":"Pediatr. Neurol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"S56","DOI":"10.1121\/1.2026374","article-title":"Tonotopic representation in the rat auditory cortex","volume":"84","author":"Horikawa","year":"1988","journal-title":"J. Acoust. Soc. Am."},{"key":"B32","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/s0092-8674(00)81509-3","article-title":"BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex","volume":"98","author":"Huang","year":"1999","journal-title":"Cell"},{"key":"B33","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1073\/pnas.0711555105","article-title":"Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism","volume":"105","author":"Jamain","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"B34","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1038\/mp.2012.105","article-title":"Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?","volume":"17","author":"Kapur","year":"2012","journal-title":"Mol. Psychiatry"},{"key":"B35","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1017\/s1461145711001714","article-title":"Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid","volume":"16","author":"Kataoka","year":"2013","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/s0378-5955(99)00061-1","article-title":"Distributed representation of spectral and temporal information in rat primary auditory cortex","volume":"134","author":"Kilgard","year":"1999","journal-title":"Hear. Res."},{"key":"B37","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1152\/jn.00230.2013","article-title":"Experience-dependent overrepresentation of ultrasonic vocalization frequencies in the rat primary auditory cortex","volume":"110","author":"Kim","year":"2013","journal-title":"J. Neurophysiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/bf01066416","article-title":"Auditory brainstem responses in autism: brainstem dysfunction or peripheral hearing loss?","volume":"23","author":"Klin","year":"1993","journal-title":"J. Autism. Dev. Disord."},{"key":"B39","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1159\/000327320","article-title":"All rodents are not the same: a modern synthesis of cortical organization","volume":"78","author":"Krubitzer","year":"2011","journal-title":"Brain Behav. Evol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.brainres.2010.10.015","article-title":"Malformation of the human superior olive in autistic spectrum disorders","volume":"1367","author":"Kulesza","year":"2011","journal-title":"Brain Res."},{"key":"B41","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1016\/S0140-6736(13)61539-1","article-title":"Autism","volume":"383","author":"Lai","year":"2014","journal-title":"Lancet"},{"key":"B42","doi-asserted-by":"publisher","first-page":"921680","DOI":"10.1155\/2011\/921680","article-title":"Autism: a \u201ccritical period\u201d disorder?","volume":"2011","author":"Le Blanc","year":"2011","journal-title":"Neural. Plast."},{"key":"B43","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1007\/s10803-006-0218-7","article-title":"Describing the sensory abnormalities of children and adults with autism","volume":"37","author":"Leekman","year":"2007","journal-title":"J. Autism. Dev. Disord."},{"key":"B44","doi-asserted-by":"publisher","first-page":"13670","DOI":"10.1523\/jneurosci.1516-14.2014","article-title":"A feedforward inhibitory circuit mediates lateral refinement of sensory representation in upper layer 2\/3 of mouse primary auditory cortex","volume":"34","author":"Li","year":"2014","journal-title":"J. Neurosci."},{"key":"B45","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1002\/aur.1337","article-title":"Increased prepulse inhibition and sensitization of the startle reflex in autistic children","volume":"7","author":"Madsen","year":"2014","journal-title":"Autism Res."},{"key":"B46","doi-asserted-by":"publisher","first-page":"3857","DOI":"10.1523\/jneurosci.5027-04.2005","article-title":"Feedforward inhibition of projection neurons by fast-spiking GABA interneurons in the rat striatum in vivo","volume":"25","author":"Mallet","year":"2005","journal-title":"J. Neurosci."},{"key":"B47","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1038\/sj.npp.1301453","article-title":"Abnormal fear conditioning and amygdala processing in an animal model of autism","volume":"33","author":"Markram","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"B48","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3389\/fncel.2014.00023","article-title":"Late onset deficits in synaptic plasticity in the valproic acid rat model of autism","volume":"8","author":"Martin","year":"2014","journal-title":"Front. Cell Neurosci."},{"key":"B49","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.ijdevneu.2004.05.004","article-title":"Maternal administration of thalidomide of valproic acid causes abnormal serotonergic neurons in the offspring: implication for pathogenesis of autism","volume":"23","author":"Miyazaki","year":"2005","journal-title":"Int. J. Dev. Neurosci."},{"key":"B50","doi-asserted-by":"publisher","first-page":"13713","DOI":"10.1523\/jneurosci.0663-13.2013","article-title":"Parvalbumin-expressing inhibitory interneurons in auditory cortex are well-tuned for frequency","volume":"33","author":"Moore","year":"2013","journal-title":"J. Neurosci."},{"key":"B51","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1159\/000341786","article-title":"Effects of rat prenatal exposure to valproic acid on behaviour and neuro-anatomy","volume":"34","author":"Mychasiuk","year":"2012","journal-title":"Dev. Neurosci."},{"key":"B52","doi-asserted-by":"publisher","first-page":"40","DOI":"10.3389\/fnana.2014.00040","article-title":"Trajectory of the main GABAergic interneuron populations from early development to old age in the rat primary auditory cortex","volume":"8","author":"Ouellet","year":"2014","journal-title":"Front. Neuroanat."},{"key":"B53","volume-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2007","edition":"6th Edn"},{"key":"B55","doi-asserted-by":"publisher","first-page":"3621","DOI":"10.1152\/jn.01298.2006","article-title":"Multiparametric auditory receptive field organization across five cortical fields in the albino rat","volume":"97","author":"Polley","year":"2007","journal-title":"J. Neurophysiol."},{"key":"B56","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1111\/j.1601-183x.2009.00487.x","article-title":"Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit","volume":"8","author":"Radyushkin","year":"2009","journal-title":"Genes. Brain Behav."},{"key":"B57","doi-asserted-by":"publisher","first-page":"13501","DOI":"10.1073\/pnas.0704391104","article-title":"Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid","volume":"104","author":"Rinaldi","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"B58","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1093\/cercor\/bhm117","article-title":"Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to valproic acid","volume":"18","author":"Rinaldi","year":"2008","journal-title":"Cereb. Cortex"},{"key":"B59","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/s0890-6238(97)80001-u","article-title":"Linking etiologies in humans and animal models: studies of autism","volume":"11","author":"Rodier","year":"1997","journal-title":"Reprod. Toxicol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1002\/(sici)1096-9861(19960624)370:2247::aid-cne83.0.co;2-2","article-title":"Embryological origin for autism: developmental anomalies of the cranial nerve motor nuclei","volume":"370","author":"Rodier","year":"1996","journal-title":"J. Comp. Neurol."},{"key":"B61","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1023\/A:1023022709710","article-title":"Autism and hearing loss","volume":"29","author":"Rosenhall","year":"1999","journal-title":"J. Autism. Dev. Disord."},{"key":"B610","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.brainres.2013.02.038","article-title":"Altered auditory processing in a mouse model of fragile X syndrome","volume":"1506","author":"Rotschafer","year":"2013","journal-title":"Brain Res."},{"key":"B62","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1034\/j.1601-183x.2003.00037.x","article-title":"Model of autism: increased ratio of excitation\/inhibition in key neural systems","volume":"2","author":"Rubenstein","year":"2003","journal-title":"Genes. Brain Behav."},{"key":"B63","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1109\/embc.2013.6610819","article-title":"Organization of auditory cortex in the albino rat: sound frequency","volume":"59","author":"Sally","year":"1988","journal-title":"J. Neurophysiol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.conb.2009.05.014","article-title":"Tuning up the developing auditory CNS","volume":"19","author":"Sanes","year":"2009","journal-title":"Curr. Opin. Neurobiol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1038\/sj.npp.1300518","article-title":"Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism","volume":"30","author":"Schneider","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"B66","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.expneurol.2013.01.021","article-title":"Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: implications for autism spectrum disorders","volume":"247","author":"Sgad\u00f2","year":"2013","journal-title":"Exp. Neurol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/neuro.19.001.2009","article-title":"Enhanced long-term microcircuit plasticity in the valproic Acid animal model of autism","volume":"1","author":"Silva","year":"2009","journal-title":"Front. Synaptic Neurosci."},{"key":"B68","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1016\/j.cell.2008.05.054","article-title":"Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity","volume":"134","author":"Sugiyama","year":"2008","journal-title":"Cell."},{"key":"B69","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.cell.2008.05.054","article-title":"Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse","volume":"467","author":"Tamamaki","year":"2003","journal-title":"J. Comp. Neurol."},{"key":"B70","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1097\/01.aud.0000224981.60575.d8","article-title":"Auditory characteristics of children with autism","volume":"27","author":"Tharpe","year":"2006","journal-title":"Ear Hear."},{"key":"B19","doi-asserted-by":"publisher","first-page":"e73114","DOI":"10.1371\/journal.pone.0073144","article-title":"A behavioral evaluation of sex differences in a mouse model of severe neuronal migration disorder","volume":"8","author":"Truong","year":"2013","journal-title":"PLoS One"},{"key":"B71","doi-asserted-by":"publisher","first-page":"13097","DOI":"10.1523\/jneurosci.1341-11.2011","article-title":"Synaptic and intrinsic balancing during postnatal development in rat pups exposed to valproic acid in utero","volume":"31","author":"Walcott","year":"2011","journal-title":"J. Neurosci."},{"key":"B72","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/s0006-8993(02)02926-8","article-title":"Gamma-aminobutyric acid circuits shape response properties of auditory cortex neurons","volume":"944","author":"Wang","year":"2002","journal-title":"Brain Res."},{"key":"B73","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1017\/s001216220100038x","article-title":"Fetal valproate syndrome and autism: additional evidence of an association","volume":"43","author":"Williams","year":"2001","journal-title":"Dev. Med. Child Neurol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1002\/cne.22229","article-title":"Immunochemical characterization of inhibitory mouse cortical neurons: three chemically distinct classes of inhibitory cells","volume":"518","author":"Xu","year":"2010","journal-title":"J. Comp. Neurol."},{"key":"B75","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.3410\/f.1002598.29107","article-title":"Persistent and specific influences of early acoustic environments on primary auditory cortex","volume":"4","author":"Zhang","year":"2001","journal-title":"Nat. Neurosci."},{"key":"B76","doi-asserted-by":"publisher","first-page":"15935","DOI":"10.1073\/pnas.0707348104","article-title":"Intensive training in adults refines AI representations degraded in an early postnatal critical period","volume":"104","author":"Zhou","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U S A"}],"container-title":["Frontiers in Systems Neuroscience"],"original-title":[],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T15:26:50Z","timestamp":1567351610000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/Article\/10.3389\/fnsys.2015.00158\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,16]]},"references-count":75,"URL":"https:\/\/doi.org\/10.3389\/fnsys.2015.00158","relation":{},"ISSN":["1662-5137"],"issn-type":[{"value":"1662-5137","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,16]]}}}