{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:25:40Z","timestamp":1785547540741,"version":"3.56.0"},"reference-count":46,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T00:00:00Z","timestamp":1718755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Sleep disorders is a worldwide public health problem. We sought to examine the association between sarcopenia, a decline in skeletal muscle mass and function, and sleep disorders within the adult demographic of the United States during the period spanning 2011 to 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Diagnosis of sarcopenia and sleep disorders was ascertained through appropriate calculations and a structured questionnaire. The primary correlation analysis was conducted using a weighted multivariate logistic regression model. Furthermore, to confirm the presence of a potential non-linear association between sarcopenia and sleep disorders, additional analyses were performed using multivariate logistic regression and restricted cubic spline (RCS) regression with dose-response curve analysis. Subgroup analyses were also conducted to explore the influence of relevant socio-demographic factors and other covariates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The final analysis encompassed 5,616 participants. Model 4, inclusive of all pertinent covariates, revealed a positive correlation between sarcopenia and sleep disorders, yielding an odds ratio (OR) of 1.732 (95% CI: 1.182\u20132.547; <jats:italic>P<\/jats:italic> = 0.002). Further analysis, utilizing the restricted cubic spline model, indicated a decreasing trend in sleep disorders as sarcopenia indices rose. Stratified analyses across diverse variables underscored the significant impact of sarcopenia on sleep disorders prevalence in several subgroups. Specifically, males, individuals aged 40 and above, non-Hispanic whites, those with high school education or equivalent, unmarried individuals, obese individuals (BMI \u2265 30), alcohol drinkers, former smokers, diabetics, and those engaging in less rigorous recreational activities exhibited a more pronounced association between sarcopenia and sleep disorders. The incidence of sleep disorders exhibited an upward trend as the incidence of sarcopenia declined among study participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In summary, our study provides evidence of an association between sarcopenia and the prevalence of sleep disorders, with a negative correlation observed between the sarcopenia index and the odds ratio of sleep disorders. These findings suggest that maintaining optimal muscle mass may have a beneficial impact on sleep-related issues. In terms of exploring the mechanisms underlying the relationship between sarcopenia and sleep disorders, more in-depth research is warranted to ascertain the definitive causal relationship.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnut.2024.1415743","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T09:42:51Z","timestamp":1718790171000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Association between sarcopenia and sleep disorders: a cross-sectional population based study"],"prefix":"10.3389","volume":"11","author":[{"given":"Kepeng","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhui","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binfei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianxue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaozu","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,6,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/S2213-8587(14)70012-9","article-title":"The metabolic burden of sleep loss","volume":"3","author":"Schmid","year":"2015","journal-title":"Lancet Diabet Endocrinol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.2147\/NSS.S295537","article-title":"Prevalence of insufficient sleep and its associated factors among working adults in Malaysia","volume":"13","author":"Chan","year":"2021","journal-title":"Nat Sci Sleep."},{"key":"B3","doi-asserted-by":"publisher","first-page":"137","DOI":"10.15585\/mmwr.mm6506a1","article-title":"Prevalence of healthy sleep duration among adults\u2013United States, 2014","volume":"65","author":"Liu","year":"2016","journal-title":"Morbid Mortal Weekly Rep."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1378\/chest.14-0970","article-title":"International classification of sleep disorders-third edition: highlights and modifications","volume":"146","author":"Sateia","year":"2014","journal-title":"Chest."},{"key":"B5","doi-asserted-by":"publisher","first-page":"51","DOI":"10.4103\/2141-9248.109488","article-title":"Study of sleep habits and sleep problems among medical students of Pravara Institute of Medical Sciences Loni, Western Maharashtra, India","volume":"3","author":"Giri","year":"2013","journal-title":"Ann Med Health Sci Res."},{"key":"B6","doi-asserted-by":"publisher","first-page":"20692","DOI":"10.3390\/jcm12020692","article-title":"Insomnia, daytime sleepiness, and quality of life among 20,139 college students in 60 countries around the world-a 2016-2021 study","volume":"12","author":"Babicki","year":"2023","journal-title":"J Clin Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.cger.2017.02.003","article-title":"Sarcopenia","volume":"33","author":"Woo","year":"","journal-title":"Clin Geriatr Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"155533","DOI":"10.1016\/j.metabol.2023.155533","article-title":"Epidemiology of sarcopenia: Prevalence, risk factors, and consequences","volume":"2023","author":"Yuan","year":"2023","journal-title":"Metabolism"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1210\/clinem\/dgab884","article-title":"Prevalence and risk factors of sarcopenia in patients with diabetes: a meta-analysis","volume":"107","author":"Feng","year":"2022","journal-title":"J Clin Endocrinol Metab."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1038\/s41430-022-01085-7","article-title":"Pre-treatment sarcopenic assessments as a prognostic factor for gynaecology cancer outcomes: systematic review and meta-analysis","volume":"76","author":"Sutton","year":"2022","journal-title":"Eur J Clin Nutr."},{"key":"B11","doi-asserted-by":"publisher","first-page":"194077","DOI":"10.3390\/nu14194077","article-title":"Prevalence of sarcopenia and its impact on cardiovascular events and mortality among dialysis patients: a systematic review and meta-analysis","volume":"14","author":"Wathanavasin","year":"2022","journal-title":"Nutrients"},{"key":"B12","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.surg.2022.02.014","article-title":"Short- and long-term impact of sarcopenia on outcomes after emergency laparotomy: a systematic review and meta-analysis","volume":"172","author":"Park","year":"2022","journal-title":"Surgery."},{"key":"B13","doi-asserted-by":"publisher","first-page":"e00584","DOI":"10.14309\/ctg.0000000000000584","article-title":"Prevalence of sarcopenia in liver cirrhosis: a systematic review and meta-analysis","volume":"14","author":"Mazeaud","year":"2023","journal-title":"Clin Transl Gastroenterol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"4291","DOI":"10.3390\/nu13124291","article-title":"Associated factors of sarcopenia in community-dwelling older adults: a systematic review and meta-analysis","volume":"13","author":"Gao","year":"2021","journal-title":"Nutrients"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-023-04034-7","article-title":"Correlation between bone mineral density and sarcopenia in US adults: a population-based study","author":"Cheng","year":"","journal-title":"J Orthop Surg Res"},{"key":"B16","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1093\/gerona\/glu010","article-title":"The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates","volume":"69","author":"Studenski","year":"2014","journal-title":"J Gerontol Ser A Biol Sci Med Sci."},{"key":"B17","doi-asserted-by":"publisher","first-page":"350","DOI":"10.2337\/dc20-1485","article-title":"Association of serum 25-hydroxyvitamin D concentrations with all-cause and cause-specific mortality among individuals with diabetes","volume":"44","author":"Wan","year":"2021","journal-title":"Diabet Care."},{"key":"B18","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.mehy.2011.04.017","article-title":"Sleep and muscle recovery: endocrinological and molecular basis for a new and promising hypothesis","volume":"77","author":"Dattilo","year":"2011","journal-title":"Med Hypotheses."},{"key":"B19","doi-asserted-by":"publisher","first-page":"615","DOI":"10.5664\/jcsm.4770","article-title":"Improved sleep quality is associated with reductions in depression and PTSD arousal symptoms and increases in IGF-1 concentrations","volume":"11","author":"Rusch","year":"2015","journal-title":"J Clin Sleep Med."},{"key":"B20","doi-asserted-by":"publisher","first-page":"26557","DOI":"10.7554\/eLife.26557","article-title":"Bmal1 function in skeletal muscle regulates sleep","volume":"6","author":"Ehlen","year":"2017","journal-title":"eLife"},{"key":"B21","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1038\/nature00965","article-title":"Coordination of circadian timing in mammals","volume":"418","author":"Reppert","year":"2002","journal-title":"Nature."},{"key":"B22","doi-asserted-by":"publisher","first-page":"7742","DOI":"10.1038\/s41598-023-34115-w","article-title":"Prediction of mammalian tissue-specific CLOCK-BMAL1 binding to E-box DNA motifs","volume":"13","author":"Marri","year":"2023","journal-title":"Sci Rep."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1136\/bmjresp-2022-001506","article-title":"Sleep apnoea and hypoventilation in patients with five major types of muscular dystrophy","volume":"10","author":"Li","year":"2023","journal-title":"Br Med J Open Respirat Res"},{"key":"B24","doi-asserted-by":"publisher","first-page":"219","DOI":"10.4082\/kjfm.17.0030","article-title":"Association between sleep duration and body composition measures in Korean adults: the Korea National Health and Nutrition Examination Survey 2010","volume":"39","author":"Kim","year":"2018","journal-title":"Korean J Fam Med."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1002\/jcsm.12735","article-title":"Sleep duration and progression to sarcopenia in Japanese community-dwelling older adults: a 4 year longitudinal study","volume":"12","author":"Nakakubo","year":"2021","journal-title":"J Cachexia Sarcopenia Muscle."},{"key":"B26","doi-asserted-by":"publisher","first-page":"e6268","DOI":"10.1097\/MD.0000000000006268","article-title":"Association between sleep duration and sarcopenia among community-dwelling older adults: a cross-sectional study","volume":"96","author":"Hu","year":"2017","journal-title":"Medicine."},{"key":"B27","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/2046-2395-3-9","article-title":"It is not just muscle mass: a review of muscle quality, composition and metabolism during ageing as determinants of muscle function and mobility in later life","volume":"3","author":"McGregor","year":"2014","journal-title":"Long Healthspan."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.2337\/dc11-2202","article-title":"Role of muscle mass and muscle quality in the association between diabetes and gait speed","volume":"35","author":"Volpato","year":"2012","journal-title":"Diabet Care."},{"key":"B29","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/j.jamda.2013.02.006","article-title":"Patients with type 2 diabetes show a greater decline in muscle mass, muscle strength, and functional capacity with aging","volume":"14","author":"Leenders","year":"2013","journal-title":"J Am Med Dir Assoc."},{"key":"B30","doi-asserted-by":"publisher","first-page":"S157","DOI":"10.2337\/dc09-S302","article-title":"Skeletal muscle insulin resistance is the primary defect in type 2 diabetes","volume":"32","author":"DeFronzo","year":"2009","journal-title":"Diabet Care."},{"key":"B31","doi-asserted-by":"publisher","first-page":"13591053221140805","DOI":"10.1177\/13591053221140805","article-title":"Understanding the relationship between sleep and quality of life in type 2 diabetes: a systematic review of the literature","volume":"2023","author":"Laverty","year":"2023","journal-title":"J Health Psychol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.sleep.2020.04.022","article-title":"Health-related quality of life and sleep quality among North Indian type 2 diabetes mellitus patients: evidence from a cross-sectional study","volume":"73","author":"Azharuddin","year":"2020","journal-title":"Sleep Med."},{"key":"B33","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1111\/jdi.14007","article-title":"Associations of sleep quality with the skeletal muscle strength in patients with type 2 diabetes with poor glycemic control","volume":"14","author":"Hayashi","year":"2023","journal-title":"J Diabet Investig."},{"key":"B34","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1002\/oby.21321","article-title":"Elevated ghrelin predicts food intake during experimental sleep restriction","volume":"24","author":"Broussard","year":"2016","journal-title":"Obesity."},{"key":"B35","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1038\/ijo.2013.114","article-title":"Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals","volume":"38","author":"St-Onge","year":"2014","journal-title":"Int J Obes."},{"key":"B36","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/S1087-0792(03)90005-0","article-title":"Insomnia, alcoholism and relapse","volume":"7","author":"Brower","year":"2003","journal-title":"Sleep Med Rev."},{"key":"B37","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1186\/1471-2458-14-1143","article-title":"Associations of physical activity with sleep satisfaction, perceived stress, and problematic Internet use in Korean adolescents","volume":"14","author":"Park","year":"2014","journal-title":"BMC Publ Health."},{"key":"B38","doi-asserted-by":"publisher","first-page":"3112","DOI":"10.1007\/s12035-017-0516-4","article-title":"Exercise as a positive modulator of brain function","volume":"55","author":"Alkadhi","year":"2018","journal-title":"Mol Neurobiol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"643","DOI":"10.23736\/S0022-4707.16.06159-4","article-title":"One night of partial sleep deprivation increased biomarkers of muscle and cardiac injuries during acute intermittent exercise","volume":"57","author":"Mejri","year":"2017","journal-title":"J Sports Med Phys Fitness."},{"key":"B40","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s12950-015-0102-3","article-title":"Effects of exercise on brain and peripheral inflammatory biomarkers induced by total sleep deprivation in rats","volume":"12","author":"Chennaoui","year":"2015","journal-title":"J Inflamm."},{"key":"B41","doi-asserted-by":"publisher","first-page":"M326","DOI":"10.1093\/gerona\/57.5.M326","article-title":"Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study","volume":"57","author":"Visser","year":"2002","journal-title":"J Gerontol Ser A Biol Sci Med Sci."},{"key":"B42","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.jamda.2011.01.003","article-title":"Sarcopenia: an undiagnosed condition in older adults Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia","volume":"12","author":"Fielding","year":"2011","journal-title":"J Am Med Direct Assoc."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1007\/s12603-018-1139-9","article-title":"International Clinical Practice Guidelines for Sarcopenia (ICFSR): screening, diagnosis and management","volume":"22","author":"Dent","year":"2018","journal-title":"J Nutr Health Aging."},{"key":"B44","doi-asserted-by":"publisher","first-page":"565","DOI":"10.4239\/wjd.v14.i5.565","article-title":"Exercise therapy for sarcopenia and diabetes","volume":"14","author":"Lim","year":"2023","journal-title":"World J Diabet."},{"key":"B45","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/s12603-023-1888-y","article-title":"Comparing prevalence of sarcopenia using twelve sarcopenia definitions in a large multinational European population of community-dwelling older adults","volume":"27","author":"Stuck","year":"2023","journal-title":"J Nutr Health Aging."},{"key":"B46","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.2147\/NSS.S361925","article-title":"Both short and long sleep durations are risk factors for sarcopenia in suburban-dwelling older Chinese individuals: a 3-year longitudinal study","volume":"14","author":"Han","year":"2022","journal-title":"Nat Sci Sleep."}],"container-title":["Frontiers in Nutrition"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2024.1415743\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T09:42:54Z","timestamp":1718790174000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2024.1415743\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,19]]},"references-count":46,"alternative-id":["10.3389\/fnut.2024.1415743"],"URL":"https:\/\/doi.org\/10.3389\/fnut.2024.1415743","relation":{},"ISSN":["2296-861X"],"issn-type":[{"value":"2296-861X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,19]]},"article-number":"1415743"}}