{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:21:24Z","timestamp":1788452484111,"version":"build-2803163510"},"reference-count":53,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010609","name":"Medical University of Gda\u0144sk","doi-asserted-by":"publisher","award":["01-10026\/0010396\/01\/221\/221\/0\/2026"],"award-info":[{"award-number":["01-10026\/0010396\/01\/221\/221\/0\/2026"]}],"id":[{"id":"10.13039\/501100010609","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nutr."],"abstract":"<jats:p>Treatment-resistant depression (TRD) is associated with persistent symptoms, impaired functioning, physical comorbidity and a high risk of recurrence, making continuation and maintenance care particularly important. Nutrition may influence several modifiable aspects of recovery, including cardiometabolic health, daily functioning, self-care and treatment adherence, although evidence for a direct effect on depressive recurrence remains limited. This review examines the role of nutritional care within TRD relapse prevention, with particular attention to psychiatric nursing practise. Available dietary intervention studies in depression suggest potential benefits for depressive symptoms and broader health outcomes, but most have focused on acute treatment rather than recurrence or maintenance, and data specific to TRD remain sparse. Evidence for nurse-delivered nutritional interventions is also limited, although studies in broader psychiatric populations indicate that dietary assessment, education, behavioural support and follow-up can be incorporated into mental health care. In TRD, psychiatric nurses may contribute through nutritional risk screening, monitoring of appetite, intake, weight and physical health, reinforcement of agreed dietary recommendations, and coordination of specialist referral. Clear professional boundaries are required when malnutrition, eating disorders, refeeding risk, therapeutic diets or clinically significant nutrient\u2013drug interactions are present. Nutritional care should therefore be regarded as an adjunct to established TRD treatment and integrated into multidisciplinary continuation and relapse-prevention care rather than used as a stand-alone intervention.<\/jats:p>","DOI":"10.3389\/fnut.2026.1961751","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T15:47:48Z","timestamp":1788450468000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["The role of psychiatric nurses in nutritional care for treatment-resistant depression: a relapse-prevention perspective"],"prefix":"10.3389","volume":"13","author":[{"given":"Agnieszka","family":"Mechli\u0144ska","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine, Medical University of Gda\u0144sk","place":["Gda\u0144sk, Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Sudo\u0142","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, UCC Gda\u0144sk","place":["Gda\u0144sk, Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota","family":"Pazda-Juda","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine, Medical University of Gda\u0144sk","place":["Gda\u0144sk, Poland"]},{"name":"Department of Psychiatry, UCC Gda\u0144sk","place":["Gda\u0144sk, Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wies\u0142aw Jerzy","family":"Cuba\u0142a","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Faculty of Medicine, Medical University of Gda\u0144sk","place":["Gda\u0144sk, Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1038\/s41380-021-01381-x","article-title":"A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials","volume":"27","author":"Sforzini","year":"2022","journal-title":"Mol Psychiatry"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1002\/wps.21120","article-title":"Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions","volume":"22","author":"McIntyre","year":"2023","journal-title":"World Psychiatry"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1080\/15622975.2020.1851052","article-title":"A clinical approach to treatment resistance in depressed patients: what to do when the usual treatments do not work well enough?","volume":"22","author":"Dodd","year":"2021","journal-title":"World J Biol Psychiatry"},{"key":"ref4","first-page":"1","article-title":"Treatment-resistant depression: diagnosis and treatment. 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