{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:49:48Z","timestamp":1792133388981,"version":"4.4.0"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to explore the correlation between patients with Hashimoto\u2019s thyroiditis and food intolerance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 172 subjects who visited Guangdong Provincial Hospital of Traditional Chinese Medicine between January 2020 and March 2023 were selected and tested for 90 food-specific IgG antibodies. The study group composed 85 individuals diagnosed with Hashimoto\u2019s thyroiditis, while the control group consisted of 87 healthy individuals. Data were analyzed to determine the correlation between Hashimoto\u2019s thyroiditis and food intolerance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 85 patients with Hashimoto\u2019s thyroiditis, 97.65% exhibited food intolerance, with an average of 15.76 \u00b1 10.61 types of food intolerances. The most common intolerances were to eggs (75.29%), bok choy (71.76%), and milk (65.88%), each exceeding a 60% intolerance rate. In the control group of 87 healthy individuals, the intolerance rate was 95.40%, with an average of 9.57 \u00b1 8.90 types of food intolerances. The most prevalent intolerances in the control group were to bok choy (54.02%) and eggs (52.87%), each exceeding a 50% intolerance rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings suggest that patients with Hashimoto\u2019s thyroiditis are more likely to develop food intolerance compared to the healthy population, which may indicate a correlation between Hashimoto\u2019s thyroiditis and food intolerance. Different dietary patterns may affect the activity of the thyroid axis and may even be the cause of autoimmune thyroid disease. The technique of detecting food intolerance IgG antibodies has the potential to be an important reference for dietary interventions in patients with Hashimoto\u2019s thyroiditis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2024.1452371","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:46:31Z","timestamp":1727657191000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Analysis of the correlation between Hashimoto\u2019s thyroiditis and food intolerance"],"prefix":"10.3389","volume":"11","author":[{"given":"Manli","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiyuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiting","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,9,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2024.1361660","article-title":"The impact of gut microbiota on autoimmune thyroiditis and relationship with pregnancy outcomes: a review.","volume":"14","author":"Song","year":"2024","journal-title":"Front Cell Infect Microbiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.13729\/j.issn.1671-7813","article-title":"Clinical effect of wenyang xiaoying formula on Hashimoto\u2019s Thyroiditis and lts influence on TPOAb and TGAb titers.","volume":"38","author":"Wu","year":"2024","journal-title":"J Pract Traditional Chin Int Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1007\/s12020-023-03634-x","article-title":"Transition from Hashimoto thyroiditis to Graves\u2019s disease: an unpredictable change?","volume":"84","author":"Vassallo","year":"2024","journal-title":"Endocrine."},{"key":"B4","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s42000-023-00470-6","article-title":"Patients with Hashimoto\u2019s thyroiditis present higher immune response to COVID-19 mRNA vaccine compared to normal individuals.","volume":"23","author":"Polymeris","year":"2024","journal-title":"Horm Int J Endocrino."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-024-03686-7","article-title":"Analysis of T follicular and T peripheral helper lymphocytes in autoimmune thyroid disease.","author":"S\u00e1nchez-Guti\u00e9rrez","year":"2024","journal-title":"Endocrine."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-024-01304-4","article-title":"Intestinal microbiota regulates the gut-thyroid axis: the new dawn of improving Hashimoto thyroiditis.","volume":"24","author":"Zhu","year":"2024","journal-title":"Clin Exp Med."},{"key":"B7","first-page":"150","article-title":"Food intolerance and related diseases.","volume":"2","author":"Xie","year":"2006","journal-title":"Chin J Internal Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"626\u201330","DOI":"10.3760\/cma.j.issn.1673-4394.2021.06.005","article-title":"Study on the relationship between food specific lgG antibody and Hashimoto\u2019s thyroiditis.","volume":"44","author":"An","year":"2021","journal-title":"Int J Immunol."},{"key":"B9","year":"2008","journal-title":"Chinese Society of Endocrinology, Chinese Society of Medical Sciences, Guidelines for the Diagnosis and Treatment of Thyroid Diseases in China"},{"key":"B10","year":"","journal-title":"Hashimoto\u2019s Thyroiditis (Chronic Lymphocytic Thyroiditis or Autoimmune Thyroiditis."},{"key":"B11","article-title":"The Study on the Relationship Between Food intolerance lgG and Serum Specific lgE in Abdominal type Henoch-Sch\u00f6nleinPurpura in children [D]","author":"Xue","year":"2017"},{"key":"B12","doi-asserted-by":"publisher","first-page":"212","DOI":"10.3969\/j.issn.1008-70.2021.02.029","article-title":"Analysis of serum specific immunoglobulin E and immunoglobulin G in children with allergic purpura.","volume":"56","author":"Zhao","year":"2021","journal-title":"Chin J Med."},{"key":"B13","first-page":"212","article-title":"Detection and analysis of food intolerance in patients with psoriasis.","volume":"31","author":"Wei","year":"2014","journal-title":"Dermatol Bull."},{"key":"B14","author":"Yang","year":"","journal-title":"A Preliminary Study on the Relationship between Systemic Lupus Erythematosus and Food Intolerance. 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