{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:10:58Z","timestamp":1753891858441,"version":"3.41.2"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Till now, the effect of different embolic materials (particulate vs coil) on pre-embolization of carotid body tumors remains poorly understood. The aim of this study was to explore the comparative results between particulate and coil embolization for carotid body tumors. Thirty-seven patients with carotid body tumors who underwent embolization before surgical resection were reviewed and analyzed in this retrospective study between 2008 and 2020. Twenty-one patients were included in the particulate group, while 16 patients were included in the coil group. All procedure-related details, complications and 5-year follow-up data were collected in the study. The preoperative embolization time was obviously longer in the particulate group than in the coil group (42.6 \u00b1 12.3\u00a0min vs. 33.7 \u00b1 10.1\u00a0min, <jats:italic>P<\/jats:italic> =.02), and the fluo time of the procedure (864.5 \u00b1 240.9 s vs. 729.6 \u00b1 251.5 s) and cumulative air kerma (634.6 \u00b1 188.4 mGy vs. 486.7 \u00b1 164.7 mGy) value were higher in the particulate group (<jats:italic>P<\/jats:italic> =.01). The incidences of total adverse events in both groups were not significantly different (28.6% vs. 25.0%, <jats:italic>P<\/jats:italic> &amp;gt;.05); however, two cases of ectopic embolization only occurred in the particulate group. Interestingly, medical expenditure was higher in the particulate group than in the coil group (<jats:italic>P<\/jats:italic> =.02). For the 3-year follow-up evaluation, recurrence and all-cause mortality were similar in both groups (<jats:italic>P<\/jats:italic> &amp;gt;.05). Preoperative embolization with coils could be relatively safe, have a lower radiation dosage and be cost-effective for the treatment of carotid body tumors.<\/jats:p>","DOI":"10.3389\/fonc.2022.860788","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T07:22:21Z","timestamp":1653463341000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["The Comparative Outcomes of Particulate Versus Coil Preoperative Embolization for Carotid Body Tumors"],"prefix":"10.3389","volume":"12","author":[{"given":"Xun","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangjing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianlin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yamin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,5,25]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-020518-114427","article-title":"Physiology of the Carotid Body: From Molecules to Disease","volume":"82","author":"Ortega-Saenz","year":"2019","journal-title":"Annu Rev Physiol"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.10.038","article-title":"A Systematic Review and Meta-Analysis of the Presentation and Surgical Management of Patients With Carotid Body Tumours","volume":"57","author":"Robertson","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/j.ejvs.2018.12.005","article-title":"Carotid Body Tumours: Benign But Challenging","volume":"57","author":"Kakisis","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.106709","article-title":"Surgical Management of Carotid Body Tumors","volume":"123","author":"Wang","year":"2000","journal-title":"Otolaryngol Head Neck Surg"},{"key":"B5","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1227\/NEU.0b013e3181eda61d","article-title":"Preoperative Angiography and Transarterial Embolization in the Management of Carotid Body Tumor: A Single-Center, 10-Year Experience","volume":"67","author":"Li","year":"2010","journal-title":"Neurosurgery"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s002680010272","article-title":"Role of Malignancy and Preoperative Embolization in the Management of Carotid Body Tumors","volume":"24","author":"Liapis","year":"2000","journal-title":"World J Surg"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25387","article-title":"Surgical Resection of Carotid Body Tumors With Versus Without Preoperative Embolization: Retrospective Case-Control Study","volume":"40","author":"Liu","year":"2018","journal-title":"Head Neck"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvscit.2019.07.012","article-title":"Carotid Body Tumor Resection Utilizing a Covered Stent Graft to Enable Resection of the Tumor En Bloc With the Internal Carotid Artery","volume":"5","author":"Alqaim","year":"2019","journal-title":"J Vasc Surg Cases Innov Tech"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.05.031","article-title":"Successful Devascularization of Carotid Body Tumors by Covered Stent Placement in the External Carotid Artery","volume":"48","author":"Scanlon","year":"2008","journal-title":"J Vasc Surg"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1601","article-title":"Percutaneous Embolization of Carotid Paragangliomas Using Solely Onyx","volume":"30","author":"Wanke","year":"2009","journal-title":"AJNR Am J Neuroradiol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(71)90436-3","article-title":"Carotid Body Tumor (Chemodectoma). 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