{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:59:24Z","timestamp":1790657964780,"version":"4.1.0"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Food safety complaint systems contain large numbers of heterogeneous adverse-event reports, but surveillance use requires reproducible data sources and interpretable rules for ranking reports that may involve severe outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To construct and test a transparent case-level logistic triage model that assigns FDA Human Foods Complaint System (HFCS) reports an urgent-priority score for earlier human review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The official HFCS quarterly workbook was downloaded from the FDA website on 2026-05-13, and case-based reports received from January 1, 2004 through December 31, 2025 were analyzed (\n                      <jats:italic>n<\/jats:italic>\n                      = 149,642). Predictors were derived from validated age and date fields, sex, suspected product descriptors, MedDRA preferred-term counts, symptom-domain indicators, report year, and event-to-receipt lag. Product-group proportions were summarized with unadjusted Wilson 95% confidence intervals and interpreted descriptively. A balanced logistic regression model was assessed on a stratified test set.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Urgent-priority outcomes occurred in 47,093 reports (31.47%). Death appeared in 17,005 reports and hospitalization in 23,405. The hospitalization proportion was 24.9% (95% CI, 24.5\u201325.3%) among dietary-supplement reports and 18.2% (16.3\u201320.3%) among infant\/baby-food reports; these unadjusted proportions were not interpreted as population risk differences. The model achieved an AUC of 0.723, PR-AUC of 0.526, Brier score of 0.214, Brier skill score of 0.008, a calibration intercept of \u22120.03, and a calibration slope of 0.91 on 37,411 test cases. Symptom count and the infant\/baby-food indicator had the largest positive model weights.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HFCS data can support reproducible complaint triage. The model is suitable for ordering reports for human review, whereas product-group contrasts and raw predicted probabilities require cautious interpretation and temporal or external validation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnut.2026.1919174","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:37:58Z","timestamp":1790656678000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Construction and empirical testing of a verifiable food safety complaint risk-triage model using human foods complaint system data from the United States Food and Drug Administration"],"prefix":"10.3389","volume":"13","author":[{"given":"Jinming","family":"Chen","sequence":"first","affiliation":[{"name":"College of Food Science and Engineering, Shanxi Agricultural University","place":["Taigu, Shanxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"ref1","year":"2025"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3201\/eid1701.p11101","article-title":"Foodborne illness acquired in the United States--major pathogens","volume":"17","author":"Scallan","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"ref3","year":"2024"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e1001923","DOI":"10.1371\/journal.pmed.1001923","article-title":"World Health Organization global estimates and regional comparisons of the burden of foodborne disease in 2010","volume":"12","author":"Havelaar","year":"2015","journal-title":"PLoS Med"},{"key":"ref5","year":"2024"},{"key":"ref6","volume-title":"Food and Agriculture Organization of the United Nations. 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