{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T14:58:36Z","timestamp":1756738716773,"version":"3.44.0"},"reference-count":7,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Implantation metastasis of gastric cancer to the inguinal area is rarely reported, and a clear diagnosis of such metastasis is hard to make, especially when these cancers are invisible on fluorodeoxyglucose (FDG) positron emission tomography\/computed tomography (PET\/CT) imaging. However, certain types of cancers, such as signet-ring cell carcinoma, are particularly sensitive to fibroblast activation protein inhibitor (FAPI) PET\/CT. In this case, a patient with a history of gastric cancer and a gastrectomy 2 years previously suddenly developed serious edema in his right lower limb. With the help of FAPI PET\/CT and other laboratory findings, abdominal implantation of his primary gastric cancer to the inguinal region was confirmed. After prompt treatment, the patient had a favorable prognosis.<\/jats:p>","DOI":"10.3389\/fonc.2025.1549825","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T04:10:48Z","timestamp":1751947848000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Detection of gastric cancer with implantation metastasis to the inguinal region via 18F-FAPI PET\/CT: a case report"],"prefix":"10.3389","volume":"15","author":[{"given":"Haibo","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanhu","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongbao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuantong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.88335","article-title":"Evaluation of FAPI PET imaging in gastric cancer: a systematic review and meta-analysis","volume":"13","author":"Ruan","year":"2023","journal-title":"Theranostics"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.120.258467","article-title":"(68)Ga-DOTA-FAPI-04 PET\/MR in the evaluation of gastric carcinomas: comparison with (18)F-FDG PET\/CT","volume":"63","author":"Qin","year":"2022","journal-title":"J Nucl Med"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.122.264689","article-title":"Fibroblast-Activation protein PET and histopathology in a single-Center database of 324 patients and 21 tumor entities","volume":"64","author":"Hirmas","year":"2023","journal-title":"J Nucl Med"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2021.07.011","article-title":"FAPI PET\/CT research progress in digestive system tumours","volume":"54","author":"Peng","year":"2022","journal-title":"Dig Liver Dis"},{"key":"B5","doi-asserted-by":"publisher","first-page":"40","DOI":"10.2967\/jnumed.123.266329","article-title":"Fibroblast activation protein-targeted PET\/CT with (18)F-fibroblast activation protein inhibitor-74 for evaluation of gastrointestinal cancer: comparison with (18)F-FDG PET\/CT","volume":"65","author":"Xu","year":"2024","journal-title":"J Nucl Med"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.14989\/ActaUrolJap_66_5_157","article-title":"A case of subcutaneous scrotal metastasis from primary gastric cancer","volume":"66","author":"Sekita","year":"2020","journal-title":"Hinyokika Kiyo"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1105080","article-title":"Case report: A case of delayed cutaneous metastases from signet-ring cell mixed-type gastric cancer","volume":"13","author":"Yao","year":"2023","journal-title":"Front Oncol"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1549825\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T04:10:49Z","timestamp":1751947849000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1549825\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,8]]},"references-count":7,"alternative-id":["10.3389\/fonc.2025.1549825"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2025.1549825","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,8]]},"article-number":"1549825"}}