{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:06:33Z","timestamp":1783483593168,"version":"3.55.0"},"reference-count":39,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T00:00:00Z","timestamp":1637798400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Cerebellar liponeurocytoma is a rare benign neoplasm of the central nervous system, which arises mainly in adult patients with only 3 cases reported in children. Due to its rarity, the diagnosis and treatment strategies for cerebellar liponeurocytoma remain unclear. The purpose of this study was to explore the epidemiology, clinical features, imaging findings, pathological characteristics, different diagnoses, treatment, and prognosis of cerebellar liponeurocytoma in juveniles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Description<\/jats:title><jats:p>A 5-year-old boy was admitted to the department of neurosurgery due to a 5-month history of headaches, nausea, vomiting, dizziness, dysphoria, as well as visual blurring associated with the peak of the headache. Magnetic resonance imaging showed a 4.9\u00d75.4\u00d76.2 cm mass located in the fourth ventricle and cerebellar vermis combined with hydrocephalus and periventricular edema. The mass was completely removed, and pathological examination indicated a cerebellar liponeurocytoma of the World Health Organization Grade II classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study was the first to report a cerebellar liponeurocytoma with total tumor resection and adjuvant radiotherapy in a pediatric patient. Total tumor resection and postoperative radiotherapy together with close and long-term follow-up seem to be the optimal treatment strategy for juvenile patients. However, the side-effect of radiation needs to be considered.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fonc.2021.759581","type":"journal-article","created":{"date-parts":[[2021,11,30]],"date-time":"2021-11-30T23:46:55Z","timestamp":1638316015000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Cerebellar Liponeurocytoma Mimicking Medulloblastoma: Case Report of a Childhood and Literature Review"],"prefix":"10.3389","volume":"11","author":[{"given":"Changhui","family":"Dong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yining","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunqian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-016-1545-1","article-title":"The 2016 World Health Organization Classification of Tumors of the Central Nervous System: A Summary","volume":"131","author":"Louis","year":"2016","journal-title":"Acta Neuropathol"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.08.156","article-title":"Cerebellar Liponeurocytoma: The Dilemma of Multifocality","volume":"120","author":"Khatri","year":"2018","journal-title":"World Neurosurg"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.09.001","article-title":"Liponeurocytoma: Systematic Review of a Rare Entity","volume":"120","author":"Gembruch","year":"2018","journal-title":"World Neurosurg"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1007\/bf00690447","article-title":"Mixed Mesenchymal and Neuroectodermal Tumor of the Cerebellum","volume":"41","author":"Bechtel","year":"1978","journal-title":"Acta Neuropathol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1993.tb00410.x","article-title":"Neurocytoma\/Lipoma (Neurolipocytoma) of the Cerebellum","volume":"19","author":"Ellison","year":"1993","journal-title":"Neuropathol Appl Neurobiol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(93)90113-u","article-title":"Lipidized Medulloblastoma in Adults","volume":"24","author":"Davis","year":"1993","journal-title":"Hum Pathol"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s10014-014-0210-4","article-title":"Findings From Positron Emission Tomography and Genetic Analyses for Cerebellar Liponeurocytoma","volume":"32","author":"Takami","year":"2015","journal-title":"Brain Tumor Pathol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1007\/s00292-002-0530-8","article-title":"The New WHO Classification of Tumors of the Nervous System 2000. 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