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This case highlights the importance of clinicians maintaining a heightened awareness and clinical vigilance regarding multiple primary cancers, ensuring patients receive comprehensive diagnosis and treatment for improved prognosis and desired survival outcomes.<\/jats:p>","DOI":"10.3389\/fonc.2025.1558347","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:40:36Z","timestamp":1747201236000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Rare comorbidity of colon cancer, hepatic malignant mesothelioma, and abdominal Ewing\u2019s sarcoma: a case 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