{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:10:17Z","timestamp":1753891817883,"version":"3.41.2"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T00:00:00Z","timestamp":1643846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017957","name":"Health Commission of Guizhou Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017957","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to determine the optimal dividing order of anatomic pulmonary resection under uniportal video-assisted thoracoscopic surgery (uni-VATS) for patients with right upper peripheral lung cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who met the eligibility criteria were randomly allocated into the aBVA and VAB groups. In the aBVA group, the surgical procedure proceeded from the posterior to the anterior region (from the deeper to the superficial site). In the VAB group, the dissection orders were vein first followed by arterial branches, followed by the bronchus. Clinical data were collected and analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty patients were randomly allocated to the aBVA group (<jats:italic>n<\/jats:italic> = 30) and the VAB group (<jats:italic>n<\/jats:italic> = 30). The operation time in the aBVA group (230.500 \u00b1 68.360 min) was significantly shorter than that in the VAB group (305.600 \u00b1 107.821 min) (<jats:italic>p<\/jats:italic> = 0.01). The blood loss in the aBVA group (104.000 \u00b1 70.935 ml) was significantly lower than that in the VAB group (391.000 \u00b1 625.175 ml) (<jats:italic>p<\/jats:italic> = 0.01). Two patients in the VAB group underwent conversion to 2-portal VATS. The number of lymph nodes (13.367 \u00b1 5.436 vs. 10.333 \u00b1 7.279, <jats:italic>p<\/jats:italic> = 0.072) and lymph node stations (5.067 \u00b1 1.574 vs. 4.467 \u00b1 2.345, <jats:italic>p<\/jats:italic> = 0.567) were comparable between the two groups. The differences in the postoperative drainage tube time (5.033 \u00b1 3.113 vs. 6.467 \u00b1 4.447 days, <jats:italic>p<\/jats:italic> = 0.278) and hospital stay (8.233 \u00b1 3.390 vs. 9.433 \u00b1 4.523 days, <jats:italic>p<\/jats:italic> = 0.361) were not significantly different between the two\u00a0groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared with the VBA procedure, aBVA is easier for patients with right upper peripheral lung cancer who undergo uni-VATS lobectomy.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fonc.2022.828432","type":"journal-article","created":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T06:54:48Z","timestamp":1643871288000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["aBVA Procedure by Uniportal Video-Assisted Thoracoscopic Surgery for Right Upper Peripheral Lung Cancer: A Randomized Trial"],"prefix":"10.3389","volume":"12","author":[{"given":"Kaiying","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianglun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Langbo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongben","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojun","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,2,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac\/21590","article-title":"Cancer Statistics, 2020","volume":"70","author":"Siegel","year":"2020","journal-title":"CA A Cancer J Clin"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.03.030","article-title":"Lobectomy by Video-Assisted Thoracic Surgery (VATS) Versus Thoracotomy for Lung Cancer","volume":"138","author":"Flores","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-20-2759","article-title":"Uniport vs. Multiport Video-Assisted Thoracoscopic Surgery for Anatomical Lung Resection-Which Is Less Invasive","volume":"13","author":"Matsuura","year":"2001","journal-title":"J Thorac Dis"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13291","article-title":"Does the Length of Uniportal Video-Assisted Thoracoscopic Lobectomy Affect Postoperative Pain? Results of a Randomized Controlled Trial","volume":"11","author":"Menna","year":"2020","journal-title":"Thorac Cancer"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.07.40","article-title":"Predictors of Conversion to Thoracotomy During Video-Assisted Thoracoscopic Surgery Lobectomy in Lung Cancer: Additional Predictive Value of FDG-PET\/CT in a Tuberculosis Endemic Region","volume":"9","author":"Lim","year":"2017","journal-title":"J Thorac Dis"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.04.032","article-title":"Analysis of Unexpected Conversion to Thoracotomy During Thoracoscopic Lobectomy in Lung Cancer","volume":"100","author":"Byun","year":"2015","journal-title":"Ann Thorac Surg"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.05.028","article-title":"Predictors of Conversion to Thoracotomy for Video-Assisted Thoracoscopic Lobectomy: A Retrospective Analysis and the Influence of Computed Tomography\u2013Based Calcification Assessment","volume":"145","author":"Samson","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"key":"B8","unstructured":"EttingerDS\n            WoodDE\n            AisnerD\n            AkerleyW\n            BaumanJR\n            BharatA\n          NCCN Clinical Practice Guidelines in Oncology: Non-Small Cell Lung Cancer. Version 5. 20212021"},{"key":"B9","doi-asserted-by":"publisher","first-page":"85","DOI":"10.21037\/acs.2016.03.07","article-title":"Uniportal Thoracoscopic Surgery: From Medical Thoracoscopy to non-Intubated Uniportal Video-Assisted Major Pulmonary Resections","volume":"5","author":"Gonzalez-Rivas","year":"2016","journal-title":"Ann Cardiothorac Surg"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthoracsur.2012.10.070","article-title":"Uniportal Video-Assisted Thoracoscopic Lobectomy: Two Years of Experience","volume":"95","author":"Gonzalez-Rivas","year":"2013","journal-title":"Ann Thorac Surg"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1974155443","article-title":"Minimization: A New Method of Assigning Patients to Treatment and Control Groups","volume":"15","author":"Taves","year":"1974","journal-title":"Clin Pharmacol Ther"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.317.7155.362","article-title":"Minimisation: The Platinum Standard for Trials? Randomisation Doesn\u2019t Guarantee Similarity of Groups; Minimistaion Does","volume":"317","author":"Treasure","year":"1998","journal-title":"BMJ"},{"key":"B13","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.jtho.2015.09.009","article-title":"The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer","volume":"11","author":"Goldstraw","year":"2016","journal-title":"J Thorac Oncol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3978\/j.issn.2071-1439.2013.07.30","article-title":"Uniportal Video-Assisted Thoracoscopic Lobectomy","volume":"5","author":"Gonzalez-Rivas","year":"2013","journal-title":"J Thorac Dis"},{"key":"B15","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1093\/icvts\/ivv048","article-title":"Thoracoscopic Tunnel Technique for Anatomical Lung Resections: A \u2018Fissure First, Hilum Last\u2019 Approach With Staplers in the Fissureless Patient","volume":"21","author":"Decaluwe","year":"2015","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.21037\/vats.2018.10.03","article-title":"Modified Tube Fixation Technique for Uniportal Video-Assisted Thoracic Surgery","volume":"3","author":"Du","year":"2018","journal-title":"VATS"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-016-1318-4","article-title":"Perioperative Circulating Tumor Cells in Surgical Patients With non-Small Cell Lung Cancer: Does Surgical Manipulation Dislodge Cancer Cells Thus Allowing Them to Pass Into the Peripheral Blood","volume":"46","author":"Sawabata","year":"2016","journal-title":"Surg Today"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.12925","article-title":"Circulating Tumor Cells in the Pulmonary Vein Increase Significantly After Lobectomy: A Prospective Observational Study","volume":"10","author":"Duan","year":"2019","journal-title":"Thorac Cancer"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-20-1636","article-title":"Circulating Tumor Cells Detected Only After Surgery for Non-Small Cell Lung Cancer: Is it a Predictor of Recurrence","volume":"12","author":"Sawabata","year":"2020","journal-title":"J Thorac Dis"},{"key":"B20","doi-asserted-by":"publisher","first-page":"298","DOI":"10.21037\/jtd.2017.12.56","article-title":"Positive Correlation Between Postoperative Tumor Recurrence and Changes in Circulating Tumor Cell Counts in Pulmonary Venous Blood (pvCTC) During Surgical Manipulation in non-Small Cell Lung Cancer","volume":"10","author":"Hashimoto","year":"2018","journal-title":"J Thorac Dis"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2021.694005","article-title":"Effects of Vessel Interruption Sequence During Lobectomy for Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis","volume":"8","author":"Long","year":"2021","journal-title":"Front Surg"},{"key":"B22","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1186\/s40880-017-0220-9","article-title":"Different Dissecting Orders of the Pulmonary Bronchus and Vessels During Right Upper Lobectomy Are Associated With Surgical Feasibility and Postoperative Recovery for Lung Cancer Patients","volume":"36","author":"Zhai","year":"2017","journal-title":"Chin J Cancer"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.2478\/v10039-012-0061-3","article-title":"The Impact of the Sequence of Pulmonary Vessel Ligation During Anatomic Resection for Lung Cancer on Long-Term Survival \u2013 A Prospective Randomized Trial","volume":"58","author":"Kozak","year":"2013","journal-title":"Adv Med Sci"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5223(03)00022-9","article-title":"The Sequence of Vessel Interruption During Lobectomy for non\u2013Small Cell Lung Cancer: Is it Indeed Important","volume":"125","author":"Refaely","year":"2003","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.828432\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T06:54:53Z","timestamp":1643871293000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.828432\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,3]]},"references-count":24,"alternative-id":["10.3389\/fonc.2022.828432"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2022.828432","relation":{},"ISSN":["2234-943X"],"issn-type":[{"type":"electronic","value":"2234-943X"}],"subject":[],"published":{"date-parts":[[2022,2,3]]},"article-number":"828432"}}