{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:10:36Z","timestamp":1753891836368,"version":"3.41.2"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T00:00:00Z","timestamp":1686528000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Mediastinal neurogenic tumors primarily originate from the intercostal and sympathetic nerves, whereas schwannomas originating from the brachial plexus are rare. Surgical intervention for such tumors is complex and associated with the risk of postoperative upper limb dysfunction due to their unique anatomical location. In this report, we present the case of a 21-year-old female diagnosed with a mediastinal schwannoma, who underwent a novel surgical approach combining cervical incision and intercostal uniportal video-assisted thoracoscopic surgery (VATS). Our study reviewed the patient\u2019s clinical presentation, treatment approach, pathology, and prognosis. The findings of this study demonstrate that the cervical approach, combined with intercostal uniportal VATS, is a feasible surgical method for the removal of mediastinal schwannomas originating from the brachial plexus.<\/jats:p>","DOI":"10.3389\/fonc.2023.1168963","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T04:31:03Z","timestamp":1686544263000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case report: Combined cervical incision with an intercostal uniportal video-assisted thoracoscopic surgery approach for mediastinal brachial plexus schwannoma"],"prefix":"10.3389","volume":"13","author":[{"given":"Linlin","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihui","family":"Ge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,6,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.11.028","article-title":"Intrathoracic phrenic nerve neurofibroma","volume":"91","author":"Smahi","year":"2011","journal-title":"Ann Thorac Surg"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2010.05504.x","article-title":"A rare case of schwannoma of the intrathoracic phrenic nerve","volume":"80","author":"D\u2019Souza","year":"2010","journal-title":"ANZ J Surg"},{"key":"B3","doi-asserted-by":"publisher","first-page":"106102","DOI":"10.1016\/j.oraloncology.2022.106102","article-title":"Function-preserving intracapsular enucleation of brachial plexus schwannomas: is it safe and effective","volume":"134","author":"Roh","year":"2022","journal-title":"Oral Oncol"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2019.01207","article-title":"Feasibility of brachial plexus schwannoma enucleation with intraoperative neuromonitoring","volume":"13","author":"Lee","year":"2020","journal-title":"Clin Exp Otorhinolaryngol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012880","article-title":"Brachial plexus schwannoma mimicking cervical lymphadenopathy","volume":"97","author":"Ryu","year":"2018","journal-title":"Med (Baltimore)"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2011.274746","article-title":"Single-port video-assisted thoracoscopic left upper lobectomy","volume":"13","author":"Gonzalez-Rivas","year":"2011","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"B7","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1186\/s12885-017-3069-z","article-title":"The feasibility and advantage of uniportal video\u2013assisted thoracoscopic surgery (VATS) in pulmonary lobectomy","volume":"17","author":"Wang","year":"2017","journal-title":"BMC Cancer"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.1039737","article-title":"Would the width of a metal rib spreader affect postoperative pain in patients who undergo video-assisted mini-thoracotomy (VAMT)","volume":"12","author":"Wang","year":"2022","journal-title":"Front Oncol"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-014-3525-x","article-title":"Is surgery for brachial plexus schwannomas safe and effective","volume":"472","author":"Lee","year":"2014","journal-title":"Clin Orthop Relat Res"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.11.114","article-title":"Comparison of the perioperative outcomes in antero-superior mediastinal tumor resection performed by transcervical resection and video-assisted thoracoscopic surgery","volume":"10","author":"Zhu","year":"2018","journal-title":"J Thorac Dis"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivab206","article-title":"Intraoperative neuromonitoring in thoracoscopic excision of brachial plexus schwannoma","volume":"34","author":"Femia","year":"2022","journal-title":"Interact Cardiovasc Thorac Surg"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2023.1168963\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T04:31:05Z","timestamp":1686544265000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2023.1168963\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,12]]},"references-count":11,"alternative-id":["10.3389\/fonc.2023.1168963"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2023.1168963","relation":{},"ISSN":["2234-943X"],"issn-type":[{"type":"electronic","value":"2234-943X"}],"subject":[],"published":{"date-parts":[[2023,6,12]]},"article-number":"1168963"}}