{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T18:49:38Z","timestamp":1755802178504,"version":"3.44.0"},"reference-count":9,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Oncol."],"abstract":"Introduction<\/jats:title>Facial scars are generally disfiguring and can cause both physiological and psychological trauma. Currently, there is a lack of effective treatment options for facial scars. In recent years, local superficial radiation therapy has emerged as a clinically proven treatment to effectively prevent scar recurrence after surgery.<\/jats:p><\/jats:sec>Case presentation<\/jats:title>Our patient was a 41-year-old male with a disfiguring facial scar caused by extensive burns. The patient underwent surgery for his facial scar; however, the scar recurred after surgery. Then, the patient underwent superficial radiotherapy, after which the patient\u2019s facial scar flattened gradually, and his face was restored to normal. No significant adverse reactions were observed after 1 year of follow-up.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The results indicate that superficial radiotherapy may promote the atrophy of hypertrophic scar tissue and can restore the normal appearance of the skin by reshaping the wound repair process.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fonc.2025.1586196","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T05:28:14Z","timestamp":1755754094000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful treatment of disfiguring facial scar using surgery combined with superficial radiotherapy: a case report with literature review"],"prefix":"10.3389","volume":"15","author":[{"given":"Yong-xia","family":"Zong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinghua","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ze","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"101815","DOI":"10.1016\/j.redox.2020.101815","article-title":"Altered glucose metabolism and cell function in keloid fibroblasts under hypoxia","volume":"38","author":"Wang","year":"2021","journal-title":"Redox Biol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e13926","DOI":"10.1002\/acm2.13926","article-title":"Implementation of superficial radiation therapy (SRT) using SRT-100 Vision\u2122 for non-melanoma skin cancer in a Radiation Oncology clinic","volume":"24","author":"Lee","year":"2023","journal-title":"J Appl Clin Med Phys"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v16i2.5182","article-title":"Commissioning a 50\u2013100 kV X-ray unit for skin cancer treatment","volume":"16","author":"Sheu","year":"2015","journal-title":"J Appl Clin Med Phys"},{"key":"B4","doi-asserted-by":"publisher","first-page":"e4796","DOI":"10.1097\/GOX.0000000000004796","article-title":"Multimodal management of facial keloid with tissue expansion, excision, and injection of 5-FU and triamcinolone","volume":"11","author":"Marquez","year":"2023","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"B5","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.bjps.2007.05.007","article-title":"Levels of evidence for the treatment of keloid disease","volume":"61","author":"Durani","year":"2008","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"B6","article-title":"Surgical excision followed by low dose rate radiotherapy in the management of resistant keloids","volume":"2","author":"Mohammadi","year":"2013","journal-title":"World J Plast Surg"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.1043840","article-title":"Current advances in the selection of adjuvant radiotherapy regimens for keloid","volume":"9","author":"Wang","year":"2022","journal-title":"Front Med (Lausanne)"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(88)90119-8","article-title":"Role of ionizing irradiation for 393 keloids","volume":"15","author":"Borok","year":"1988","journal-title":"Int J Radiat Oncol"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000056869.31142.DE","article-title":"Treatment of keloids by surgical excision and immediate postoperative single-fraction radiotherapy","volume":"111","author":"Ragoowansi","year":"2003","journal-title":"Plast Reconstr Surg"}],"container-title":["Frontiers in Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1586196\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T05:28:15Z","timestamp":1755754095000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2025.1586196\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,21]]},"references-count":9,"alternative-id":["10.3389\/fonc.2025.1586196"],"URL":"https:\/\/doi.org\/10.3389\/fonc.2025.1586196","relation":{},"ISSN":["2234-943X"],"issn-type":[{"type":"electronic","value":"2234-943X"}],"subject":[],"published":{"date-parts":[[2025,8,21]]},"article-number":"1586196"}}