{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:48:12Z","timestamp":1777614492175,"version":"3.51.4"},"reference-count":10,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:p>Doege\u2013Potter syndrome or non-islet cell tumor hypoglycemia (NICTH) is a rare entity usually due to a solitary fibrous tumor of the pleura (pSFT). The diagnosis of NICTH is challenging because of its non-specific clinical presentation and the rarity of pSFT. We present a case report of a 44-year-old woman diagnosed with NICTH to demonstrate the difficulty of establishing this diagnosis and the importance of preoperative preparation based on the characteristics of the lesion. We performed an embolization followed by an en bloc resection with diaphragmatic patch and lung wedge resection, and we subsequently reconstructed the diaphragm with Prolene mesh through a left hemiclamshell incision. The postoperative course was favorable, particularly the resolution of hypoglycemia, which was concordant with the diagnosis. Pathological examination revealed a pSFT with clean margins and no features of malignancy detected by immunohistochemistry. This case report highlights the fact that diagnosing Doege\u2013Potter syndrome is not always easy and often takes time after the patient\u2019s initial presentation, the importance of preoperative planning, and the benefits of preoperative embolization of the arterial feeder.<\/jats:p>","DOI":"10.3389\/fonc.2025.1550343","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T05:37:04Z","timestamp":1749015424000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Doege\u2013Potter syndrome: a giant solitary fibrous pleural tumor causing severe hypoglycemia"],"prefix":"10.3389","volume":"15","author":[{"given":"Christelle","family":"De Vico","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Tappero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enzo","family":"Fontana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon Andri","family":"Lutz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beno\u00eet","family":"Rouiller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/s13019-022-01881-z","article-title":"Resection of giant Malignant solitary fibrous pleural tumor after interventional embolization: a case report and literature review","volume":"17","author":"Yao","year":"2022","journal-title":"J Cardiothorac Surg"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15164166","article-title":"Surgery for solitary fibrous tumors of the pleura: A review of the available evidence","volume":"15","author":"Bertoglio","year":"2023","journal-title":"Cancers (Basel)"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-7-11","article-title":"Doege-Potter syndrome presenting with hypoinsulinemic hypoglycemia in a patient with a Malignant extrapleural solitary fibrous tumor: a case report","volume":"7","author":"Schutt","year":"2013","journal-title":"J Med Case Rep"},{"key":"B4","volume-title":"Shield\u2019s General Thoracic Surgery","author":"LoCicero","year":"2019"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.10.044","article-title":"Solitary fibrous tumor of the pleura with abdominal aortic blood supply","volume":"103","author":"Addagatla","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"B6","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1186\/s13019-024-02872-y","article-title":"Resection of pleural solitary fibrous tumors with distinct feeding vessels arising from the descending aorta: a case report","volume":"19","author":"Li","year":"2024","journal-title":"J Cardiothorac Surg"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1515\/med-2016-0042","article-title":"Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature","volume":"11","author":"Perrotta","year":"2016","journal-title":"Open Med (Wars)"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e7417","DOI":"10.1097\/MD.0000000000007417","article-title":"Doege-Potter syndrome: A review of the literature including a new case report","volume":"96","author":"Han","year":"2017","journal-title":"Med (Baltimore)"},{"key":"B9","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/s13019-017-0630-4","article-title":"Doege-potter syndrome: a report of a histologically benign but clinically Malignant case","volume":"12","author":"Kim","year":"2017","journal-title":"J Cardiothorac Surg"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2015.0023","article-title":"Doege-potter syndrome","volume":"97","author":"Ahluwalia","year":"2015","journal-title":"Ann R CollSurg Engl"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1550343\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T05:37:05Z","timestamp":1749015425000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1550343\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,4]]},"references-count":10,"alternative-id":["10.3389\/fonc.2025.1550343"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2025.1550343","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,4]]},"article-number":"1550343"}}