{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T07:58:25Z","timestamp":1789891105707,"version":"4.0.1"},"reference-count":71,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T00:00:00Z","timestamp":1528848000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"DOI":"10.3389\/fonc.2018.00151","type":"journal-article","created":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T04:21:19Z","timestamp":1528863679000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Cancer Incidence in Europe: An Ecological Analysis of Nutritional and Other Environmental Factors"],"prefix":"10.3389","volume":"8","author":[{"given":"Pavel","family":"Grasgruber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Hrazdira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Sebera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Kalina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,6,13]]},"reference":[{"key":"B1","first-page":"60","article-title":"Reproducibility and validity of a short food questionnaire for the assessment of dietary habits","volume":"12","author":"Svilaas","year":"2002","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"B2","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1016\/j.mayocp.2015.04.009","article-title":"The inadmissibility of what we eat in America and NHANES dietary data in nutrition and obesity research and the scientific formulation of national dietary guidelines","volume":"90","author":"Archer","year":"2015","journal-title":"Mayo Clin Proc"},{"key":"B3","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1017\/S002966510800712X","article-title":"The Second World Cancer Research Fund\/American Institute for Cancer Research Expert Report. Food, nutrition, physical activity, and the prevention of cancer: a Global Perspective: Nutrition Society and BAPEN Medical Symposium on \u2018Nutrition support in cancer therapy\u2019","volume":"67","author":"Wiseman","year":"2008","journal-title":"Proc Nutr Soc"},{"key":"B4","volume-title":"Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective","year":"2007"},{"key":"B5","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1743-7075-11-30","article-title":"Prostate cancer and the influence of dietary factors and supplements: a systematic review","volume":"11","author":"Mandair","year":"2014","journal-title":"Nutr Metab (Lond)"},{"key":"B6","first-page":"6861","article-title":"The role of dietary factors in prevention and progression of breast cancer","volume":"34","author":"Rossi","year":"2014","journal-title":"Anticancer Res"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1093\/annonc\/mdx171","article-title":"Foods and beverages and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, an update of the evidence of the WCRF-AICR Continuous Update Project","volume":"28","author":"Vieira","year":"2017","journal-title":"Ann Oncol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.cmet.2014.02.006","article-title":"Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population","volume":"19","author":"Levine","year":"2014","journal-title":"Cell Metab"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.1093\/ije\/dys086","article-title":"Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis","volume":"41","year":"2012","journal-title":"Int J Epidemiol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/S2213-8587(15)00474-X","article-title":"Divergent associations of height with cardiometabolic disease and cancer: epidemiology, pathophysiology, and global implications","volume":"4","author":"Stefan","year":"2016","journal-title":"Lancet Diabetes Endocrinol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/j.coph.2012.07.006","article-title":"Cholesterol and prostate cancer","volume":"12","author":"Pelton","year":"2012","journal-title":"Curr Opin Pharmacol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3389\/fphar.2013.00119","article-title":"The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics","volume":"4","author":"Cruz","year":"2013","journal-title":"Front Pharmacol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.3892\/ol.2010.169","article-title":"Insulin-like growth factor-1 and childhood cancer risk","volume":"1","author":"BaDr","year":"2010","journal-title":"Oncol Lett"},{"key":"B14","unstructured":""},{"key":"B15","unstructured":""},{"key":"B16","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.ehb.2016.01.005","article-title":"Major correlates of male height: a study of 105 countries","volume":"21","author":"Grasgruber","year":"2016","journal-title":"Econ Hum Biol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"31694","DOI":"10.3402\/fnr.v60.31694","article-title":"Food consumption and the actual statistics of cardiovascular diseases: an epidemiological comparison of 42 European countries","volume":"60","author":"Grasgruber","year":"2016","journal-title":"Food Nutr Res"},{"key":"B18","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.eururo.2003.08.018","article-title":"A multicountry ecologic study of risk and risk reduction factors for prostate cancer mortality","volume":"45","author":"Grant","year":"2004","journal-title":"Eur Urol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1207\/s15327914nc5301_8","article-title":"Milk consumption in relation to incidence of prostate, breast, colon, and rectal cancers: is there an independent effect?","volume":"53","author":"Zhang","year":"2005","journal-title":"Nutr Cancer"},{"key":"B20","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.urolonc.2005.05.023","article-title":"International comparisons of prostate cancer mortality rates with dietary practices and sunlight levels","volume":"24","author":"Colli","year":"2006","journal-title":"Urol Oncol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"163","DOI":"10.3390\/nu6010163","article-title":"A multicountry ecological study of cancer incidence rates in 2008 with respect to various risk-modifying factors","volume":"6","author":"Grant","year":"2013","journal-title":"Nutrients"},{"key":"B22","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.ehb.2014.07.002","article-title":"The role of nutrition and genetics as key determinants of the positive height trend","volume":"15","author":"Grasgruber","year":"2014","journal-title":"Econ Hum Biol"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1016\/j.ejca.2012.12.027","article-title":"Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012","volume":"49","author":"Ferlay","year":"2013","journal-title":"Eur J Cancer"},{"key":"B24","unstructured":""},{"key":"B25","volume-title":"European Cardiovascular Disease Statistics 2012","author":"Nichols","year":"2012"},{"key":"B26","unstructured":""},{"key":"B27","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/j.1467-9868.2005.00527.x","article-title":"Regularization and variable selection via the elastic net","volume":"67","author":"Zou","year":"2005","journal-title":"J R Stat Soc Series B Stat Methodol"},{"key":"B28","volume-title":"Statistical Methods in Medical Research","author":"Armitage","year":"1980"},{"key":"B29","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1093\/ajcn\/77.5.1146","article-title":"Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials","volume":"77","author":"Mensink","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"B30","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/S2213-8587(17)30283-8","article-title":"Association of dietary nutrients with blood lipids and blood pressure in 18 countries: a cross-sectional analysis from the PURE study","volume":"5","author":"Mente","year":"2017","journal-title":"Lancet Diabetes Endocrinol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1126\/science.1252787","article-title":"Cholesterol and cancer, in the balance","volume":"343","author":"Silvente-Poirot","year":"2014","journal-title":"Science"},{"key":"B32","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1111\/eci.12185","article-title":"The real role of prediagnostic high-density lipoprotein cholesterol and the cancer risk: a concise review","volume":"44","author":"V\u00edlchez","year":"2014","journal-title":"Eur J Clin Ivest"},{"key":"B33","unstructured":""},{"key":"B34","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1080\/01635580903407122","article-title":"Epidemiologic evidence on coffee and cancer","volume":"62","author":"Arab","year":"2010","journal-title":"Nutr Cancer"},{"key":"B35","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1097\/01.cej.0000236251.09232.7b","article-title":"Tomato lycopene extract supplementation decreases insulin-like growth factor-I levels in colon cancer patients","volume":"16","author":"Walfisch","year":"2007","journal-title":"Eur J Cancer Prev"},{"key":"B36","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1158\/1940-6207.CAPR-14-0172","article-title":"Garlic and onions: their cancer prevention properties","volume":"8","author":"Nicastro","year":"2015","journal-title":"Cancer Prev Res"},{"key":"B37","doi-asserted-by":"publisher","first-page":"693","DOI":"10.2105\/AJPH.2008.150508","article-title":"Smoking as a risk factor for prostate cancer: a meta-analysis of 24 prospective cohort studies","volume":"100","author":"Huncharek","year":"2010","journal-title":"Am J Public Health"},{"key":"B38","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1002\/ijc.23033","article-title":"Tobacco smoking and cancer: a meta-analysis","volume":"122","author":"Gandini","year":"2008","journal-title":"Int J Cancer"},{"key":"B39","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/S0091-7435(03)00110-5","article-title":"The effects of cessation from cigarette smoking on the lipid and lipoprotein profiles: a meta-analysis","volume":"37","author":"Maeda","year":"2003","journal-title":"Prev Med"},{"key":"B40","unstructured":""},{"key":"B41","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1080\/01635581.2011.596642","article-title":"Alcohol consumption and cancer risk","volume":"63","author":"Pelucchi","year":"2011","journal-title":"Nutr Cancer"},{"key":"B42","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.oraloncology.2016.10.001","article-title":"A local mechanism by which alcohol consumption causes cancer","volume":"62","author":"L\u00f3pez-L\u00e1zaro","year":"2016","journal-title":"Oral Oncol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"1630","DOI":"10.1038\/sj.bjc.6605337","article-title":"Alcoholic beverages intake and risk of thyroid cancer in the NIH-AARP Diet and Health Study","volume":"101","author":"Meinhold","year":"2009","journal-title":"Br J Cancer"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1038\/bjc.2012.136","article-title":"Alcohol intake and renal cell cancer risk: a meta-analysis","volume":"106","author":"Song","year":"2012","journal-title":"Br J Cancer"},{"key":"B45","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1016\/S1470-2045(15)00444-1","article-title":"Carcinogenicity of consumption of red and processed meat","volume":"16","author":"Bouvard","year":"2015","journal-title":"Lancet Oncol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.1038\/516S7a","article-title":"Perspective: time to face the fungal threat","volume":"516","author":"Wu","year":"2014","journal-title":"Nature"},{"key":"B47","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1016\/S1470-2045(16)30239-X","article-title":"Carcinogenicity of drinking coffee, mate, and very hot beverages","volume":"17","author":"Loomis","year":"2016","journal-title":"Lancet Oncol"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1476-511X-10-127","article-title":"Olive oil intake is inversely related to cancer prevalence: a systematic review and a meta-analysis of 13,800 patients and 23,340 controls in 19 observational studies","volume":"10","author":"Psaltopoulou","year":"2011","journal-title":"Lipids Health Dis"},{"key":"B49","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1021\/jf102319y","article-title":"Antioxidant, antiproliferative, and pro-apoptotic capacities of pentacyclic triterpenes found in the skin of olives on MCF-7 human breast cancer cells and their effects on DNA damage","volume":"59","author":"Allouche","year":"2010","journal-title":"J Agric Food Chem"},{"key":"B50","doi-asserted-by":"publisher","first-page":"464S","DOI":"10.1080\/07315724.2011.10719991","article-title":"Dairy products and cancer","volume":"30","author":"Lampe","year":"2011","journal-title":"J Am Coll Nutr"},{"key":"B51","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1093\/annonc\/mdr269","article-title":"Dairy products and colorectal cancer risk: a systematic review and meta-analysis of cohort studies","volume":"23","author":"Aune","year":"2012","journal-title":"Ann Oncol"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1080\/10408398.2011.629353","article-title":"Colorectal cancer and nonfermented milk, solid cheese, and fermented milk consumption: a systematic review and meta-analysis of prospective studies","volume":"54","author":"Ralston","year":"2014","journal-title":"Crit Rev Food Sci Nutr"},{"key":"B53","doi-asserted-by":"publisher","first-page":"87","DOI":"10.3945\/ajcn.113.067157","article-title":"Dairy products, calcium, and prostate cancer risk: a systematic review and meta-analysis of cohort studies","volume":"101","author":"Aune","year":"2015","journal-title":"Am J Clin Nutr"},{"key":"B54","first-page":"2643","article-title":"The use of a whey protein concentrate in the treatment of patients with metastatic carcinoma: a phase I-II clinical study","volume":"15","author":"Kennedy","year":"1995","journal-title":"Anticancer Res"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1016\/j.foodres.2007.07.005","article-title":"Bovine whey proteins \u2013 overview on their main biological properties","volume":"40","author":"Madureira","year":"2007","journal-title":"Food Res Int"},{"key":"B56","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s12937-016-0210-9","article-title":"Dairy products intake and cancer mortality risk: a meta-analysis of 11 population-based cohort studies","volume":"15","author":"Lu","year":"2016","journal-title":"Nutr J"},{"key":"B57","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1111\/j.1365-2621.2000.tb15977.x","article-title":"Thermal stability of bovine milk immunoglobulin G (IgG) and the effect of added thermal protectants on the stability","volume":"65","author":"Chen","year":"2000","journal-title":"J Food Sci"},{"key":"B58","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1203\/PDR.0b013e3181b4554a","article-title":"Retention of the immunological proteins of pasteurized human milk in relation to pasteurizer design and practice","volume":"66","author":"Czank","year":"2009","journal-title":"Pediatr Res"},{"key":"B59","doi-asserted-by":"publisher","first-page":"2884","DOI":"10.3168\/jds.2014-8920","article-title":"Effect of homogenization and pasteurization on the structure and stability of whey protein in milk","volume":"98","author":"Qi","year":"2015","journal-title":"J Dairy Sci"},{"key":"B60","first-page":"23","article-title":"Epidemiology of gastric cancer","volume-title":"Gastric Cancer","author":"Rugge","year":"2013"},{"key":"B61","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1007\/s00432-014-1637-z","article-title":"Red meat consumption and stomach cancer risk: a meta-analysis","volume":"140","author":"Song","year":"2014","journal-title":"J Cancer Res Clin Oncol"},{"key":"B62","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1093\/annonc\/mdt108","article-title":"Dietary patterns and gastric cancer risk: a systematic review and meta-analysis","volume":"24","author":"Bertuccio","year":"2013","journal-title":"Ann Oncol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1200\/JCO.2010.31.5200","article-title":"Total cholesterol and cancer risk in a large prospective study in Korea","volume":"29","author":"Kitahara","year":"2011","journal-title":"J Clin Oncol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1016\/S0140-6736(07)61416-0","article-title":"Human papillomavirus and cervical cancer","volume":"370","author":"Schiffman","year":"2007","journal-title":"Lancet"},{"key":"B65","doi-asserted-by":"publisher","first-page":"9","DOI":"10.20892\/j.issn.2095-3941.2016.0084","article-title":"Epidemiology of ovarian cancer: a review","volume":"14","author":"Reid","year":"2017","journal-title":"Cancer Biol Med"},{"key":"B66","doi-asserted-by":"publisher","first-page":"1827","DOI":"10.1093\/jnci\/djr483","article-title":"Preventable exposures associated with human cancers","volume":"103","author":"Cogliano","year":"2011","journal-title":"J Natl Cancer Inst"},{"key":"B67","doi-asserted-by":"publisher","first-page":"a439","DOI":"10.1136\/bmj.a439","article-title":"Association between muscular strength and mortality in men: prospective cohort study","volume":"337","author":"Ruiz","year":"2008","journal-title":"BMJ"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwx345","article-title":"Does strength promoting exercise confer unique health benefits? A pooled analysis of eleven population cohorts with all-cause, cancer, and cardiovascular mortality endpoints","author":"Stamatakis","year":"2017","journal-title":"Am J Epidemiol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1038\/ijo.2014.199","article-title":"Energy balance measurement: when something is not better than nothing","volume":"39","author":"Dhurandhar","year":"2015","journal-title":"Int J Obes (Lond)"},{"key":"B70","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1080\/13625180802511541","article-title":"Women\u2019s contraceptive practices and sexual behaviour in Europe","volume":"13","author":"Cibula","year":"2008","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"B71","unstructured":""}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fonc.2018.00151\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T04:21:23Z","timestamp":1528863683000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fonc.2018.00151\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,13]]},"references-count":71,"alternative-id":["10.3389\/fonc.2018.00151"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2018.00151","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,13]]},"article-number":"151"}}