{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T08:05:16Z","timestamp":1784102716086,"version":"3.55.0"},"reference-count":44,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:p>\n                    Combat sports athletes frequently experience gastrointestinal disturbances during pre-competition weight management. This study aimed to investigate the effects of probiotic supplementation on gut barrier function in combat athletes undergoing rapid weight loss prior to competition. Twenty-four elite male athletes were randomized to receive either a complex sports probiotic (1.5\u202f\u00d7\u202f10\n                    <jats:sup>10<\/jats:sup>\n                    CFU, twice daily) or placebo for 4 weeks. Results showed that probiotic supplementation significantly reduced gastrointestinal symptoms and gut permeability markers (Zonulin, intestinal fatty acid-binding protein, D-lactate), increased secretory immunoglobulin A (SIgA) levels, and attenuated systemic inflammation compared to placebo. The intervention enriched beneficial butyrate-producing bacteria (\n                    <jats:italic>Blautia<\/jats:italic>\n                    ,\n                    <jats:italic>Latilactobacillus<\/jats:italic>\n                    ) while suppressing pathogenic\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    . These findings demonstrate that probiotic supplementation serves as a safe, effective nutritional strategy to maintain gut homeostasis during rapid weight loss in combat athletes.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>http:\/\/www.chictr.org.cn<\/jats:ext-link>\n                      , identifier ChiCTR2400079908.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1857878","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T07:11:37Z","timestamp":1784099497000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of probiotic supplementation on gut barrier function in combat athletes during pre-competition weight loss"],"prefix":"10.3389","volume":"13","author":[{"given":"Jing","family":"Wang","sequence":"first","affiliation":[{"name":"School of Exercise and Health, Shanghai University of Sport","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-yi","family":"Lai","sequence":"additional","affiliation":[{"name":"School of Exercise and Health, Shanghai University of Sport","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-jiao","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Exercise and Health, Shanghai University of Sport","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-qin","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Exercise and Health, Shanghai University of Sport","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-ting","family":"Shen","sequence":"additional","affiliation":[{"name":"School of Exercise and Health, Shanghai University of Sport","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qun","family":"Zuo","sequence":"additional","affiliation":[{"name":"School of Athletic Performance, Shanghai University of Sport","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1123\/ijspp.2021-0104","article-title":"Effects of weight cutting on exercise performance in combat athletes: a meta-analysis","volume":"17","author":"Brechney","year":"2022","journal-title":"Int J Sports Physiol 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