{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:57:04Z","timestamp":1781585824703,"version":"3.54.5"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hemoglobin (Hb) is an established prognostic biomarker in several conditions, but its prognostic value in elderly patients with dysphagia is unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate whether Hb concentration predicts all-cause mortality in Japanese geriatric patients with dysphagia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We performed a retrospective secondary analysis of a publicly available Japanese cohort (Dryad;\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f253; Jan 2014\u2013Jan 2017). Hemoglobin measured \u22647\u202fdays before nutritional support initiation was analyzed as a continuous variable and by tertiles (T1\u202f&amp;lt;\u202f9\u202fg\/dL; T2 9\u201312\u202fg\/dL; T3\u202f\u2265\u202f12\u202fg\/dL). Cox proportional hazards models estimated associations (Models I\u2013III: unadjusted to fully adjusted). Survival probabilities were assessed by Kaplan\u2013Meier analysis; subgroup interactions were tested.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Median age was 83\u202fyears (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f253; 154 females). In multivariable analysis Hb (per 1\u202fg\/dL) was independently associated with lower mortality (adjusted HR\u202f=\u202f0.83; 95% CI: 0.76\u20130.91;\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). Compared with T1, adjusted HRs were 0.62 (95% CI: 0.41\u20130.93;\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.021) for T2 and 0.36 (95% CI: 0.21\u20130.60;\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001) for T3. Median survival increased across tertiles (T1:185\u202fdays; T2:309\u202fdays; T3:405\u202fdays; log-rank\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). No significant subgroup interactions were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher hemoglobin concentration was independently associated with lower mortality risk in this Japanese cohort of hospitalized geriatric patients with advanced dysphagia requiring artificial nutrition, supporting routine Hb monitoring to inform nutritional and prognostic care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1746775","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:28:09Z","timestamp":1781584089000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Hemoglobin predicts mortality risk in geriatric patients with dysphagia: a Japanese retrospective cohort study"],"prefix":"10.3389","volume":"13","author":[{"given":"Ping","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of General Section I, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People\u2019s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhuo","sequence":"additional","affiliation":[{"name":"Department of General Section I, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People\u2019s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyi","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of General Section I, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People\u2019s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinglin","family":"Gao","sequence":"additional","affiliation":[{"name":"Division I, Department of Geriatric Respiratory, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People\u2019s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/j.mcna.2021.05.013","article-title":"Dysphagia and swallowing disorders","volume":"105","author":"McCarty","year":"2021","journal-title":"Med Clin North Am"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1038\/nrgastro.2015.199","article-title":"Oropharyngeal dysphagia: manifestations and 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