{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:10:50Z","timestamp":1753891850955,"version":"3.41.2"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>A 47-year-old woman with a two-month history of right inguinal lymphadenopathy visited Shanghai Pudong New Area People\u2019s Hospital for a biopsy. Histopathological and immunohistochemical analyses revealed a metastasis of high-grade serous carcinoma, likely of gynecological origin. A PET-CT scan identified a tumor in the left adnexa, with no other organ involvement. The patient underwent primary cytoreduction, including laparoscopy, hysterosalpingo-oophorectomy, omentectomy, and resection of the right deep inguinal lymph nodes at the Hospital of Obstetrics and Gynecology. No residual disease was found post-surgery. Pathological examination revealed high-grade serous cancer in the fimbria of the left fallopian tube and left ovary, while the right deep inguinal lymph nodes were negative. The patient received standard chemotherapy (Carboplatin and Taxol) and showed no new lesions after three cycles, as confirmed by imaging.<\/jats:p>","DOI":"10.3389\/fonc.2025.1486688","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T05:23:03Z","timestamp":1738819383000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["High-grade serous cancer of left fallopian tube with right inguinal lymph node enlargement: a case report"],"prefix":"10.3389","volume":"15","author":[{"given":"Aizhi","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiyong","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenfeng","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"B2","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1186\/s12905-022-02104-2","article-title":"Analysis of the disease burden trend of Malignant tumors of the female reproductive system in China from 2006 to 2020","volume":"22","author":"Han","year":"2022","journal-title":"BMC Womens Health"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19891001)64:7<1508::AID-CNCR2820640725>3.0.CO;2-V","article-title":"Metastatic patterns in histologic variants of ovarian cancer","volume":"64","author":"Rose","year":"1989","journal-title":"autopsy study. 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