{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T16:40:24Z","timestamp":1774975224974,"version":"3.50.1"},"reference-count":69,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The primary treatment for non-alcoholic fatty liver disease (NAFLD) is modifying lifestyle through dietary or exercise interventions. In recent decades, it has received increasing attention. However, the lack of bibliometric analysis has posed a challenge for researchers seeking to understand the overall trends in this field.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>As of February 3rd, 2024, 876 articles on treating NAFLD through diet or exercise therapy from 2013 to 2023 had been retrieved. Two software tools, VOSviewer and CiteSpace, were utilized to analyze the growth of publications, countries, institutions, authors, journals, citations, and keywords. Additionally, the keywords with strong citation burstiness were identified to determine the changes and future trends of research hotspots in this field.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>China had the highest number of articles, followed by the United States and South Korea. Yonsei University and <jats:italic>Nutrient<\/jats:italic>s were the institutions and journals with the most significant contributions. Professor Younossi Zobair M, from the United States, is the most prolific author in this field. Through analyzing the keywords, three research hotspots were identified: research on the pathogenesis of NAFLD, research on the treatment modalities of NAFLD, and research on the risk factors and diagnosis methods of NAFLD. In recent years, the research emphasis in this field has changed, suggesting that future research will focus on two frontier keywords: \u201coxidative stress\u201d and \u201caerobic capacity.\u201d<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the past eleven years, the attention in this field was still rising, and the authors, journals, countries and so on had formed a considerable cooperative relationship. There were also many highly influential and productive researchers in this field. It is speculated that new research will continue around \u201caerobic exercise\u201d and \u201coxidative stress\u201d in the future.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnut.2024.1326092","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T04:53:37Z","timestamp":1712033617000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Progress and hotspot of diet or exercise therapy in the treatment of non-alcoholic fatty liver disease"],"prefix":"10.3389","volume":"11","author":[{"given":"Xinyu","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yalan","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hualing","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fen","family":"Rong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leping","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shenyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengfu","family":"You","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baocheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,4,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3760\/cma.j.issn.1007-3418.2018.03.008","article-title":"Guidelines of prevention and treatment for nonalcoholic fatty liver disease: a 2018 update","volume":"26","year":"2018","journal-title":"Zhonghua Gan Zang Bing Za Zhi"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1002\/hep.29367","article-title":"The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases","volume":"67","author":"Chalasani","year":"2018","journal-title":"Hepatology"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1097\/HEP.0000000000000004","article-title":"The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review","volume":"77","author":"Younossi","year":"2023","journal-title":"Hepatology"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"201","DOI":"10.2478\/v10222-012-0100-6","article-title":"Kazimierz (Casimir) funk \u2013 Pioneer in Vitaminology \u2013 101 anniversary of his discovery \u2013 special note","volume":"63","author":"Berger","year":"2013","journal-title":"Pol J Food Nutr"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1016\/0026-0495(65)90004-1","article-title":"Serum cholesterol response to changes in the diet: IV. Particular saturated fatty acids in the diet","volume":"14","author":"Keys","year":"1965","journal-title":"Metabolism"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/00017285-196900410-00004","article-title":"Sucrose and heart Disease","volume":"4","author":"Yudkin","year":"1969","journal-title":"Nutr. Today"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1079\/PNS2005464","article-title":"Micronutrients: dietary intake v. supplement use","volume":"64","author":"Woodside","year":"2005","journal-title":"Proc Nutr Soc"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1080\/02640411003671212","article-title":"The ABC of physical activity for health: a consensus statement from the British Association of Sport and Exercise Sciences","volume":"28","author":"O'Donovan","year":"2010","journal-title":"J Sports Sci"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1007\/s11162-012-9264-5","article-title":"The use of Bibliometrics to measure research performance in education sciences","volume":"54","author":"Diem","year":"2012","journal-title":"Res High Educ"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1007\/s11192-014-1484-3","article-title":"Scientometrics and information retrieval: weak-links revitalized","volume":"102","author":"Mayr","year":"2014","journal-title":"Scientometrics"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s11192-011-0406-x","article-title":"The field-standardized average impact of national research systems compared to world average: the case of Italy","volume":"88","author":"Abramo","year":"2011","journal-title":"Scientometrics"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1002\/asi.20317","article-title":"CiteSpace II: detecting and visualizing emerging trends and transient patterns in scientific literature","volume":"57","author":"Chen","year":"2006","journal-title":"J Am Soc Inf Sci Technol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s11192-009-0146-3","article-title":"Software survey: VOSviewer, a computer program for bibliometric mapping","volume":"84","author":"van Eck","year":"2010","journal-title":"Scientometrics"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1111\/apt.17308","article-title":"Vigorous physical activity provides protection against all-cause deaths among adults patients with nonalcoholic fatty liver disease (NAFLD)","volume":"57","author":"Henry","year":"2023","journal-title":"Aliment Pharmacol Ther"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.jnutbio.2006.12.006","article-title":"Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition","volume":"18","author":"Cave","year":"2007","journal-title":"J Nutr Biochem"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1172\/JCI21625","article-title":"Increased oxidative stress in obesity and its impact on metabolic syndrome","volume":"114","author":"Furukawa","year":"2004","journal-title":"J Clin Invest"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"e180","DOI":"10.1111\/liv.12523","article-title":"Are oxidative stress mechanisms the common denominator in the progression from hepatic steatosis towards non-alcoholic steatohepatitis (NASH)?","volume":"34","author":"Tariq","year":"2014","journal-title":"Liver Int"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/j.nut.2009.02.008","article-title":"Efficacy and safety of very-low-calorie diet in Taiwanese: a multicenter randomized, controlled trial","volume":"25","author":"Lin","year":"2009","journal-title":"Nutrition"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"S437","DOI":"10.1016\/S0168-8278(22)01209-0","article-title":"12-week very low calorie diet in NAFLD induces rapid improvements in biomarkers of necro-apoptosis and fibrogenesis of a magnitude comparable to those seen in phase 2 drug trials","volume":"77","author":"Scragg","year":"2022","journal-title":"J Hepatol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2023\/4197955","article-title":"Effects of different vegetable oils on the nonalcoholic fatty liver Disease in C57\/BL mice","volume":"2023","author":"Manca","year":"2023","journal-title":"Evid Based Complement Alternat Med"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s12986-023-00733-4","article-title":"The effect of DASH diet on glycemic response, meta-inflammation and serum LPS in obese patients with NAFLD: a double-blind controlled randomized clinical trial","volume":"20","author":"Rooholahzadegan","year":"2023","journal-title":"Nutr Metab (Lond)"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"e13024","DOI":"10.1111\/obr.13024","article-title":"Beneficial effects of the ketogenic diet on nonalcoholic fatty liver disease: a comprehensive review of the literature","volume":"21","author":"Watanabe","year":"2020","journal-title":"Obes Rev"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1186\/s40795-022-00625-5","article-title":"Adherence to low carbohydrate diets and non-alcoholic fatty liver disease: a case control study","volume":"8","author":"Yaghoubi","year":"2022","journal-title":"BMC Nutr"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"2749","DOI":"10.4254\/wjh.v7.i27.2749","article-title":"Vitamin E reduces liver stiffness in nonalcoholic fatty liver disease","volume":"7","author":"Fukui","year":"2015","journal-title":"World J Hepatol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1016\/j.jhep.2022.06.033","article-title":"Vitamin B(12) and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation","volume":"77","author":"Tripathi","year":"2022","journal-title":"J Hepatol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"193","DOI":"10.12047\/j.cjap.6282.2022.046","article-title":"Effects of aerobic exercise on CNPY2-PERK pathway in the liver of mice with non-alcoholic fatty liver disease","volume":"38","author":"Li","year":"2022","journal-title":"Zhongguo Ying Yong Sheng Li Xue Za Zhi"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"901827","DOI":"10.3389\/fgene.2022.901827","article-title":"Effect of aerobic exercise on lipid metabolism in rats with NAFLD","volume":"13","author":"Zhou","year":"2022","journal-title":"Front Genet"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"e00316","DOI":"10.14309\/ctg.0000000000000316","article-title":"Moderate-intensity aerobic vs resistance exercise and dietary modification in patients with nonalcoholic fatty liver Disease: a randomized clinical trial","volume":"12","author":"Charatcharoenwitthaya","year":"2021","journal-title":"Clin Transl Gastroenterol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"e20399","DOI":"10.1097\/MD.0000000000020399","article-title":"Simple resistance exercise decreases cytokeratin 18 and fibroblast growth factor 21 levels in patients with nonalcoholic fatty liver disease: a retrospective clinical study","volume":"99","author":"Takahashi","year":"2020","journal-title":"Medicine"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2123","DOI":"10.1007\/s10620-022-07779-z","article-title":"High-intensity interval training is safe, feasible and efficacious in nonalcoholic steatohepatitis: a randomized controlled trial","volume":"68","author":"Keating","year":"2023","journal-title":"Dig Dis Sci"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.cmet.2022.12.001","article-title":"Effect of alternate day fasting combined with aerobic exercise on non-alcoholic fatty liver disease: a randomized controlled trial","volume":"35","author":"Ezpeleta","year":"2023","journal-title":"Cell Metab"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1038\/oby.2008.201","article-title":"Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function","volume":"16","author":"Larson-Meyer","year":"2008","journal-title":"Obesity (Silver Spring)"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"167","DOI":"10.34172\/mejdd.2022.270","article-title":"Non-alcoholic fatty liver Disease and steatohepatitis: risk factors and pathophysiology","volume":"14","author":"Akter","year":"2022","journal-title":"Middle East J Dig Dis"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.gendis.2023.03.023","article-title":"DNA methylation of SMPD3-based diagnostic biomarkers of NASH and mild fibrosis","volume":"11","author":"Wu","year":"2024","journal-title":"Genes Dis"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"6488","DOI":"10.1038\/s41598-023-33753-4","article-title":"Waist circumference mediates the association between rs1260326 in GCKR gene and the odds of lean NAFLD","volume":"13","author":"Wu","year":"2023","journal-title":"Sci Rep"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1186\/s13578-021-00701-6","article-title":"Effect of exercise and diet intervention in NAFLD and NASH via GAB2 methylation","volume":"11","author":"Wu","year":"2021","journal-title":"Cell Biosci"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fpubh.2022.1003505","article-title":"The gender-specific bidirectional relations between chronic diseases and total bilirubin\/urea in the elderly population: a 3-year longitudinal study","volume":"10","author":"Wu","year":"2022","journal-title":"Front Public Health"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1026725","DOI":"10.3389\/fgene.2022.1026725","article-title":"Genetic variation in TBC1 domain family member 1 gene associates with the risk of lean NAFLD via high-density lipoprotein","volume":"13","author":"Wu","year":"2023","journal-title":"Front Genet"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"970854","DOI":"10.3389\/fgene.2022.970854","article-title":"Fasting glucose mediates the influence of genetic variants of SOD2 gene on lean non-alcoholic fatty liver disease","volume":"13","author":"Wu","year":"2022","journal-title":"Front Genet"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1007\/s12263-014-0392-8","article-title":"Influence of dietary pattern, physical activity, and I148M PNPLA3 on steatosis severity in at-risk adolescents","volume":"9","author":"Nobili","year":"2014","journal-title":"Genes Nutr"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"e1001324","DOI":"10.1371\/journal.pgen.1001324","article-title":"Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits","volume":"7","author":"Speliotes","year":"2011","journal-title":"PLoS Genet"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1038\/ng.2901","article-title":"Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease","volume":"46","author":"Kozlitina","year":"2014","journal-title":"Nat Genet"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1053\/j.gastro.2020.01.049","article-title":"Nonalcoholic fatty liver Disease: modulating gut microbiota to improve severity?","volume":"158","author":"Aron-Wisnewsky","year":"2020","journal-title":"Gastroenterology"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"211","DOI":"10.5114\/ceh.2022.119265","article-title":"The TM6SF2 variant as a risk factor for hepatocellular carcinoma development in chronic liver disease patients","volume":"8","author":"Raia","year":"2022","journal-title":"Clin Exp Hepatol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1038\/s41575-018-0014-9","article-title":"Noninvasive biomarkers in NAFLD and NASH - current progress and future promise","volume":"15","author":"Wong","year":"2018","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.metabol.2017.11.002","article-title":"Nicotinic acetylcholine receptor \u03b17 subunit improves energy homeostasis and inhibits inflammation in nonalcoholic fatty liver disease","volume":"79","author":"Li","year":"2018","journal-title":"Metabolism"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1016\/j.jhep.2018.01.015","article-title":"High red and processed meat consumption is associated with non-alcoholic fatty liver disease and insulin resistance","volume":"68","author":"Zelber-Sagi","year":"2018","journal-title":"J Hepatol"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1111\/liv.14164","article-title":"Association between nut consumption and non-alcoholic fatty liver disease in adults","volume":"39","author":"Zhang","year":"2019","journal-title":"Liver Int"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.3390\/antiox12071318","article-title":"Adherence to Mediterranean diet: any association with NAFLD?","volume":"12","author":"Barrea","year":"2023","journal-title":"Antioxidants."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.3390\/antiox11081440","article-title":"Increased adherence to the Mediterranean diet after lifestyle intervention improves oxidative and inflammatory status in patients with non-alcoholic fatty liver Disease","volume":"11","author":"Monserrat-Mesquida","year":"2022","journal-title":"Antioxidants"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"465","DOI":"10.3390\/nu10040465","article-title":"A Mediterranean diet model in Australia: strategies for translating the traditional Mediterranean diet into a multicultural setting","volume":"10","author":"George","year":"2018","journal-title":"Nutrients"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3389\/fnut.2023.1163516","article-title":"The effect of the dietary approaches to stop hypertension diet on total antioxidant capacity, superoxide dismutase, catalase, and body composition in patients with non-alcoholic fatty liver disease: a randomized controlled trial","volume":"10","author":"Zare","year":"2023","journal-title":"Front Nutr"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"141","DOI":"10.3390\/jcm9010141","article-title":"Randomised clinical trial: calorie restriction regimen with tomato juice supplementation ameliorates oxidative stress and preserves a proper immune surveillance modulating mitochondrial bioenergetics of T-lymphocytes in obese children affected by non-alcoholic fatty liver Disease (NAFLD)","volume":"9","author":"Negri","year":"2020","journal-title":"J Clin Med"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.3390\/nu11051101","article-title":"Dietary carotenoids and non-alcoholic fatty liver Disease among US adults, NHANES 2003-2014","volume":"11","author":"Christensen","year":"2019","journal-title":"Nutrients"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1007\/s00394-018-1678-1","article-title":"Higher serum carotenoids associated with improvement of non-alcoholic fatty liver disease in adults: a prospective study","volume":"58","author":"Xiao","year":"2019","journal-title":"Eur J Nutr"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3389\/fnut.2021.795391","article-title":"Association of Serum Vitamin C with NAFLD and MAFLD among adults in the United States","volume":"8","author":"Xie","year":"2022","journal-title":"Front Nutr"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"547","DOI":"10.3390\/nu10050547","article-title":"A vitamin E-enriched antioxidant diet interferes with the acute adaptation of the liver to physical exercise in mice","volume":"10","author":"Hoene","year":"2018","journal-title":"Nutrients"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"e14744","DOI":"10.1111\/ijcp.14744","article-title":"Omega 3-rich Camelina sativa oil in the context of a weight loss program improves glucose homeostasis, inflammation and oxidative stress in patients with NAFLD: a randomised placebo-controlled clinical trial","volume":"75","author":"Musazadeh","year":"2021","journal-title":"Int J Clin Pract"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"122","DOI":"10.37527\/2023.73.2.004","article-title":"Efficacy of nutrition therapy with food rich in methionine for treating nonalcoholic fatty liver","volume":"73","author":"Morales-Romero","year":"2023","journal-title":"Arch Latinoam Nutr"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3389\/fnut.2022.1074494","article-title":"Association between flavonoid and subclasses intake and metabolic associated fatty liver disease in US adults: Results from National Health and nutrition examination survey 2017-2018","volume":"9","author":"Tong","year":"2022","journal-title":"Front Nutr"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1080\/13813455.2018.1441872","article-title":"Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis, oxidative stress, and inflammatory biomarkers in the liver of old rats with non-alcoholic fatty liver disease","volume":"125","author":"Hajighasem","year":"2019","journal-title":"Arch Physiol Biochem"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"121064","DOI":"10.1016\/j.lfs.2022.121064","article-title":"Creatine supplementation protects against diet-induced non-alcoholic fatty liver but exacerbates alcoholic fatty liver","volume":"310","author":"Marinello","year":"2022","journal-title":"Life Sci"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"8509","DOI":"10.3390\/ijms24108509","article-title":"Twelve weeks of high-intensity interval training alters adipose tissue gene expression but not Oxylipin levels in people with non-alcoholic fatty liver Disease","volume":"24","author":"Csader","year":"2023","journal-title":"Int J Mol Sci"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"100709","DOI":"10.1016\/j.aohep.2022.100709","article-title":"Endurance exercise-mediated metabolic reshuffle attenuates high-caloric diet-induced non-alcoholic fatty liver disease","volume":"27","author":"Cook","year":"2022","journal-title":"Ann Hepatol"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"588502","DOI":"10.3389\/fendo.2020.588502","article-title":"Aerobic exercise training exerts beneficial effects upon oxidative metabolism and non-enzymatic antioxidant defense in the liver of leptin deficiency mice","volume":"11","author":"Fernandes","year":"2020","journal-title":"Front Endocrinol"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"88","DOI":"10.3109\/13697137.2012.662251","article-title":"Effect of exercise training and isoflavones on hepatic steatosis in overweight postmenopausal women","volume":"16","author":"Barsalani","year":"2013","journal-title":"Climacteric"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"7687","DOI":"10.26355\/eurrev_202112_27615","article-title":"Intervention effects of four exercise modalities on nonalcoholic fatty liver disease: a systematic review and Bayesian network meta-analysis","volume":"25","author":"Zhou","year":"2021","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.metabol.2016.12.006","article-title":"Effects of lifestyle interventions on clinical characteristics of patients with non-alcoholic fatty liver disease: a meta-analysis","volume":"68","author":"Katsagoni","year":"2017","journal-title":"Metabolism"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1210\/clinem\/dgab795","article-title":"The effect of high-intensity interval training vs moderate-intensity continuous training on liver fat: a systematic review and Meta-analysis","volume":"107","author":"Sabag","year":"2022","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Frontiers in Nutrition"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2024.1326092\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T04:55:54Z","timestamp":1712033754000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2024.1326092\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,2]]},"references-count":69,"alternative-id":["10.3389\/fnut.2024.1326092"],"URL":"https:\/\/doi.org\/10.3389\/fnut.2024.1326092","relation":{},"ISSN":["2296-861X"],"issn-type":[{"value":"2296-861X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,2]]},"article-number":"1326092"}}