{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:46:43Z","timestamp":1785818803553,"version":"3.56.0"},"reference-count":42,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Daily dietary patterns are associated with\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                      (Hp) infection, though with notable regional differences. However, their impact on Hp eradication efficacy and treatment-related adverse events remains unclear.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This two-part observational study assessed the link between diet and Hp. A cross-sectional analysis (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f464 after matching) identified dietary patterns associated with infection, and a prospective cohort (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f476) evaluated how these patterns influenced eradication rates and adverse events. Dietary patterns were derived via exploratory factor analysis (EFA), with logistic regression and restricted cubic splines used to analyze associations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In the cross-sectional phase, a \u201ctraditional northwest\u201d pattern increased infection risk (OR\u202f=\u202f3.776, 95% CI 2.099\u20136.792), while a \u201cplant-based\u201d pattern reduced it (OR\u202f=\u202f0.479, 95% CI 0.268\u20130.856). In the prospective cohort, the overall eradication rate was 88.7%. None of the identified dietary patterns (high-protein, traditional northwest, or healthy) showed a significant association with eradication rates. However, adverse events occurred in 20.4% of participants during eradication therapy, with bitter taste being most common (32.0%). The traditional northwest pattern, characterized by high-salt diet, was associated with a reduced risk of these events (OR\u202f=\u202f0.396, 95% CI 0.188\u20130.837).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Daily dietary patterns were associated with Hp infection and eradication-related adverse events, but not eradication rate. These findings suggest that dietary patterns may be applicable to Hp prevention and management strategies, independent of their influence on eradication efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1821481","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:27:50Z","timestamp":1785817670000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Daily dietary patterns associated with Helicobacter pylori infection and eradication-related adverse events, but not eradication rate: a cross-sectional and prospective cohort study"],"prefix":"10.3389","volume":"13","author":[{"given":"Huan","family":"Zhang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University","place":["Xi\u2019an, China"]},{"name":"Department of Gastroenterology, The 961th Hospital of Joint Logistics Support Force of PLA","place":["Qiqihar, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qimeng","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, 3201 Hospital","place":["Hanzhong, Shaanxi, China"]},{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University","place":["Xi\u2019an, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nannan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The 961th Hospital of Joint Logistics Support Force of PLA","place":["Qiqihar, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jumei","family":"Yin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University","place":["Xi\u2019an, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University","place":["Xi\u2019an, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University","place":["Xi\u2019an, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Shang","sequence":"additional","affiliation":[{"name":"Department of Health Statistics, School of Preventive Medicine, Fourth Military Medical University","place":["Xi'an, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongquan","family":"Shi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University","place":["Xi\u2019an, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheyi","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Air Force Medical Center, Fourth Military Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1097\/MCG.0000000000001719","article-title":"Helicobacter pylori world gastroenterology organization global guideline","volume":"57","author":"Katelaris","year":"2023","journal-title":"J Clin Gastroenterol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1724","DOI":"10.1136\/gutjnl-2022-327745","article-title":"Management of Helicobacter pylori infection: the Maastricht VI\/Florence consensus report","volume":"71","author":"Malfertheiner","year":"2022","journal-title":"Gut"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"875","DOI":"10.3390\/pathogens10070875","article-title":"Impact of dietary patterns on H. pylori infection and the modulation of microbiota to counteract its effect. 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