{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:38:49Z","timestamp":1789537129372,"version":"build-2803163510"},"reference-count":74,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Time-restricted eating (TRE), a subtype of intermittent fasting, is increasingly explored as a dietary strategy for weight and metabolic management. However, its effects in overweight and obese women remain unclear. This systematic review and meta-analysis aimed to evaluate the impact of TRE on body composition and metabolic parameters in this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Following PRISMA guidelines and PROSPERO registration (CRD42024595472), randomized controlled trials were retrieved from eight English and Chinese databases up to August 2024. Eligible studies included adult women (\u226585% female, BMI\u202f\u2265\u202f25\u202fkg\/m<jats:sup>2<\/jats:sup>) receiving TRE interventions with or without caloric restriction. Quality was assessed using RoB 2.0 and the PEDro scale. Meta-analyses were conducted using Stata 17.0, with evidence certainty graded using GRADE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirteen RCTs involving 612 participants were included. TRE significantly reduced body weight (WMD\u202f=\u202f\u22121.927\u202fkg, 95% CI: \u22123.688 to \u22120.166, <jats:italic>p<\/jats:italic>\u202f=\u202f0.032) and fasting insulin levels (WMD\u202f=\u202f\u22122.120 \u03bcU\/mL, 95% CI: \u22124.172 to \u22120.069, <jats:italic>p<\/jats:italic>\u202f=\u202f0.043), but showed no significant effects on BMI, fat mass, fat-free mass, visceral fat, blood lipids, glucose, HOMA-IR, or blood pressure (<jats:italic>p<\/jats:italic>\u202f&amp;gt;\u202f0.05). Subgroup analysis revealed greater weight reduction with TRE compared to conventional diets (<jats:italic>p<\/jats:italic>\u202f=\u202f0.046), but not versus calorie restriction alone (<jats:italic>p<\/jats:italic>\u202f=\u202f0.295). No lean mass loss was observed. Four studies reported minor adverse events (e.g., hunger, headache), all self-resolving.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TRE is effective in reducing body weight and lowering fasting insulin in overweight and obese women, without negatively affecting lean body mass. Compared with traditional calorie-restricted diets, TRE does not yield superior weight loss, suggesting comparable efficacy. TRE demonstrates a favorable safety profile and better adherence, supporting its clinical feasibility. Further trials with larger samples and longer follow-up are needed to clarify TRE\u2019s long-term metabolic effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Systematic review registration<\/jats:title><jats:p>The systematic review was registered in PROSPERO. Registration ID: CRD42024595472 URL: <jats:uri>https:\/\/www.crd.york.ac.uk\/prospero\/display_record.php?RecordID=459547<\/jats:uri>.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnut.2025.1664412","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T04:12:41Z","timestamp":1757995961000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Effects of time-restricted eating on body composition and metabolic parameters in overweight and obese women: a systematic review and meta-analysis"],"prefix":"10.3389","volume":"12","author":[{"given":"Shiying","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakub","family":"Kortas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1038\/s41574-019-0176-8","article-title":"Obesity: global epidemiology and pathogenesis","volume":"15","author":"Bl\u00fcher","year":"2019","journal-title":"Nat Rev 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