{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:25:15Z","timestamp":1787934315124,"version":"build-2784847793"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dietary phytochemicals have been suggested to play a protective role against cancer development. This study aimed to examine the association between dietary phytochemical index (DPI) and epithelial ovarian cancer (EOC) risk among Chinese women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective case\u2013control study, 500 women (250 newly diagnosed EOC patients and 250 cancer-free participants) were included. Dietary intake was assessed using a validated food frequency questionnaire (FFQ), and DPI was calculated as the percentage of energy derived from phytochemical-rich foods. Multivariable logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between DPI and EOC risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Higher DPI was significantly associated with lower odds of EOC. Each one-unit increase in DPI was linked to a reduced risk in both crude and adjusted models (fully adjusted OR: 0.90; 95% CI: 0.81\u20130.99). Participants in the highest DPI tertile had a 31% lower odds of EOC compared to those in the lowest tertile (OR: 0.69; 95% CI: 0.49\u20130.96). The inverse association was more pronounced among overweight\/obese women (\n                      <jats:italic>P<\/jats:italic>\n                      for interaction\u202f=\u202f0.041).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Greater adherence to a phytochemical-rich diet may be associated with reduced risk of EOC. Prospective studies are warranted to confirm these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1915090","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T15:39:08Z","timestamp":1787931548000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Higher dietary phytochemical index is associated with lower risk of epithelial ovarian cancer in Chinese women: a case\u2013control study"],"prefix":"10.3389","volume":"13","author":[{"given":"Yu\u2019e","family":"Yang","sequence":"first","affiliation":[{"name":"First Clinical Medical School of Gansu University of Chinese Medicine","place":["Lanzhou, Gansu, China"]},{"name":"The First Clinical Medical College of Ningxia Medical University","place":["Yinchuan, Ningxia Hui Autonomous Region, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College of Ningxia Medical University","place":["Yinchuan, Ningxia Hui Autonomous Region, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengwei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine, The Second Affiliated Hospital of Fujian Medical University","place":["Quanzhou, Fujian, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizheng","family":"Zu","sequence":"additional","affiliation":[{"name":"Department of Gynecology, The Second People\u2019s Hospital of Changzhou, The Third Affiliated Hospital of Nanjing Medical University","place":["Changzhou, Jiangsu, 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