{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:08:40Z","timestamp":1753891720256,"version":"3.41.2"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T00:00:00Z","timestamp":1627257600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:p>The peak rate of fat oxidation (PFO) achieved during a graded exercise test is an important indicator of metabolic health. In healthy individuals, there is a significant positive association between PFO and total daily fat oxidation (FO). However, conditions resulting in metabolic dysfunction may cause a disconnect between PFO and non-exercise FO. Ten adult men with chronic thoracic spinal cord injury (SCI) completed a graded arm exercise test. On a separate day following an overnight fast (\u2265 10 h), they rested for 60 min before ingesting a liquid mixed meal (600 kcal; 35% fat, 50% carbohydrate, 15% protein). Expired gases were collected and indirect calorimetry data used to determine FO at rest, before and after feeding, and during the graded exercise test. Participants had \u201cgood\u201d cardiorespiratory fitness (VO<jats:sub>2peak<\/jats:sub>: 19.2 \u00b1 5.2 ml\/kg\/min) based on normative reference values for SCI. There was a strong positive correlation between PFO (0.30 \u00b1 0.08 g\/min) and VO<jats:sub>2peak<\/jats:sub> (<jats:italic>r<\/jats:italic> = 0.86, <jats:italic>p<\/jats:italic> = 0.002). Additionally, postabsorptive FO at rest was significantly and positively correlated with postprandial peak FO (<jats:italic>r<\/jats:italic> = 0.77, <jats:italic>p<\/jats:italic> = 0.01). However, PFO was not significantly associated with postabsorptive FO at rest (0.08 \u00b1 0.02 g\/min; <jats:italic>p<\/jats:italic> = 0.97), postprandial peak FO (0.10 \u00b1 0.03 g\/min; <jats:italic>p<\/jats:italic> = 0.43), or incremental area under the curve postprandial FO (<jats:italic>p<\/jats:italic> = 0.22). It may be advantageous to assess both postabsorptive FO at rest and PFO in those with SCI to gain a more complete picture of their metabolic flexibility and long-term metabolic health.<\/jats:p>","DOI":"10.3389\/fnut.2021.703652","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T05:17:50Z","timestamp":1627276670000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Neither Postabsorptive Resting Nor Postprandial Fat Oxidation Are Related to Peak Fat Oxidation in Men With Chronic Paraplegia"],"prefix":"10.3389","volume":"8","author":[{"given":"Kevin A.","family":"Jacobs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David W.","family":"McMillan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"Maher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James L. 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