{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:06:33Z","timestamp":1784304393615,"version":"3.55.0"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Obesity and low handgrip strength (HGS) have both been associated with cognitive impairment and dementia, but their combined association remains unclear. This study examined the association of obesity and low HGS, separately and jointly, with cognitive impairment and probable dementia in older Colombian adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A secondary cross-sectional analysis was conducted using data from the Colombian Health, Well-Being, and Aging Survey (SABE Colombia 2015). The analytic sample included 4,656 community-dwelling adults aged \u226560 years. Obesity was defined as body mass index \u226530 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , and low HGS was defined using EWGSOP2 sex-specific cut-off points (&amp;lt;27 kg for men and &amp;lt;16 kg for women). Cognitive impairment was assessed using a revised version of the Mini-Mental State Examination. Probable dementia was defined as the co-occurrence of cognitive impairment and at least two limitations in instrumental activities of daily living.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Cognitive impairment was present in 12.2% of men and 14.2% of women, while probable dementia was observed in 4.9% of men and 6.6% of women. Low HGS, with or without obesity, was associated with higher odds of cognitive impairment in both sexes. For probable dementia, low HGS was associated with higher odds in both sexes, whereas obesity combined with low HGS was significantly associated with probable dementia only in women in the fully adjusted model. Obesity with normal HGS was not associated with either outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Low HGS, rather than obesity alone, was associated with cognitive impairment and probable dementia in Colombian older adults. These findings support the relevance of considering muscular function when examining cognitive health in later life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1813754","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T15:39:41Z","timestamp":1784302781000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["The joint association of obesity and low handgrip strength with cognitive impairment and probable dementia: a cross-sectional study"],"prefix":"10.3389","volume":"13","author":[{"given":"Robinson","family":"Ram\u00edrez-V\u00e9lez","sequence":"first","affiliation":[{"name":"Navarrabiomed, IdiSNA, Hospital Universitario de Navarra (HUN), Universidad P\u00fablica de Navarra (UPNA)","place":["Pamplona, Spain"]},{"name":"CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III","place":["Madrid, Spain"]},{"name":"Facultad de Ciencias de la Educaci\u00f3n, Unidad Central del Valle del Cauca (UCEVA)","place":["Tulu\u00e1, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel Germ\u00e1n","family":"Borda","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cl\u00ednica Universidad de Navarra","place":["Pamplona, Spain"]},{"name":"Centre for Age-Related Medicine (SESAM), Stavanger University Hospital","place":["Stavanger, Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Calder\u00f3n-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Educaci\u00f3n, Unidad Central del Valle del Cauca (UCEVA)","place":["Tulu\u00e1, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Romero-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Educaci\u00f3n, Unidad Central del Valle del Cauca (UCEVA)","place":["Tulu\u00e1, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikel","family":"Izquierdo","sequence":"additional","affiliation":[{"name":"Navarrabiomed, IdiSNA, Hospital Universitario de Navarra (HUN), Universidad P\u00fablica de Navarra (UPNA)","place":["Pamplona, Spain"]},{"name":"CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III","place":["Madrid, Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"P\u00e9rez-Sousa","sequence":"additional","affiliation":[{"name":"Department of Physical Education, Faculty of Education, University of C\u00f3rdoba","place":["Cordoba, Spain"]},{"name":"Epidemiology of Physical Activity and Fitness across Lifespan Research Group, University of Seville","place":["Seville, 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