{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:05:32Z","timestamp":1770743132403,"version":"3.49.0"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T00:00:00Z","timestamp":1690329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Giant paratesticular liposarcoma is a rare presentation of paratesticular tumor. We present a case of the largest paratesticular liposarcoma described to date with a weight of 4,100 g and measuring 460 \u00d7 210 \u00d7 130 mm. It was initially mistaken as an inguinoscrotal hernia until a contrast-enhanced computed tomography (CECT) scan of the abdomen and pelvis revealed a huge left paratesticular tumor extending from the scrotum to the mid-abdomen. The challenge was to achieve a tumor-free margin orchidectomy due to the poor fat plane of the tumor to the external iliac artery, psoas muscle, descending colon, and anterior abdominal wall. The surgery was started with laparoscopic dissection for the intraabdominal part of tumor from the vital structure, then followed by inguinal radical orchidectomy and inguinal mesh repair. Postoperative histopathological report revealed a paratesticular dedifferentiated liposarcoma with rhabdomyosarcomatous differentiation with clear margin. The patient had good recovery post operation.<\/jats:p>","DOI":"10.3389\/fonc.2023.1216776","type":"journal-article","created":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T09:52:13Z","timestamp":1690365133000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Giant paratesticular dedifferentiated liposarcoma with intraabdominal extension: a case report"],"prefix":"10.3389","volume":"13","author":[{"given":"Muhammad Hasif","family":"Azizi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iqbal Hussain","family":"Rizuana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yin Ping","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khairiyah","family":"Sidek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xeng Inn","family":"Fam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,7,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"E316","DOI":"10.5489\/cuaj.3346","article-title":"Multidisciplinary approach to giant paratesticular liposarcoma","volume":"10","author":"Sope\u00f1a-Sutil","year":"2016","journal-title":"Can Urological Assoc J"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.28856","article-title":"Giant paratesticular liposarcoma mimicking a left-sided groin hernia: A case report","volume":"14","author":"Chan","year":"2022","journal-title":"Cureus"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2018.1577","article-title":"Giant paratesticular liposarcoma: A case report and review of the literature","volume":"8","author":"Li","year":"2018","journal-title":"Mol Clin Oncol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"rjaa342","DOI":"10.1093\/jscr\/rjaa342","article-title":"Dedifferentiated liposarcoma of the scrotum. 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