{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:02:05Z","timestamp":1790226125020,"version":"4.1.0"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Detecting malnutrition in patients with ulcerative colitis is considered a clinical challenge. The Global Leadership Initiative on Malnutrition (GLIM) criteria constitute a standardized approach for diagnosis. However, the Controlling Nutritional Status (CONUT) score is a simple tool based on laboratory analysis; its performance in early malnutrition detection could be improved. Our aim was to exploratorily derive and assess the apparent diagnostic performance of enhanced CONUT-based scores (eCONUT-UC) for identifying GLIM-defined malnutrition in patients with ulcerative colitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross-sectional study in patients with ulcerative colitis. We measured weight, height, body mass index, and body composition using DXA and BIA. We extracted recent laboratory results and clinical data from medical records. We used the GLIM criteria as the reference standard for detecting malnutrition in ulcerative colitis. We evaluated the diagnostic performance of the eCONUT-UC by incorporating phase angle (PhA), hemoglobin (Hgb), and triglycerides (TG). We calculated sensitivity, specificity, and area under the curve (AUC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 51 patients, of whom 15 (29%) met GLIM criteria for malnutrition. The original CONUT score had a sensitivity of 73% and a specificity of 67%. The eCONUT-UC-PhA and eCONUT-UC-Hgb showed a sensitivity of 80%, with an AUC of 0.741 [95% CI: 0.587\u20130.895] and 0.738 [95% CI: 0.586\u20130.890]. The eCONUT-UC-TG showed lower diagnostic performance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The eCONUT-UC showed higher sensitivity in detecting malnutrition than the original CONUT. Its use as a rapid and accessible screening tool supports its potential implementation in clinical practice, particularly in resource-limited settings, to facilitate timely nutritional intervention for patients with ulcerative colitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1907895","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:33:49Z","timestamp":1790224429000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["eCONUT-UC for nutritional screening and malnutrition identification in ulcerative colitis"],"prefix":"10.3389","volume":"13","author":[{"given":"Viridiana Montsserrat","family":"Mendoza-Mart\u00ednez","sequence":"first","affiliation":[{"name":"Proteomics and Metabolomics Laboratory, Research Division","place":["Hospital General de M\u00e9xico \u201cDr. Eduardo Liceaga\u201d Mexico City, Mexico"]},{"name":"Faculty of Medicine, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM)","place":["Mexico City, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desiree","family":"L\u00f3pez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Research Unit, Hospital Infantil de M\u00e9xico Federico G\u00f3mez","place":["Mexico City, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Clark","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Research Unit, Hospital Infantil de M\u00e9xico Federico G\u00f3mez","place":["Mexico City, Mexico"]},{"name":"Secretary of the General Health Council","place":["Mexico City, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Luis","family":"De-Le\u00f3n-Rend\u00f3n","sequence":"additional","affiliation":[{"name":"Inflammatory Bowel Disease Clinic, Coloproctology Service of Hospital General de M\u00e9xico \u201cDr. Eduardo Liceaga\u201d","place":["Mexico City, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto","family":"Roldan-Valadez","sequence":"additional","affiliation":[{"name":"Division of Research, Instituto Nacional de Rehabilitaci\u00f3n Luis Guillermo Ibarra Ibarra","place":["Mexico City, Mexico"]},{"name":"Department of Radiology, I.M. 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