{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:12:58Z","timestamp":1753891978074,"version":"3.41.2"},"reference-count":119,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T00:00:00Z","timestamp":1664841600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010477","name":"Intuitive Surgical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010477","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>There are standard treatment guidelines for the surgical management of rectal cancer, that are advocated by recognized physician societies. But, owing to disparities in access and affordability of various treatment options, there remains an unmet need for personalizing these international guidelines to Indian settings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical Robotic Surgery Association (CRSA) set up the Indian rectal cancer expert group, with a pre-defined selection criterion and comprised of the leading surgical oncologists and gastrointestinal surgeons managing rectal cancer in India. Following the constitution of the expert Group, members identified three areas of focus and 12 clinical questions. A thorough review of the literature was performed, and the evidence was graded as per the levels of evidence by Oxford Centre for Evidence-Based Medicine. The consensus was built using the modified Delphi methodology of consensus development. A consensus statement was accepted only if \u226575% of the experts were in agreement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Using the results of the review of the literature and experts\u2019 opinions; the expert group members drafted and agreed on the final consensus statements, and these were classified as \u201cstrong or weak\u201d, based on the GRADE framework.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The expert group adapted international guidelines for the surgical management of localized and locally advanced rectal cancer to Indian settings. It will be vital to disseminate these to the wider surgical oncologists and gastrointestinal surgeons\u2019 community in India.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fonc.2022.1002530","type":"journal-article","created":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T08:20:36Z","timestamp":1664871636000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Robotic Surgery Association (India Chapter) and Indian rectal cancer expert group\u2019s practical consensus statements for surgical management of localized and locally advanced rectal cancer"],"prefix":"10.3389","volume":"12","author":[{"given":"S. P.","family":"Somashekhar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avanish","family":"Saklani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagannath","family":"Dixit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagdish","family":"Kothari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Nayak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O. V.","family":"Sudheer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surender","family":"Dabas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jagadishwar","family":"Goud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkatesh","family":"Munikrishnan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavan","family":"Sugoor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasanth","family":"Penumadu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ramachandra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpa","family":"Mehendale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akhil","family":"Dahiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,10,4]]},"reference":[{"key":"B1","unstructured":"Globocan 2020 report"},{"key":"B2","unstructured":"Report of national cancer registry programme 2020- national cancer research programme"},{"key":"B3","unstructured":"National comprehensive cancer network (NCCN) guidelines- rectal cancer version 1.02022"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001762","article-title":"The American society of colon and rectal surgeons clinical practice guidelines for the management of rectal cancer","volume":"63","author":"You","year":"2020","journal-title":"Dis Colon Rectum"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-6462-1","article-title":"AJCC 8th edition: Colorectal cancer","volume":"25","author":"Weiser","year":"2018","journal-title":"Ann Surg Oncol"},{"key":"B6","unstructured":"PhillipsB\n          Oxford Centre for evidence-based medicine levels of evidence2009"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.00457","article-title":"Delphi Technique in health sciences: A map","volume":"8","author":"Niederberger","year":"2020","journal-title":"Front Public Health"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"key":"B9","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1200\/JCO.2012.45.3258","article-title":"Preoperative magnetic resonance imaging assessment of circumferential resection margin predicts disease-free survival and local recurrence: 5-year follow-up results of the MERCURY study","volume":"32","author":"Taylor","year":"2014","journal-title":"J Clin Oncol"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001193","article-title":"Prospective validation of a low rectal cancer magnetic resonance imaging staging system and development of a local recurrence risk stratification model: The MERCURY II study","volume":"263","author":"Battersby","year":"2016","journal-title":"Ann Surg"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000611","article-title":"Diagnostic accuracy of MRI for assessment of T category and circumferential resection margin involvement in patients with rectal cancer: A meta-analysis","volume":"59","author":"Zhang","year":"2016","journal-title":"Dis Colon Rectum"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.23736\/S0026-4733.17.07392-8","article-title":"Preoperative staging of rectal cancer using magnetic resonance imaging: Comparison with pathological staging","volume":"73","author":"Faletti","year":"2018","journal-title":"Minerva Chir."},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1159\/000099174","article-title":"Conventional CT for the prediction of an involved circumferential resection margin in primary rectal cancer","volume":"25","author":"Wolberink","year":"2007","journal-title":"Dig Dis"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2011.02830.x","article-title":"A critical appraisal of endorectal ultrasound and transanal endoscopic microsurgery and decision-making in early rectal cancer","volume":"14","author":"Ashraf","year":"2012","journal-title":"Colorect Dis"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-25292","article-title":"Routine use of transrectal ultrasound in rectal carcinoma: Results of a prospective multicenter study","volume":"34","author":"Marusch","year":"2002","journal-title":"Endoscopy"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2323031368","article-title":"Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging\u2013a meta-analysis","volume":"232","author":"Bipat","year":"2004","journal-title":"Radiology"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21651","article-title":"Preoperative chest computerized tomography in patients with locally advanced mid or lower rectal cancer: its role in staging and impact on treatment strategy","volume":"102","author":"Choi","year":"2010","journal-title":"J Surg Oncol"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1670-y","article-title":"Preoperative staging of patients with liver metastases of colorectal carcinoma. does PET\/CT really add something to multidetector CT","volume":"18","author":"Ramos","year":"2011","journal-title":"Ann Surg Oncol"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2021.12.019","article-title":"Prospective study to assess the role of FDG PET\/CT in detecting systemic metastatic spread in rectal cancers with lateral pelvic lymph nodes","volume":"48","author":"Agrawal","year":"2022","journal-title":"Eur J Surg Oncol"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13707","article-title":"College of American pathologists tumor regression grading system for long-term outcome in patients with locally advanced rectal cancer","volume":"26","author":"Chen","year":"2021","journal-title":"Oncologist"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/s1072-7515(01)01159-0","article-title":"Assessing the predictive value of clinical complete response to neoadjuvant therapy for rectal cancer: An analysis of 488 patients","volume":"194","author":"Hiotis","year":"2002","journal-title":"J Am Coll Surg"},{"key":"B22","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1002\/bjs.8700","article-title":"The surgical significance of residual mucosal abnormalities in rectal cancer following neoadjuvant chemoradiotherapy","volume":"99","author":"Smith","year":"2012","journal-title":"Br J Surg"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1007\/s13193-020-01218-z","article-title":"Can post-treatment MRI features predict pathological circumferential resection margin (pCRM) involvement in low rectal tumors","volume":"11","author":"Patra","year":"2020","journal-title":"Indian J Surg Oncol"},{"key":"B24","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1007\/s00261-020-02708-y","article-title":"Accuracy of MRI for nodal restaging in rectal cancer: A retrospective study of 166 cases","volume":"46","author":"Pangarkar","year":"2021","journal-title":"Abdom Radiol (NY)"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31828f6c91","article-title":"Multicenter evaluation of rectal cancer ReImaging pOst neoadjuvant (MERRION) therapy","volume":"259","author":"Hanly","year":"2014","journal-title":"Ann Surg"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12372","article-title":"Is follow-up CT imaging of the chest and abdomen necessary after preoperative neoadjuvant therapy in rectal cancer patients without evidence of metastatic disease at diagnosis","volume":"15","author":"Jaffe","year":"2013","journal-title":"Colorect Dis"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.21037\/jgo.2016.01.08","article-title":"Restaging after neoadjuvant chemoradiation in rectal cancers: Is histology the key in patient selection","volume":"7","author":"Singhal","year":"2016","journal-title":"J Gastrointest Oncol"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181a3e54b","article-title":"Transanal endoscopic microsurgery versus conventional transanal excision for patients with early rectal cancer","volume":"249","author":"Christoforidis","year":"2009","journal-title":"Ann Surg"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000309","article-title":"Transanal endoscopic microsurgery versus standard transanal excision for the removal of rectal neoplasms: A systematic review and meta-analysis","volume":"58","author":"Clancy","year":"2015","journal-title":"Dis Colon Rectum"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2009.05.001","article-title":"Transanal endoscopic microsurgery versus total mesorectal excision of T1 rectal adenocarcinomas with curative intention","volume":"35","author":"De Graaf","year":"2009","journal-title":"Eur J Surg Oncol"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2006.04.010","article-title":"Local recurrence after transanal endoscopic microsurgery for rectal polyps and early cancers","volume":"13","author":"Ganai","year":"2006","journal-title":"Ann Surg Oncol"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181e73f33","article-title":"Treatment of recurrence after transanal endoscopic microsurgery (TEM) for T1 rectal cancer","volume":"53","author":"Doornebosch","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"B33","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1007\/s10151-012-0950-2","article-title":"The outcome of rectal cancer after early salvage TME following TEM compared with primary TME: Acase-matched study","volume":"17","author":"Levic","year":"2013","journal-title":"Tech Coloproctol"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-004-8930-x","article-title":"Transanal endoscopic versus total mesorectal laparoscopic resections of T2-N0 low rectal cancers after neoadjuvant treatment: A prospective randomized trial with a 3-years minimum follow-up period","volume":"19","author":"Lezoche","year":"2005","journal-title":"Surg Endosc"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-007-9596-y","article-title":"A prospective randomized study with a 5-year minimum follow-up evaluation of transanal endoscopic microsurgery versus laparoscopic total mesorectal excision after neoadjuvant therapy","volume":"22","author":"Lezoche","year":"2008","journal-title":"Surg Endosc"},{"key":"B36","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1001\/jamasurg.2018.3752","article-title":"Long-term oncological and functional outcomes of chemoradiotherapy followed by organ-sparing transanal endoscopic microsurgery for distal rectal cancer: The CARTS study","volume":"154","author":"Stijns","year":"2019","journal-title":"JAMA Surg"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1735587","article-title":"A meta-analysis of transanal endoscopic microsurgery versus total mesorectal excision in the treatment of rectal cancer","volume":"7","author":"Ahmad","year":"2021","journal-title":"Surg J (N Y)"},{"key":"B38","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/S2468-1253(20)30333-2","article-title":"Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): A randomised, open-label feasibility study","volume":"6","author":"Bach","year":"2021","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"B39","doi-asserted-by":"publisher","first-page":"6","DOI":"10.47717\/turkjsurg.2021.5057","article-title":"Transanal minimal invasive surgery (TAMIS): Safety and feasibility for the resection of benign and malignant lesions of the rectum","volume":"37","author":"Mehraj","year":"2021","journal-title":"Turk J Surg"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60485-2","article-title":"Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial","volume":"373","author":"Quirke","year":"2009","journal-title":"Lancet"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2018.1607","article-title":"Association of plane of total mesorectal excision with prognosis of rectal cancer: Secondary analysis of the CAO\/ARO\/AIO-04 phase 3 randomized clinical trial","volume":"153","author":"Kitz","year":"2018","journal-title":"JAMA Surg"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1007\/BF02048158","article-title":"Distribution of metastatic lymph nodes in colorectal cancer by the modified clearing method","volume":"37","author":"Morikawa","year":"1994","journal-title":"Dis Colon Rectum"},{"key":"B43","article-title":"Lymph node metastases detected in the mesorectum distal to carcinoma of the rectum by the clearing method: Justification of total mesorectal excision","volume":"184","author":"Hida","year":"1997","journal-title":"J Am Coll Surg"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1067\/msy.1998.91361","article-title":"Total mesorectal excision is not necessary for cancers of the upper rectum","volume":"124","author":"Lopez-Kostner","year":"1998","journal-title":"Surgery"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1007\/s13193-019-00888-8","article-title":"Impact of length of distal margin on outcomes following sphincter preserving surgery for middle and lower third rectal cancers","volume":"10","author":"Bhamre","year":"2019","journal-title":"Indian J Surg Oncol"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199910000-00010","article-title":"Safety and efficacy of low anterior resection for rectal cancer: 681 consecutive cases from a specialty service","volume":"230","author":"Enker","year":"1999","journal-title":"Ann Surg"},{"key":"B47","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1007\/s00384-012-1590-8","article-title":"Abdominoperineal resection and low anterior resection: Comparison of long-term oncologic outcome in matched patients with lower rectal cancer","volume":"28","author":"Kim","year":"2013","journal-title":"Int J Colorect Dis"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5679","article-title":"The Swedish rectal cancer registry","volume":"94","author":"P\u00e5hlman","year":"2007","journal-title":"Br J Surg"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.11.039","article-title":"The abdominoperineal resection itself is associated with an adverse outcome: The European experience based on a pooled analysis of five European randomised clinical trials on rectal cancer","volume":"45","author":"den Dulk","year":"2009","journal-title":"Eur J Cancer"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2011.05.001","article-title":"A systematic review of cancer related patient outcomes after anterior resection and abdominoperineal excision for rectal cancer in the total mesorectal excision era","volume":"20","author":"How","year":"2011","journal-title":"Surg Oncol"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-021-00400-1","article-title":"Sphincter preservation in patients with low rectal cancer: Striking the right oncological balance","volume":"12","author":"Luvisetto","year":"2021","journal-title":"Discovery Oncol"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000594","article-title":"Comparative effectiveness of sphincter-sparing surgery versus abdominoperineal resection in rectal cancer: Patient-reported outcomes in national surgical adjuvant breast and bowel project randomized trial r-04","volume":"261","author":"Russell","year":"2015","journal-title":"Ann Surg"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-002-0474-8","article-title":"Sphincter saving rectum resection is the standard procedure for low rectal cancer","volume":"18","author":"Di Betta","year":"2003","journal-title":"Int J Colorect Dis"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900297","article-title":"Ultra-low anterior resection and coloanal pouch reconstruction for carcinoma of the distal rectum","volume":"21","author":"Guillem","year":"1997","journal-title":"World J Surg"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000080823.38569.b0","article-title":"Quality of life in rectal cancer patients: A four-year prospective study","volume":"238","author":"Engel","year":"2003","journal-title":"Ann Surg"},{"key":"B56","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10147-019-01485-z","article-title":"Japanese Society for cancer of the colon and rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer","volume":"25","author":"Hashiguchi","year":"2020","journal-title":"Int J Clin Oncol"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-003-0088-4","article-title":"Early results of intersphincteric resection for patients with very low rectal cancer: An active approach to avoid a permanent colostomy","volume":"47","author":"Saito","year":"2004","journal-title":"Dis Colon Rectum"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000154551.06768.e1","article-title":"Sphincter-saving resection for all rectal carcinomas: The end of the 2-cm distal rule","volume":"241","author":"Rullier","year":"2005","journal-title":"Ann Surg"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25791","article-title":"Oncologic safety and bowel function after ultralow anterior resection with or without intersphincteric resection for low lying rectal cancer: Comparative cross sectional study","volume":"3","author":"Sakr","year":"2019","journal-title":"J Surg Oncol"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1111\/ans.17405","article-title":"Comparative study of functional outcomes between ultra-low anterior resection and inter-sphincteric resection: A propensity matched analysis","volume":"92","author":"Gori","year":"2022","journal-title":"ANZ J Surg"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6916","article-title":"European Extralevator abdominoperineal excision study group. multicentre experience with extralevator abdominoperineal excision for low rectal cancer","volume":"97","author":"West","year":"2010","journal-title":"Br J Surg"},{"key":"B62","article-title":"Meta-analysis of extralevator abdominoperineal excision for rectal cancer","volume":"20","author":"Chen","year":"2017","journal-title":"Zhonghua Wei Chang Wai Ke Za Zhi"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2016.02.022","article-title":"Extralevator vs conventional abdominoperineal resection for rectal cancer-a systematic review and meta-analysis","volume":"212","author":"Negoi","year":"2016","journal-title":"Am J Surg"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9522","article-title":"Multicentre propensity score-matched analysis of conventional versus extended abdominoperineal excision for low rectal cancer","volume":"101","author":"Ortiz","year":"2014","journal-title":"Br J Surg"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12921","article-title":"Extralevator abdominoperineal excision for low rectal cancer: A systematic review and meta-analysis of the short-term outcome","volume":"17","author":"Zhou","year":"2015","journal-title":"Colorect Dis"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2015.01.017","article-title":"Prospective controlled study of the safety and oncological outcomes of ELAPE procure with definitive anatomic landmarks versus conventional APE for lower rectal cancer","volume":"41","author":"Shen","year":"2015","journal-title":"Eur J Surg Oncol"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2012.05.001","article-title":"Randomized clinical trial of conventional versus cylindrical abdominoperineal resection for locally advanced lower rectal cancer","volume":"204","author":"Han","year":"2012","journal-title":"Am J Surg"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.232810","article-title":"Preliminary outcome of individualized abdominoperineal excision for locally advanced low rectal cancer","volume":"131","author":"Zheng","year":"2018","journal-title":"Chin Med J (Engl)"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2016.03.002","article-title":"The circumferential resection margins status: A comparison of robotic, laparoscopic and open total mesorectal excision for mid and low rectal cancer","volume":"42","author":"de Jesus","year":"2016","journal-title":"Eur J Surg Oncol"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1007\/s13193-020-01137-z","article-title":"Comparative evaluation of the short-term treatment outcomes between open, laparoscopic- and robotic-assisted surgical approaches for rectal cancer treatment","volume":"11","author":"Somashekhar","year":"2020","journal-title":"Indian J Surg Oncol"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414882","article-title":"A randomized trial of laparoscopic versus open surgery for rectal cancer","volume":"372","author":"Bonjer","year":"2015","journal-title":"N Engl J Med"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)70205-0","article-title":"Open versus laparoscopic surgery for mid-rectal or low-rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): Survival outcomes of an open-label, non-inferiority, randomised controlled trial","volume":"15","author":"Jeong","year":"2014","journal-title":"Lancet Oncol"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.10529","article-title":"Effect of laparoscopic-assisted resection vs open resection of stage II or III rectal cancer on pathologic outcomes: The ACOSOG Z6051 randomized clinical trial","volume":"314","author":"Fleshman","year":"2015","journal-title":"JAMA"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.12009","article-title":"Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in rectal cancer: The ALaCaRT randomized clinical trial","volume":"314","author":"Stevenson","year":"2015","journal-title":"JAMA"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1007\/s12262-013-1003-4","article-title":"Prospective randomized study comparing robotic-assisted surgery with traditional laparotomy for rectal cancer-Indian study","volume":"77","author":"Somashekhar","year":"2015","journal-title":"Indian J Surg"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1038\/srep26981","article-title":"Robotic-assisted surgery versus open surgery in the treatment of rectal cancer: The current evidence","volume":"6","author":"Liao","year":"2016","journal-title":"Sci Rep"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2015.02.020","article-title":"The effect of surgical approach on short-term oncologic outcomes in rectal cancer surgery","volume":"158","author":"Midura","year":"2015","journal-title":"Surgery"},{"key":"B78","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1097\/SLA.0000000000003227","article-title":"Open versus laparoscopic versus robotic versus transanal mesorectal excision for rectal cancer: A systematic review and network meta-analysis","volume":"270","author":"Simillis","year":"2019","journal-title":"Ann Surg"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.7219","article-title":"Effect of robotic-assisted vs conventional laparoscopic surgery on risk of conversion to open laparotomy among patients undergoing resection for rectal cancer: The ROLARR randomized clinical trial","volume":"318","author":"Jayne","year":"2017","journal-title":"JAMA"},{"key":"B80","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1186\/s13063-018-2726-0","article-title":"Exploring and adjusting for potential learning effects in ROLARR: a randomised controlled trial comparing robotic-assisted vs","volume":"19","author":"Corrigan","year":"2018","journal-title":"stand laparosc Surg rectal Cancer resect Trials"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrab083","article-title":"Outcomes of robot-assisted versus conventional laparoscopic low anterior resection in patients with rectal cancer: Propensity-matched analysis of the national clinical database in Japan","volume":"5","author":"Matsuyama","year":"2021","journal-title":"BJS Open"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14010180","article-title":"Robotic-assisted vs. standard laparoscopic surgery for rectal cancer resection: A systematic review and meta-analysis of 19,731 patients","volume":"14","author":"Safiejko","year":"2021","journal-title":"Cancers (Basel)"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1002\/rcs.1965","article-title":"Robotic versus laparoscopic sphincter-preserving total mesorectal excision: A propensity case-matched analysis","volume":"15","author":"Sugoor","year":"2019","journal-title":"Int J Med Robot"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12020307","article-title":"The role of robotic visceral surgery in patients with adhesions: A systematic review and meta-analysis","volume":"12","author":"Milone","year":"2022","journal-title":"J Pers Med"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6363-1","article-title":"Short-term and long-term results of a randomized study comparing high tie and low tie inferior mesenteric artery ligation in laparoscopic rectal anterior resection: Subanalysis of the HTLT (High tie vs. low tie) study","volume":"33","author":"Fujii","year":"2019","journal-title":"Surg Endosc"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001693","article-title":"Meta-analysis and trial sequential analysis of randomized controlled trials comparing high and low ligation of the inferior mesenteric artery in rectal cancer surgery","volume":"63","author":"Hajibandeh","year":"2020","journal-title":"Dis Colon Rectum"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v13.i8.871","article-title":"Genitourinary function and defecation after colorectal cancer surgery with low- and high-ligation of the inferior mesenteric artery: A meta-analysis","volume":"13","author":"Bai","year":"2021","journal-title":"World J Gastrointest Surg"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1007\/s11701-020-01095-2","article-title":"A prospective study of real-time identification of line of transection in robotic colorectal cancer surgery by ICG","volume":"15","author":"Somashekhar","year":"2021","journal-title":"J Robot Surg"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-010-0965-6","article-title":"And laparoscopic assistance","volume":"24","author":"Sylla","year":"2010","journal-title":"Surg Endosc"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-015-1342-1","article-title":"Transanal total mesorectal excision assisted by single-port laparoscopic surgery for low rectal cancer","volume":"19","author":"Chen","year":"2015","journal-title":"Tech Coloproctol"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.5114\/wiitm.2015.54060","article-title":"Transanal total mesorectal excision (TATME) - preliminary findings","volume":"10","author":"Pi\u0105tkowski","year":"2015","journal-title":"Wideochir Inne Tech Maloinwazyjne"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S181214","article-title":"Transanal total mesorectal excision for low rectal cancer: A case-matched study comparing TaTME versus standard laparoscopic TME","volume":"10","author":"Rubinkiewicz","year":"2018","journal-title":"Cancer Manag Res"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-017-5836-y","article-title":"Transanal versus abdominal low rectal dissection for rectal cancer: Long-term results of the bordeaux' randomized trial","volume":"32","author":"Denost","year":"2018","journal-title":"Surg Endosc"},{"key":"B94","doi-asserted-by":"publisher","first-page":"36","DOI":"10.5114\/wiitm.2019.82733","article-title":"Evaluation of the learning curve of transanal total mesorectal excision: single-centre experience","volume":"15","author":"Rubinkiewicz","year":"2020","journal-title":"Wideochir Inne Tech Maloinwazyjne"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-018-1771-8","article-title":"Transanal total mesorectal excision for rectal cancer: Evaluation of the learning curve","volume":"22","author":"Koedam","year":"2018","journal-title":"Tech Coloproctol"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6360-4","article-title":"Defining the learning curve for transanal total mesorectal excision for rectal adenocarcinoma","volume":"34","author":"Lee","year":"2020","journal-title":"Surg Endosc"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-015-4615-x","article-title":"COLOR III: a multicentre randomised clinical trial comparing transanal TME versus laparoscopic TME for mid and low rectal cancer","volume":"30","author":"Deijen","year":"2016","journal-title":"Surg Endosc"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000011410","article-title":"The application of transanal total mesorectal excision for patients with middle and low rectal cancer: A systematic review and meta-analysis","volume":"97","author":"Hu","year":"2018","journal-title":"Med (Baltimore)."},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-019-07167-1","article-title":"Comparison of pathological outcomes after transanal versus laparoscopic total mesorectal excision: a prospective study using data from randomized control trial","volume":"34","author":"Zeng","year":"2020","journal-title":"Surg Endosc"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2019.0828","article-title":"Transanal versus laparoscopic total mesorectal excision: A comparative prospective clinical trial from two centers","volume":"30","author":"Zuhdy","year":"2020","journal-title":"J Laparoendosc Adv Surg Tech A."},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001948","article-title":"TaTME registry collaborative. transanal total mesorectal excision: International registry results of the first 720 cases","volume":"266","author":"Penna","year":"2017","journal-title":"Ann Surg"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002862","article-title":"A multicenter matched comparison of transanal and robotic total mesorectal excision for mid and low-rectal adenocarcinoma","volume":"270","author":"Lee","year":"2019","journal-title":"Ann Surg"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6340-8","article-title":"Comparison of early experience of robotic and transanal total mesorectal excision using propensity score matching","volume":"33","author":"Law","year":"2019","journal-title":"Surg Endosc"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-018-2962-5","article-title":"Transanal total mesorectal excision: is it necessary in the era of robots","volume":"33","author":"Kuo","year":"2018","journal-title":"Int J Colorect Dis"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1111\/codi.14378","article-title":"Medrobotics flex transanal excision of a rectal gastrointestinal stromal tumour: First video of the transanal flex robot used in a human - a video vignette","volume":"20","author":"Paull","year":"2018","journal-title":"Colorect Dis"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-018-1788-z","article-title":"Direct target NOTES: Prospective applications for next generation robotic platforms","volume":"22","author":"Atallah","year":"2018","journal-title":"Tech Coloproctol"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6329-3","article-title":"Robotic transanal minimally invasive surgery (TAMIS) with the newest robotic surgical platform: A multi-institutional north American experience","volume":"33","author":"Liu","year":"2019","journal-title":"Surg Endosc"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-017-1697-6","article-title":"Assessment of a flexible robotic system for endoluminal applications and transanal total mesorectal excision (taTME): Could this be the solution we have been searching for","volume":"21","author":"Atallah","year":"2017","journal-title":"Tech Coloproctol"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31078-X","article-title":"Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the international watch & wait database (IWWD): An international multicentre registry study","volume":"391","author":"van der Valk","year":"2018","journal-title":"Lancet"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-019474","article-title":"Can we save the rectum by watchful waiting or TransAnal microsurgery following (chemo) radiotherapy versus total mesorectal excision for early REctal cancer (STAR-TREC study)?: Protocol for a multicentre, randomised feasibility study","volume":"7","author":"Rombouts","year":"2017","journal-title":"BMJ Open"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-017-5990-2","article-title":"St.Gallen consensus on safe implementation of transanal total mesorectal excision","volume":"32","author":"Adamina","year":"2018","journal-title":"Surg Endosc"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.11459","article-title":"Transanal total mesorectal excision for rectal cancer has been suspended in Norway","volume":"107","author":"Wasmuth","year":"2020","journal-title":"Br J Surg"},{"key":"B113","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15143","article-title":"The ACPGBI recommends pause for reflection on transanal total mesorectal excision","volume":"22","author":"Fearnhead","year":"2020","journal-title":"Colorect Dis"},{"key":"B114","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09090-4","article-title":"UEG and EAES rapid guideline: Systematic review, meta-analysis, GRADE assessment and evidence-informed European recommendations on TaTME for rectal cancer","volume":"36","author":"Milone","year":"2022","journal-title":"Surg Endosc"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(17)30074-2","article-title":"A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: A systematic review and meta-analysis","volume":"2","author":"Dossa","year":"2017","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00120-5","article-title":"High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study","volume":"16","author":"Appelt","year":"2015","journal-title":"Lancet Oncol"},{"key":"B117","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00467-2","article-title":"Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): A propensity-score matched cohort analysis","volume":"17","author":"Renehan","year":"2016","journal-title":"Lancet Oncol"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.1007\/s13193-021-01421-6","article-title":"Watch and wait approach after neoadjuvant chemoradiotherapy in rectal cancer: Initial experience in the Indian subcontinent","volume":"12","author":"Engineer","year":"2021","journal-title":"Indian J Surg Oncol"},{"key":"B119","doi-asserted-by":"publisher","first-page":"13","DOI":"10.21037\/jgo.2019.12.04","article-title":"Impact of delaying surgery after chemoradiation in rectal cancer: Outcomes from a tertiary cancer centre in India","volume":"11","author":"Kammar","year":"2020","journal-title":"J Gastrointest Oncol"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.1002530\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T08:20:43Z","timestamp":1664871643000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.1002530\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,4]]},"references-count":119,"alternative-id":["10.3389\/fonc.2022.1002530"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2022.1002530","relation":{},"ISSN":["2234-943X"],"issn-type":[{"type":"electronic","value":"2234-943X"}],"subject":[],"published":{"date-parts":[[2022,10,4]]},"article-number":"1002530"}}