{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:51:11Z","timestamp":1777492271371,"version":"3.51.4"},"reference-count":175,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:p>Plant-based diets have gained considerable interest in recent times due to their perceived health and environmental benefits. However, the term \u201cplant-based diet\u201d refers to a broad range of diets with a wide range of differences in food quality and nutritional content. This article aims to summarize the available evidence regarding the health and environmental impacts of plant-based diets, including new trends and issues. Epidemiological studies, RCTs, and life cycle assessment studies were searched in various scientific databases to investigate the relationship between plant-based diets and various health outcomes or environmental impacts. Available evidence from prospective studies and RCTs suggests that well-planned plant-based diets are associated with a lower risk of cardiometabolic diseases and beneficial alterations in the gut microbiome. Environmental studies have uniformly found lower greenhouse gas emissions, land use, and water use associated with a human diet compared with an animal-based diet; however, the extent of these positive impacts depends on the diet composition. On the other hand, nutrient adequacy such as iron, vitamin B12, omega-3 fatty acids, processing, and socio-economic factors are also important considerations. This review aims at an integrated approach in environmental sustainability viewpoints with health results, comprehensive understanding the relationship between the quality of diet and health outcomes in the context of a circular food system and research priorities in guiding future diets.<\/jats:p>","DOI":"10.3389\/fnut.2026.1830797","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:51:37Z","timestamp":1777387897000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Plant-based diets for human health with implications for cardiometabolic health, gut microbiome, and nutritional adequacy"],"prefix":"10.3389","volume":"13","author":[{"given":"Mansour","family":"Alblaji","sequence":"first","affiliation":[{"name":"Department of Basic Health Sciences, College of Applied Medical Sciences, Qassim University","place":["Buraydah, Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"19003","DOI":"10.1186\/s12889-024-19003-w","article-title":"Nutrient deficiency patterns and all-cause and cardiovascular mortality in older adults with hypertension: a latent class analysis","volume":"24","author":"Sun","year":"2024","journal-title":"BMC Public Health"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"10121","DOI":"10.1073\/pnas.2319010121","article-title":"A multicriteria analysis of meat and milk alternatives from nutritional, health, environmental, and cost perspectives","volume":"121","author":"Springmann","year":"2024","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"7766","DOI":"10.1177\/15598276241237766","article-title":"Health benefits of a plant-based dietary pattern and implementation in healthcare and clinical practice","volume":"18","author":"Landry","year":"2024","journal-title":"Am J Lifestyle Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"6473","DOI":"10.1007\/s11357-024-01262-5.pdf","article-title":"Coffee consumption and cardiometabolic health: a comprehensive review of the evidence","volume":"46","author":"Ungv\u00e1ri","year":"2024","journal-title":"Geroscience"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1186\/s40100-025-00359-5","article-title":"Acceptability of meat tax and subsidy removal by meat eaters: insights from five European countries","volume":"13","author":"Kme\u0165kov\u00e1","year":"2025","journal-title":"Agric Food Econ"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.25081\/IA.2023-030","article-title":"Plant-based dairy substitutes: current scenario and future prospects","volume":"6","author":"Khaliq","year":"2023","journal-title":"Innov. 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Nutr."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"e70373","DOI":"10.1002\/fsn3.70373","article-title":"Exploring the effects of novel food processing methods on food proteins: a review","volume":"13","author":"Wei","year":"2025","journal-title":"Food Sci Nutr"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"3834","DOI":"10.1007\/s00203-024-03834-7","article-title":"Butyrate\u2019s (a short-chain fatty acid) microbial synthesis, absorption, and preventive roles against colorectal and lung cancer","volume":"206","author":"Karim","year":"2024","journal-title":"Arch Microbiol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1007\/s12672-024-01313-5","article-title":"Short-chain fatty acids play a positive role in colorectal cancer","volume":"15","author":"Liu","year":"2024","journal-title":"Discov Oncol"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s43440-026-00823-z","article-title":"Exploring the anti-inflammatory activity of sulforaphane metabolites","volume":"22","author":"Pagliarani","year":"2026","journal-title":"Pharmacol. Rep."},{"key":"ref53","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1186\/s12916-025-04440-0","article-title":"Lycopene intake and prostate cancer risk in men at high cardiovascular risk: a prospective cohort study","volume":"23","author":"L\u00f3pez-Sol\u00eds","year":"2025","journal-title":"BMC Med."},{"key":"ref54","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1007\/s13237-024-00503-4","article-title":"Plant flavonol quercetin engenders cytotoxic effect in different pre-clinical cancer models through modulation of diverse epigenetic regulators","volume":"68","author":"Ganai","year":"2024","journal-title":"Nucleus"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s12263-018-0594-6","article-title":"Studying microbial functionality within the gut ecosystem by systems biology","volume":"13","author":"Hornung","year":"2018","journal-title":"Genes Nutr."},{"key":"ref56","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1080\/19490976.2021.1907270","article-title":"From taxonomy to metabolic output: what factors define gut microbiome health?","volume":"13","author":"Wilmanski","year":"2021","journal-title":"Gut Microbes"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"4016","DOI":"10.3934\/microbiol.2024016","article-title":"Why does increased microbial fermentation in the human colon shift toward butyrate?","volume":"10","author":"Flint","year":"2024","journal-title":"AIMS Microbiol"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s12967-025-07428-9","article-title":"Dietary interventions and the gut microbiota: a systematic literature review of 80 controlled clinical trials","volume":"24","author":"Aslam","year":"2026","journal-title":"J Transl Med"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1007\/s13668-021-00387-9","article-title":"The influence of animal- or plant-based diets on blood and urine trimethylamine-N-oxide (TMAO) levels in humans","volume":"11","author":"Lombardo","year":"2022","journal-title":"Curr Nutr Rep"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"2499","DOI":"10.1007\/s00204-023-03562-9","article-title":"Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging","volume":"97","author":"Jomov\u00e1","year":"2023","journal-title":"Archives Toxicol."},{"key":"ref61","doi-asserted-by":"crossref","first-page":"287","DOI":"10.4018\/979-8-3373-3982-5.ch009","volume-title":"Detection, Identification, and Monitoring of Food Contaminants","author":"Ogidi","year":"2025"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"e70350","DOI":"10.1111\/1541-4337.70350","article-title":"Recent advances in lemongrass essential oil: food safety, preservation, and bioactivity in food systems","volume":"25","author":"Rabbani","year":"2026","journal-title":"Compr Rev Food Sci Food Saf"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1161\/JAHA.118.011367","article-title":"Anti-inflammatory effects of a vegan diet versus the American Heart Association\u2013recommended diet in coronary artery disease trial","volume":"7","author":"Shah","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"809","DOI":"10.2174\/1573407215666190419205317","article-title":"Anti-inflammatory plant polyphenolics and cellular action mechanisms","volume":"16","author":"Mir","year":"2019","journal-title":"Curr. 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Metab."},{"key":"ref68","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1007\/s00204-024-03696-4","article-title":"Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants","volume":"98","author":"Jomov\u00e1","year":"2024","journal-title":"Archives Toxicol."},{"key":"ref69","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4018\/979-8-3693-9869-2.ch004","volume-title":"Nanocarriers in Plant Science and Agriculture","author":"Ogidi","year":"2025"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1186\/s12964-022-00906-3","article-title":"An update of Nrf2 activators and inhibitors in cancer prevention\/promotion","volume":"20","author":"Pouremamali","year":"2022","journal-title":"Cell Commun Signal"},{"key":"ref71","doi-asserted-by":"publisher","first-page":"12009","DOI":"10.1002\/jimd.12009","article-title":"Vitamin B12, folate, and the methionine remethylation cycle\u2014biochemistry, pathways, and regulation","volume":"42","author":"Froese","year":"2019","journal-title":"J Inherit Metab Dis"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"2333","DOI":"10.1177\/03795721241227233","article-title":"Vitamin B12 status and supplementation in plant-based diets","volume":"45","author":"Hannibal","year":"2024","journal-title":"Food Nutr Bull"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"S40","DOI":"10.1177\/03795721241229500","article-title":"A brief overview of the diagnosis and treatment of cobalamin (B12) deficiency","volume":"45","author":"Wolffenbuttel","year":"2024","journal-title":"Food Nutr. 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