{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T04:51:22Z","timestamp":1782449482247,"version":"3.54.5"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess associations of maternal pre-pregnancy BMI with pregnancy complications, adverse perinatal outcomes, and infant adiposity at 6 months corrected age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This two-center retrospective cohort included 707 mother-infant dyads from 790 eligible pregnancies between March 2021 and June 2023. Pre-pregnancy BMI was classified as underweight (&amp;lt;18.5 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), normal-weight (18.5\u201323.9 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), overweight (24.0\u201327.9 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), and obesity (\u226528.0 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). Infant anthropometry at 6 months corrected age was converted to WHO z-scores. Multivariable logistic regression was used to explore factors associated with adverse perinatal outcomes and infant obesity at 6 months corrected age.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 707 women, 47 (6.6%) were underweight, 314 (44.4%) normal-weight, 220 (31.1%) overweight, and 126 (17.8%) obese. Higher BMI category was associated with higher HbA1c, gestational diabetes mellitus, gestational hypertensive disorders, postpartum hemorrhage, macrosomia, NICU admission, and infant adiposity z-scores. Compared with normal weight, overweight (adjusted OR 1.38, 95% CI 1.01\u20131.90) and obesity (adjusted OR 1.86, 95% CI 1.24\u20132.78) were associated with higher odds of adverse perinatal outcomes. Maternal obesity was associated with higher odds of infant obesity at 6 months corrected age (adjusted OR 2.23, 95% CI 1.18\u20134.20), whereas breastfeeding was associated with lower odds (adjusted OR 0.65, 95% CI 0.39\u20130.94).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Maternal pre-pregnancy overweight and obesity were associated with pregnancy complications, adverse perinatal outcomes, and increased infant adiposity at 6 months corrected age. Preconception weight management and breastfeeding support may help reduce early metabolic risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1820970","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T04:39:39Z","timestamp":1782448779000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations of maternal pre-pregnancy body mass index with pregnancy complications and infant adiposity at 6 months corrected age: a two-center retrospective cohort study"],"prefix":"10.3389","volume":"13","author":[{"given":"Rong","family":"Zeng","sequence":"first","affiliation":[{"name":"Chengdu Wenjiang Maternal and Child Health Hospital","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Yuan","sequence":"additional","affiliation":[{"name":"Bazhong Maternal and Child Health Hospital, Bazhong","place":["Sichuan, 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