{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:07:28Z","timestamp":1785150448047,"version":"3.55.0"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T00:00:00Z","timestamp":1628467200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Primary bone lymphoma (PBL) is a less frequent type of extranodal lymphoma, which is defined as a single skeletal tumor or multiple bone lesions without visceral or lymph node involvement. Most published cases have reported diffused large B cell lymphoma (DLBCL) of PBL, and the prognosis is good after conventional treatment. Primary T-cell lymphoma is extremely rare in the literature. The clinical symptoms, imaging findings, diagnosis, treatment and prognosis of primary T-cell lymphoma of bone are still unclear. The case details a young male patient who was treated for bone tuberculosis and was diagnosed with T-cell lymphoma during an open surgical biopsy. Further imaging evidence showed the lymphoma was localized within the femur. The patient responded poorly to combined chemo- and radiotherapy. He was confirmed with local lung metastases 11 months later and died at the 17th month of onset. I would like to provide PBL entities with some rare information about primary bone peripheral T-cell lymphoma and discuss the best strategy for the treatment of rare PBL subtypes.<\/jats:p>","DOI":"10.3389\/fonc.2021.690819","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T04:51:17Z","timestamp":1628484677000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Imaging Features of Primary T Cell Lymphoma in Bone: A Case Report and Review of Literature"],"prefix":"10.3389","volume":"11","author":[{"given":"Suli","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianqiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,8,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s004020100316","article-title":"Malignant Lymphoma of Bone","volume":"122","author":"D\u00fcrr","year":"2002","journal-title":"Arch Prthopaedic Trauma Surg"},{"key":"B2","article-title":"Nouvelles Recherches sur les R\u00e9ticulosarcomes de la Moelle Osseuse (Sarcoma D\u2019ewing)","volume":"17","author":"Oberling","year":"1928","journal-title":"Bull Ass Franc Cancer"},{"key":"B3","article-title":"Primary Reticulum Cell Sarcoma of Bone","volume":"1939","author":"Parker","year":"1939","journal-title":"Surgery Gynecol Obstet"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199007000-00006","article-title":"Malignant Lymphoma Involving the Mandible. 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