{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T22:33:13Z","timestamp":1785364393174,"version":"3.55.0"},"reference-count":10,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82001900"],"award-info":[{"award-number":["82001900"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences","doi-asserted-by":"publisher","award":["2021-I2M-1-051"],"award-info":[{"award-number":["2021-I2M-1-051"]}],"id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Prostate cystadenoma is a rare benign prostatic neoplasm, which grows outside prostate and locates midline between the urinary bladder and rectum. It usually presents as multilocular cysts, thus, named giant multilocular prostate cystadenoma. The definite diagnosis is difficult to be made before surgery, and it depends on histopathology. Here, we report a rarer condition of prostate cystadenoma, which manifests as a giant unilocular cyst with a solid nodule inside. The 55-year-old Chinese male patient presented with dysuria and constipation. MRI revealed a 10.5 \u00d7 8.2\u00a0cm mono-cystic lesion displacing the rectum to the posterior, prostate, and bladder to the anterior, with a 2.8 \u00d7 2.1\u00a0cm solid nodule at the anterior wall. <jats:sup>18<\/jats:sup>F-FDG PET\/CT demonstrated an elevated SUV<jats:sub>max<\/jats:sub> (3.5) of the solid nodule. Laparoscopic pelvic mass resection was performed and prostate cystadenoma was diagnosed. In conclusion, when a mass of single locular cyst sits in the male pelvis, the diagnosis of prostate cystadenoma could not be excluded.<\/jats:p>","DOI":"10.3389\/fonc.2022.911442","type":"journal-article","created":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T07:03:54Z","timestamp":1660287834000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case report: Giant unilocular prostate cystadenoma: A rarer condition with a single cystic mass"],"prefix":"10.3389","volume":"12","author":[{"given":"Wenda","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyuan","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Rong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengdan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyu","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,8,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199102000-00005","article-title":"Giant multilocular prostatic cystadenoma: a distinctive lesion of the retroperitoneum in men. a report of two cases","volume":"15","author":"Maluf","year":"1991","journal-title":"Am J Surg Pathol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s12957-019-1579-7","article-title":"Giant multilocular prostatic cystadenoma","volume":"17","author":"Nakamura","year":"2019","journal-title":"World J Surg Oncol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1177\/10935266211073291","article-title":"Giant multilocular prostatic cystadenoma in a 14-Year-Old Male: A case report of a pediatric pelvic mass","volume":"25","author":"Quiring","year":"2022","journal-title":"Pediatr Dev Pathol"},{"key":"B4","article-title":"Giant multilocular prostatic cystadenoma in a 16-year-old male with difficulty in defecation: case report and literature review","volume":"13","author":"Kong","year":"2020","journal-title":"Int J Clin Exp Pathol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjaa244","article-title":"Prostatic cystadenoma presenting as a large multilocular pelvic male mass","volume":"2020","author":"Saadi","year":"2020","journal-title":"J Surg Case Rep"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2019.09.017","article-title":"Giant multilocular prostatic cystadenoma, a diagnosis to consider in large pelvic male masses","volume":"14","author":"Portugal Teixeira","year":"2019","journal-title":"Radiol Case Rep"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.47391\/JPMA.1169","article-title":"Giant dumbbell-shaped prostatic cystadenoma presenting as pelvic and scrotal mass","volume":"71","author":"Zeng","year":"2021","journal-title":"J Pak Med Assoc"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1148\/rg.334125129","article-title":"Cysts of the lower male genitourinary tract: embryologic and anatomic considerations and differential diagnosis","volume":"33","author":"Shebel","year":"2013","journal-title":"Radiographics"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57090870","article-title":"Rapid recurrence of giant multilocular prostatic cystadenoma after laparoscopic excision for primary case: A case report","volume":"57","author":"Choi","year":"2021","journal-title":"Med (Kaunas)"},{"key":"B10","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/s0090-4295(02)02109-x","article-title":"Giant multilocular cystadenoma of the prostate responsive to GnRH antagonists","volume":"61","author":"Datta","year":"2003","journal-title":"Urology"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.911442\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T07:03:59Z","timestamp":1660287839000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2022.911442\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,12]]},"references-count":10,"alternative-id":["10.3389\/fonc.2022.911442"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2022.911442","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,12]]},"article-number":"911442"}}