{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T23:31:36Z","timestamp":1780356696946,"version":"3.54.1"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Hemolymphangioma is a rare benign tumor, with only 12 reported cases in the pancreas as of May 2024. We present an invasive and giant hemolymphangioma of the pancreas in a young man who experienced abdominal pain and left epigastric distension for approximately 10 days. Imaging studies revealed a large cystic tumor located in the body and tail of the pancreas, which was compressing the partial lesser curvature of the stomach and spleen, displaying a \u201cbeaver tail\u201d liver appearance on computed tomography scans. After surgery, he was diagnosed with hemolymphangioma of the pancreas, and there were no signs of recurrence upon follow-up. We conclude that diagnosing hemolymphangioma of the pancreas can be challenging. Whenever possible, radical surgical resection should be performed, and long-term follow-up is essential.<\/jats:p>","DOI":"10.3389\/fonc.2025.1524739","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T07:09:57Z","timestamp":1739430597000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Case report: An invasive and giant hemolymphangioma of the pancreas in a young man"],"prefix":"10.3389","volume":"15","author":[{"given":"Pin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mancai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongyong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000437","article-title":"CT findings and clinical features of pancreatic hemolymphangioma: a case report and review of the literature","volume":"94","author":"Pan","year":"2015","journal-title":"Med (Baltimore)"},{"key":"B2","doi-asserted-by":"publisher","first-page":"399","DOI":"10.6092\/1590-8577\/2649","article-title":"Pancreatic hemolymphangioma","volume":"15","author":"Figueroa","year":"2014","journal-title":"JOP"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012599","article-title":"A giant hemolymphangioma of the pancreas: A case report and literature review","volume":"97","author":"Chen","year":"2018","journal-title":"Med (Baltimore)"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-7-31","article-title":"A giant hemolymphangioma of the pancreas in a 20-year-old girl: a report of one case and review of the literature","volume":"7","author":"Sun","year":"2009","journal-title":"World J Surg Oncol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.2932","article-title":"A case of invasive hemolymphangioma of the pancreas","volume":"14","author":"Toyoki","year":"2008","journal-title":"World J Gastroenterol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2018.08.030","article-title":"A rare case of retroperitoneal hemolymphangioma","volume":"51","author":"Ohsawa","year":"2018","journal-title":"Int J Surg Case Rep"},{"key":"B7","doi-asserted-by":"publisher","first-page":"798","DOI":"10.2174\/1386207322666190103110747","article-title":"An invasive hemolymphangioma of the pancreas in a young woman","volume":"21","author":"Zhang","year":"2018","journal-title":"Comb Chem High Throughput Screen"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i22.3520","article-title":"Hemolymphangioma: a rare differential diagnosis of cystic-solid or cystic tumors of the pancreas","volume":"19","author":"Dong","year":"2013","journal-title":"World J Gastroenterol"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1097\/00006676-200308000-00014","article-title":"Hemolymphangioma of the pancreas: case report and review of the literature","volume":"27","author":"Balderramo","year":"2003","journal-title":"Pancreas"},{"key":"B10","article-title":"Les h\u00e9mo-lymphangiomes du pancr\u00e9as [Hemolymphangioma of the pancreas","volume":"122","author":"Montete","year":"1985","journal-title":"J Chir (Paris)"},{"key":"B11","article-title":"Considerazioni su un caso di emolinfangioma del pancreas [A case of hemolymphangioma of the pancreas","volume":"42","author":"Banchini","year":"1987","journal-title":"Minerva Chir"},{"key":"B12","article-title":"H\u00e9mo-lymphangiome de la t\u00eate du pancr\u00e9as [Hemolymphangioma of the head of the pancreas","volume":"92","author":"Couinaud","year":"1966","journal-title":"Mem Acad Chir (Paris)"},{"key":"B13","article-title":"Une tumeur rare de la t\u00eate du pancr\u00eaas. (Hemolymphangiome de 1,500 kg) [A rare tumor of the head of the pancreas. (Hemolymphangioma weighing 1,500 kg.)","volume":"75","author":"Couinaud","year":"1967","journal-title":"Presse Med (1893)"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.21037\/tcr-21-176","article-title":"Hemolymphangioma of the transverse mesocolon: a case report and literature review","volume":"10","author":"Li","year":"2021","journal-title":"Transl Cancer Res"},{"key":"B15","doi-asserted-by":"publisher","first-page":"798","DOI":"10.2174\/1386207322666190103110747","article-title":"An invasive hemolymphangioma of the pancreas in a young woman","volume":"21","author":"Zhang","year":"2018","journal-title":"Comb Chem High Throughput Screen"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1524739\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T07:10:02Z","timestamp":1739430602000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1524739\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,13]]},"references-count":15,"alternative-id":["10.3389\/fonc.2025.1524739"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2025.1524739","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,13]]},"article-number":"1524739"}}