{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:44:52Z","timestamp":1770741892973,"version":"3.49.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Mucocele-like tumor of the breast is histologically characterized as mucin-containing cysts with mucin leaking to the stroma. It could be associated with atypical ductal hyperplasia (ADH), ductal carcinoma <jats:italic>in situ<\/jats:italic> (DCIS), and invasive ductal carcinoma (IDC). We report a case of mucocele-like tumor of the breast associated with DCIS confirmed by paraffin section. We review the literature and discuss the imaging features, pathology, and clinical management of the lesion. These lesions demonstrate characteristic imaging features, and we especially highlight the MR characteristics, as they have not been well documented. Performing a diagnostic fine-needle aspiration cytology (FNAC) of mucocele-like tumor carries a risk of tumor underestimation; therefore, excision for all mucocele-like tumors is suggested to be the best approach. However, some recent reports recommend close follow-up for patients with low-risk factors who have mucocele-like tumor without atypia on FNAC.<\/jats:p>","DOI":"10.3389\/fonc.2022.855028","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T16:53:56Z","timestamp":1648486436000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Mucocele-Like Tumor of the Breast Associated With Ductal Carcinoma In Situ"],"prefix":"10.3389","volume":"12","author":[{"given":"Ying","family":"Jiang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Chai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aamer Rasheed","family":"Chughtai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weifang","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"B1","first-page":"88","volume-title":"WHO Classification of Tumors of the Breast","author":"Sunil","year":"2012"},{"key":"B2","doi-asserted-by":"publisher","first-page":"954","DOI":"10.19401\/j.cnki.1007-3639.2021.10.013","article-title":"China Anti-Cancer Association Breast Cancer Diagnosis and Treatment Guideline and Criterion","volume":"31","year":"2021","journal-title":"China Oncol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198607000-00003","article-title":"Mucocele-Like Tumors of the Breast","volume":"10","author":"Rosen","year":"1986","journal-title":"Am J Surg Pathol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9776(96)90057-0","article-title":"Mucocele-Like Tumor of the Breast Associated With Atypical Ductal Hyperplasia or Mucinous Carcinoma. 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Mucocele-Like Tumors of the Breast: Mammographic and Sonographic Appearances","volume":"180","author":"Glazebrook","year":"2003","journal-title":"Am J Roentgenol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.04.0925","article-title":"Benign and Malignant Mucocele-Like Tumors of the Breast: Mammographic and Sonographic Appearances","volume":"185","author":"Kim","year":"2005","journal-title":"Ajr Am J Roentgenol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/j.1075-122X.2005.21437.x","article-title":"Mucocele-Like Lesions of the Breast: A Benign Cause for Indeterminate or Suspicious Mammographic Microcalcifications","volume":"11","author":"Farshid","year":"2015","journal-title":"Breast J"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.5028","article-title":"Mucocele-Like Tumors of the Breast as Cystic Lesions: Sonographic-Pathologic Correlation","volume":"196","author":"Sun","year":"2011","journal-title":"Ajr Am J Roentgenol"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2001.tb143215.x","article-title":"Fibroadenoma of the Breast","volume":"174","author":"Houssami","year":"2001","journal-title":"Med J Aust"},{"key":"B15","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1148\/radiology.220.1.r01jl3113","article-title":"MR Imaging of the Breast for the Detection, Diagnosis, and Staging of Breast Cancer","volume":"220","author":"Orel","year":"2001","journal-title":"Radiology"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1111\/his.12081","article-title":"Outcome of Pure Mucocele-Like Lesions Diagnosed on Breast Core Biopsy","volume":"62","author":"Rakha","year":"2013","journal-title":"Histopathology"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2004.01920.x","article-title":"Surgical Excision is Warranted Following a Core Biopsy Diagnosis of Mucocoele-Like Lesion of the Breast","volume":"45","author":"Carder","year":"2010","journal-title":"Histopathology"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1111\/tbj.12929","article-title":"Mucocele-Like Lesions Diagnosed on Breast Core Biopsy: Low Risk of Upgrade and Subsequent Carcinoma","volume":"24","author":"Zhang","year":"2017","journal-title":"Breast J"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.855028\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T16:54:08Z","timestamp":1648486448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.855028\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":18,"alternative-id":["10.3389\/fonc.2022.855028"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2022.855028","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]},"article-number":"855028"}}