{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:13:14Z","timestamp":1784128394577,"version":"3.55.0"},"reference-count":55,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>A high consumption of ultra-processed foods (UPF) has been associated with higher risk of gastrointestinal cancers, although this relationship has been insufficiently investigated. We evaluated the association between UPF consumption and oesophageal, stomach, and pancreatic cancers in a multi-case control study conducted in a Mediterranean area of Spain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data were analysed for 1,218 participants from the PANESOES study, which included incident cases of oesophageal (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f193), stomach (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f412), and pancreatic (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f161) cancers, and 452 controls. Diet was assessed five years before the interview using validated food frequency questionnaire. UPF consumption was estimated in grams\/day and as a percentage of total dietary intake using the NOVA classification system and then categorised in tertiles. Multinomial logistic regression was applied to estimate relative risk ratios (RRR) and 95% confidence intervals (CI) adjusting for potential confounders.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>UPF consumption in grams\/day was positively associated with oesophageal and stomach cancers. Compared with the lowest tertile, the highest tertile of UPF consumption was associated with higher risk of oesophageal cancer (RRR\u202f=\u202f2.29; 95% CI: 1.37\u20133.82) and stomach cancer (RRR\u202f=\u202f1.56; 95% CI: 1.08\u20132.27). For stomach cancer, the highest consumption of ultra-processed dairy products (RRR\u202f=\u202f2.10; 95% CI: 1.43\u20132.82) and sweets\/pastries (RRR\u202f=\u202f1.76; 95% CI: 1.24\u20132.50) showed increased risks. Ultra-processed drinks and pre-cooked foods were associated with higher risk of oesophageal cancer. No associations were observed for pancreatic cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Higher UPF consumption was associated with increased risk of oesophageal and stomach cancers, particularly linked to specific UPF categories. Further research is recommended to confirm these results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1764868","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T05:29:48Z","timestamp":1772083788000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultra-processed food consumption and risk of oesophagus, stomach, and pancreatic cancers: a multi case\u2013control study"],"prefix":"10.3389","volume":"13","author":[{"given":"Laura","family":"Torres-Collado","sequence":"first","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Instituto de Salud Carlos III","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Gonz\u00e1lez-Palacios","sequence":"additional","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Instituto de Salud Carlos III","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Mar\u00eda","family":"Compa\u00f1-Gabucio","sequence":"additional","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Instituto de Salud Carlos III","place":["Madrid, Spain"]},{"name":"Departamento de Patolog\u00eda y Cirug\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Ojeda-Belokon","sequence":"additional","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Instituto de Salud Carlos III","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marielisa Gabriela","family":"Belisario-Ubeto","sequence":"additional","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Garc\u00eda-de-la-Hera","sequence":"additional","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Instituto de Salud Carlos III","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Oncina-C\u00e1novas","sequence":"additional","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Instituto de Salud Carlos III","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Vioque","sequence":"additional","affiliation":[{"name":"Unidad de Epidemiolog\u00eda de la Nutrici\u00f3n, Departamento de Salud P\u00fablica, Historia de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez (UMH)","place":["Alicante, Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria y Biom\u00e9dica de Alicante (ISABIAL), Departamento de Salud P\u00fablica, H\u00aa de la Ciencia y Ginecolog\u00eda, Universidad Miguel Hern\u00e1ndez","place":["Alicante, Spain"]},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP), Instituto de Salud Carlos III","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA A Cancer J Clinicians"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"100845","DOI":"10.1016\/j.ctarc.2024.100845","article-title":"Gastric cancer-epidemiology, modifiable and non-modifiable risk factors, challenges and opportunities: an updated review","volume":"41","author":"Mamun","year":"2024","journal-title":"Cancer Treat Res 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Epinut \u2013 Universidad Miguel Hern\u00e1ndez","year":"1991"},{"key":"ref33","first-page":"2039","article-title":"A new classification of foods based on the extent and purpose of their processing","volume-title":"Cad Saude Publica","author":"Monteiro","year":"2010"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"e077310","DOI":"10.1136\/bmj-2023-077310","article-title":"Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses","volume":"384","author":"Lane","year":"2024","journal-title":"BMJ"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/j.ajcnut.2024.06.010","article-title":"Associations of ultraprocessed food consumption with mortality among participants with a history of cancer: a prospective cohort analysis","volume":"120","author":"Zhao","year":"2024","journal-title":"Am J Clin 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