{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:03:19Z","timestamp":1756512199671,"version":"3.44.0"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The study aimed to evaluate the current status of swallowing function and quality of life in patients undergoing posterior skull base surgery, identify risk factors for dysphagia, and provide evidence for early interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Patients undergoing posterior skull base surgery were prospectively enrolled, from June 2023 to June 2024. Data collection included demographics, disease-related details, swallowing function assessment, and scores of Swallowing-Quality of Life (SWAL-QOL). The logistic regression was used to identify risk factors influencing dysphagia, while the SWAL-QOL questionnaire was used to investigate the quality of life in patients undergoing posterior skull base surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 143 patients, approximately 50% developed postoperative dysphagia. Logistic regression analysis identified a history of choking, surgical duration, and the total score of nutritional risk as independent predictors of dysphagia. The area under the Receiver Operating Characteristic Curve was 0.797 (95%CI: 0.722\u20130.871). The SWAL-QOL questionnaire revealed significantly lower scores across all dimensions in patients with dysphagia (<jats:italic>P<\/jats:italic> &amp;lt; 0.05), particularly in swallowing function, eating duration, and food selection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Postoperative dysphagia is prevalent after posterior skull base surgery and significantly impairs quality of life. Routine screening and proactive management of swallowing function are essential for improving clinical outcomes and enhancing swallowing-related quality of life.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fonc.2025.1582176","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T04:11:40Z","timestamp":1756440700000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk factors and quality of life in adults with dysphagia after posterior skull base surgery: a cross-sectional study"],"prefix":"10.3389","volume":"15","author":[{"given":"Qiao","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shang-Jin","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Yao","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Jie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-011-1433-x","article-title":"Incidence of mutism, dysarthria and dysphagia associated with childhood posterior fossa tumor","volume":"27","author":"Mei","year":"2011","journal-title":"Child Nerv Syst"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003107","article-title":"Predictors of postoperative complications in vestibular schwannoma surgery-A population-based study","volume":"42","author":"Alkins","year":"2021","journal-title":"Otol Neurotol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2013.01.035","article-title":"Dysphagia following posterior fossa surgery in adults","volume":"82","author":"Wadhwa","year":"2014","journal-title":"World Neurosurg"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2021.05.013","article-title":"Dysphagia and swallowing disorders","volume":"105","author":"McCarty","year":"2021","journal-title":"Med Clin N Am"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2023.09.069","article-title":"Intraoperative neurophysiologic monitoring in predicting dysphagia after brainstem and fourth ventricle surgery","volume":"180","author":"Lapteva","year":"2023","journal-title":"World Neurosurg"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S107750","article-title":"European Society for Swallowing Disorders European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome","volume":"11","author":"Baijens","year":"2016","journal-title":"Clin Interv Aging"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.12968\/bjcn.2015.20.Sup6a.S28","article-title":"Dysphagia: its nature, assessment and management","volume":"20","author":"Lancaster","year":"2015","journal-title":"Br J Community Nursing"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13695","article-title":"Effect of a gum-based thickener on the safety of swallowing in patients with poststroke oropharyngeal dysphagia","volume":"31","author":"Bolivar-Prados","year":"2019","journal-title":"Neurogastroent Motil"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1177\/15459683211023187","article-title":"Effect of transcutaneous electrical stimulation in chronic poststroke patients with oropharyngeal dysphagia: 1-year results of a randomized controlled trial","volume":"35","author":"Arreola","year":"2021","journal-title":"Neurorehab Neural Re"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1177\/0194599811429259","article-title":"Prevalence, characteristics, and management of swallowing disorders following cerebellopontine angle surgery","volume":"146","author":"Starmer","year":"2012","journal-title":"Otolaryng Head Neck"},{"key":"B11","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1186\/s12885-024-12656-1","article-title":"Prevalence of dysphagia following posterior fossa tumor resection: a systematic review and meta\u2212analysis","volume":"24","author":"Duan","year":"2024","journal-title":"BMC Cancer"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-006-0065-z","article-title":"Postoperative swallowing function after posterior fossa tumor resection in pediatric patients","volume":"22","author":"Newman","year":"2006","journal-title":"Child Nerv Syst"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-008-9524-6","article-title":"Pre and post-surgical dysphagia outcome associated with posterior fossa tumor in children","volume":"87","author":"Morgan","year":"2008","journal-title":"J Neuro-Oncol"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1177\/000348940811701210","article-title":"Validity and reliability of the eating assessment tool (EAT-10)","volume":"117","author":"Belafsky","year":"2008","journal-title":"Ann Oto Rhinol Laryn"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1044\/2025_JSLHR-24-00671","article-title":"Reliability and validity of the chinese mandarin version of the 10-item eating assessment tool in community-dwelling older adults","volume":"68","author":"Zeng","year":"2025","journal-title":"J Speech Lang Hear Res."},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-022-10486-6","article-title":"Diagnostic accuracy of the eating assessment tool-10 (EAT-10) in screening dysphagia: A systematic review and meta-analysis","volume":"38","author":"Zhang","year":"2023","journal-title":"Dysphagia"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1007\/s004550010013","article-title":"The SWAL-QOL outcomes tool for oropharyngeal dysphagia in adults: II. Item reduction and preliminary scaling","volume":"15","author":"McHorney","year":"2000","journal-title":"Dysphagia"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-4356(96)00236-3","article-title":"A simulation study of the number of events per variable in logistic regression analysis","volume":"49","author":"Peduzzi","year":"1996","journal-title":"J Clin Epidemiol"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16137","article-title":"Swallowing disorders in the older population","volume":"67","author":"Christmas","year":"2019","journal-title":"J Am Geriatr Soc"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-002-0054-7","article-title":"Aspiration risk after acute stroke: Comparison of clinical examination and fiberoptic endoscopic evaluation of swallowing","volume":"17","author":"Leder","year":"2002","journal-title":"Dysphagia"},{"key":"B21","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s42466-019-0021-5","article-title":"Safety and clinical impact of FEES \u2013 results of the FEES-registry","volume":"1","author":"Dziewas","year":"2019","journal-title":"Neurol Res Practice"},{"key":"B22","doi-asserted-by":"publisher","first-page":"2561","DOI":"10.3390\/cancers12092561","article-title":"Pre- and post-surgical dysphagia in adults with tumors of the posterior fossa: A prospective blinded study","volume":"12","author":"Lapa","year":"2020","journal-title":"Cancers"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1111\/1747-0080.12385","article-title":"High nutrition risk is associated with higher risk of dysphagia in advanced age adults newly admitted to hospital","volume":"75","author":"Popman","year":"2018","journal-title":"Nutr Diet"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000190056.76543.eb","article-title":"Dysphagia after stroke - Incidence, diagnosis, and pulmonary complications","volume":"36","author":"Martino","year":"2005","journal-title":"Stroke"},{"key":"B25","doi-asserted-by":"publisher","first-page":"140","DOI":"10.3390\/geriatrics9060140","article-title":"The functional capacity of the upper airway in older adults with chronic stroke","volume":"9","author":"Prados-Roman","year":"2024","journal-title":"Geriatrics (Basel)"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1097\/corr.0000000000001236","article-title":"Minimum clinically important differences of the hospital for special surgery dysphagia and dysphonia inventory and other dysphagia measurements in patients undergoing ACDF","volume":"478","author":"Okano","year":"2020","journal-title":"Clin Orthop Relat Res"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.605687","article-title":"Risk score for predicting dysphagia in patients after neurosurgery: A prospective observational trial","volume":"12","author":"Zeng","year":"2021","journal-title":"Front Neurol"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1582176\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T04:11:40Z","timestamp":1756440700000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1582176\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,29]]},"references-count":27,"alternative-id":["10.3389\/fonc.2025.1582176"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2025.1582176","relation":{},"ISSN":["2234-943X"],"issn-type":[{"value":"2234-943X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,29]]},"article-number":"1582176"}}