{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T22:23:59Z","timestamp":1778192639615,"version":"3.51.4"},"reference-count":21,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Myeloid sarcoma (MS) is a rare extramedullary parenchymal tumor composed of immature myeloid cells, occurring mainly in the lymph nodes, skin, soft tissue, testicles, bones, peritoneum, and gastrointestinal tract, and rarely in the pancreas. Herein, we report the case of a 68-year-old female patient who visited our hospital for medical assistance due to acute abdominal pain. Abdominal computed tomography (CT) and magnetic resonance imaging showed a mass approximately 8 cm in diameter in the pancreatic tail, which was suspected to be a malignant tumor. To further assess the presence of distant metastases, the patient underwent fluorine-18-fluorodeoxyglucose positron emission tomography (<jats:sup>18<\/jats:sup>F-FDG PET)\/CT, which revealed an increased <jats:sup>18<\/jats:sup>F-FDG uptake in the corresponding lesions. Subsequently, the patient underwent surgical treatment, and postoperative pathology and immunohistochemistry revealed that the mass was MS. Moreover, we reviewed the clinical features, imaging findings, and histopathology of pathologically confirmed pancreatic MS in the published literature.<\/jats:p>","DOI":"10.3389\/fonc.2023.1259236","type":"journal-article","created":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T11:43:12Z","timestamp":1695814992000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Multimodal imaging study of pancreatic myeloid sarcoma: a case report and literature review"],"prefix":"10.3389","volume":"13","author":[{"given":"Xianwen","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinyan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1159\/000444516","article-title":"Myeloid sarcoma of the hepatobiliary system: A case series and review of the literature","volume":"135","author":"Norsworthy","year":"2016","journal-title":"Acta Haematol"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2012.10.014","article-title":"Is there a \u201cgold\u201d standard treatment for patients with isolated myeloid sarcoma","volume":"67","author":"Antic","year":"2013","journal-title":"BioMed Pharmacother"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404491","article-title":"Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients","volume":"21","author":"Pileri","year":"2007","journal-title":"Leukemia"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000024913","article-title":"Myeloid sarcoma of the pancreas: A case report and literature review","volume":"100","author":"Wu","year":"2021","journal-title":"Med (Baltimore)"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0000000000003736","article-title":"18F-FDG PET\/CT findings of myeloid sarcoma in the pancreas","volume":"47","author":"Filizoglu","year":"2022","journal-title":"Clin Nucl Med"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.8912-17","article-title":"Isolated pancreatic myeloid sarcoma associated with t (8,21)\/RUNX1-RUNX1T1 rearrangement","volume":"57","author":"Tokunaga","year":"2018","journal-title":"Intern Med"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0609.2003.00021.x","article-title":"Granulocytic sarcoma of the pancreas successfully treated with intensive chemotherapy and stem cell transplantation","volume":"70","author":"Breccia","year":"2003","journal-title":"Eur J Haematol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"7439148","DOI":"10.1155\/2021\/7439148","article-title":"A case of untreated myeloid sarcoma of the pancreas head region: diagnostic process of AML subtyping in an autoptic case","volume":"2021","author":"Fukumura","year":"2021","journal-title":"Case Rep Pathol"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.8462","article-title":"Pancreatic myeloid sarcoma","volume":"12","author":"Al-Obaidi","year":"2020","journal-title":"Cureus"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005570","article-title":"Granulocytic sarcoma of the pancreas on 18F-FDG PET\/CT: A case report","volume":"95","author":"Ishii","year":"2016","journal-title":"Med (Baltimore)"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.1999.00205.x","article-title":"Granulocytic sarcoma of the pancreas: a report of two cases and literature review","volume":"21","author":"Ravandi-Kashani","year":"1999","journal-title":"Clin Lab Haematol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/1471-230X-10-80","article-title":"Granulocytic sarcoma of the pancreas: a case report and review of the literatures","volume":"10","author":"Rong","year":"2010","journal-title":"BMC Gastroenterol"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1159\/000074223","article-title":"Granulocytic sarcoma of the pancreas. A report of one case and review of the literature","volume":"110","author":"Servin-Abad","year":"2003","journal-title":"Acta Haematol"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v6.i11.477","article-title":"Isolated myeloid sarcoma in the pancreas and orbit: A case report and review of literature","volume":"6","author":"Zhu","year":"2018","journal-title":"World J Clin Cases"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i4.540","article-title":"Isolated pancreatic granulocytic sarcoma: a case report and review of the literature","volume":"17","author":"Li","year":"2011","journal-title":"World J Gastroenterol"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.12.9057","article-title":"MRI for evaluation of myeloid sarcoma in adults: a single-institution 10-year experience","volume":"199","author":"Shinagare","year":"2012","journal-title":"AJR Am J Roentgenol"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.7869\/tg.247","article-title":"Serous cystadenoma of pancreas: imaging diagnosis","volume":"36","author":"Yadav","year":"2015","journal-title":"Trop Gastroenterol"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2017.10.006","article-title":"Solid pseudopapillary tumor of the pancreas: clinical features and imaging findings","volume":"48","author":"Li","year":"2018","journal-title":"Clin Imaging"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-2-42","article-title":"Myeloid sarcomas: a histologic, immunohistochemical, and cytogenetic study","volume":"2","author":"Alexiev","year":"2007","journal-title":"Diagn Pathol"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2004.01.022","article-title":"Clinico-pathological characteristics of myeloid sarcoma at diagnosis and during follow-up: report of 12 cases from a single institution","volume":"28","author":"Breccia","year":"2004","journal-title":"Leuk Res"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastrohep.2019.04.008","article-title":"First case report of pancreatic myeloid sarcoma diagnosed through EUS-FNA","volume":"42","author":"Nunes","year":"2019","journal-title":"Gastroenterol Hepatol"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2023.1259236\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T11:43:15Z","timestamp":1695814995000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2023.1259236\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":21,"alternative-id":["10.3389\/fonc.2023.1259236"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2023.1259236","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,26]]},"article-number":"1259236"}}