{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:11:24Z","timestamp":1753891884460,"version":"3.41.2"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The anesthetic management of patients with glucagonoma is complicated by a number of factors including glucose fluctuation, characterized necrolytic migratory erythema in oral and pharyngeal, which may lead to an unexpected difficult airway.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>Herein we describe the anesthetic considerations and management of a 47-year-old adult with glucagonoma, who presented for a laparoscopic splenectomy and distal pancreatectomy procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This report details fiberoptic intubation in an adult with glucagonoma and necrolytic migratory erythema. We recommend that this approach be considered in patients with glucagonoma and severe necrolytic migratory erythema undergoing general anesthesia.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fonc.2024.1408506","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T06:24:29Z","timestamp":1734589469000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report: Anesthesia management for surgical treatment of glucagonoma with symptom of characterized necrolytic migratory erythema"],"prefix":"10.3389","volume":"14","author":[{"given":"Di","family":"Xia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Le","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.3109\/07435800.2010.525085","article-title":"Pancreatic neuroendocrine tumors","volume":"36","author":"Batcher","year":"2011","journal-title":"Endocr Res"},{"key":"B2","doi-asserted-by":"publisher","first-page":"9053","DOI":"10.1038\/s41598-022-12882-2","article-title":"Dong S et\u00a0al: Necrolytic migratory erythema is an important visual cutaneous clue of glucagonoma","volume":"12","author":"Li","year":"2022","journal-title":"Sci Rep"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.7703","article-title":"Glucagonoma and the glucagonoma syndrome","volume":"15","author":"Song","year":"2018","journal-title":"Oncol Lett"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-255X(98)80039-5","article-title":"Surgical experience with pancreatic and peripancreatic neuroendocrine tumors: review of 125 patients","volume":"2","author":"Phan","year":"1998","journal-title":"J Gastrointest Surg"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0000000000000891","article-title":"Glucagonoma pancreatic neuroendocrine tumor treated with 177Lu DOTATATE induction and maintenance peptide receptor radionuclide therapy","volume":"40","author":"Makis","year":"2015","journal-title":"Clin Nucl Med"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2005.05.004","article-title":"Rare endocrine tumours of the GI tract","volume":"19","author":"Doherty","year":"2005","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-91-2-213","article-title":"Amino acid deficiency and the skin rash associated with glucagonoma","volume":"91","author":"Norton","year":"1979","journal-title":"Ann Intern Med"},{"key":"B8","article-title":"Necrolytic migratory erythema with carcinoma of the pancreas","volume":"59","author":"Wilkinson","year":"1973","journal-title":"Trans St Johns Hosp Dermatol Soc"},{"key":"B9","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/j.bpg.2012.12.006","article-title":"Biochemical markers for gastroenteropancreatic neuroendocrine tumours (GEP-NETs)","volume":"26","author":"Kanakis","year":"2012","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017037","article-title":"Spleen-preserving distal pancreatectomy and lymphadenectomy for glucagonoma syndrome: A case report","volume":"98","author":"Cao","year":"2019","journal-title":"Med (Baltimore)"},{"key":"B11","doi-asserted-by":"publisher","first-page":"9630716","DOI":"10.1155\/2022\/9630716","article-title":"Sufentanil alleviates sepsis-induced myocardial injury and stress response in rats through the ERK\/GSK-3beta signaling axis","volume":"2022","author":"Zang","year":"2022","journal-title":"Evid Based Complement Alternat Med"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1007\/BF03017409","article-title":"Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists","volume":"49","author":"Kato","year":"2002","journal-title":"Can J Anaesth"},{"key":"B13","article-title":"Glucagonoma: anaesthetic management","volume":"37","author":"Gin","year":"2009","journal-title":"Anaesth Intensive Care"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1210\/endrev\/bnaa031","article-title":"Multiple endocrine neoplasia type 1: latest insights","volume":"42","author":"Brandi","year":"2021","journal-title":"Endocr Rev"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1159\/000511791","article-title":"Multiple Endocrine Neoplasia Type 1 and the Pancreas: Diagnosis and Treatment of Functioning and Non-Functioning Pancreatic and Duodenal Neuroendocrine Neoplasia within the MEN1 Syndrome - 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